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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Wallerian Degeneration

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Disease relevance of Wallerian Degeneration


High impact information on Wallerian Degeneration


Chemical compound and disease context of Wallerian Degeneration


Biological context of Wallerian Degeneration


Anatomical context of Wallerian Degeneration


Gene context of Wallerian Degeneration


Analytical, diagnostic and therapeutic context of Wallerian Degeneration


  1. Axonal injury in the cerebral normal-appearing white matter of patients with multiple sclerosis is related to concurrent demyelination in lesions but not to concurrent demyelination in normal-appearing white matter. Narayanan, S., Francis, S.J., Sled, J.G., Santos, A.C., Antel, S., Levesque, I., Brass, S., Lapierre, Y., Sappey-Marinier, D., Pike, G.B., Arnold, D.L. Neuroimage (2006) [Pubmed]
  2. Supplemental myo-inositol prevents L-fucose-induced diabetic neuropathy. Sima, A.A., Dunlap, J.A., Davidson, E.P., Wiese, T.J., Lightle, R.L., Greene, D.A., Yorek, M.A. Diabetes (1997) [Pubmed]
  3. Extent of pontine pyramidal tract Wallerian degeneration and outcome after supratentorial hemorrhagic stroke. Fukui, K., Iguchi, I., Kito, A., Watanabe, Y., Sugita, K. Stroke (1994) [Pubmed]
  4. Hyperexcitability of axotomized and neighboring unaxotomized sensory neurons is reduced days after perineural clonidine at the site of injury. Liu, B., Eisenach, J.C. J. Neurophysiol. (2005) [Pubmed]
  5. Could Wallerian degeneration contribute to "leuko-araiosis" in subjects free of any vascular disorder? Leys, D., Pruvo, J.P., Parent, M., Vermersch, P., Soetaert, G., Steinling, M., Delacourte, A., Défossez, A., Rapoport, A., Clarisse, J. J. Neurol. Neurosurg. Psychiatr. (1991) [Pubmed]
  6. A local mechanism mediates NAD-dependent protection of axon degeneration. Wang, J., Zhai, Q., Chen, Y., Lin, E., Gu, W., McBurney, M.W., He, Z. J. Cell Biol. (2005) [Pubmed]
  7. Axolemma is a mitogen for human Schwann cells. Sobue, G., Brown, M.J., Kim, S.U., Pleasure, D. Ann. Neurol. (1984) [Pubmed]
  8. Wallerian degeneration involves Rho/Rho-kinase signaling. Yamagishi, S., Fujitani, M., Hata, K., Kitajo, K., Mimura, F., Abe, H., Yamashita, T. J. Biol. Chem. (2005) [Pubmed]
  9. Physiological consequences of antiserum-mediated experimental demyelination in CNS. Kaji, R., Suzumura, A., Sumner, A.J. Brain (1988) [Pubmed]
  10. Induction of rat E and chicken A-I apolipoproteins and mRNAs during optic nerve degeneration. Dawson, P.A., Schechter, N., Williams, D.L. J. Biol. Chem. (1986) [Pubmed]
  11. Changes in composition of endoneurial and perineurial fatty acids during glycerol-induced Wallerian degeneration and regeneration in the sciatic nerve of the adult rat. Fressinaud, C., Vallat, J.M., Durand, J., Archambeaud-Mouveroux, F., Rigaud, M. J. Neurochem. (1987) [Pubmed]
  12. Effect of Wallerian degeneration on histamine concentration of the peripheral nerve. MacDonald, S.M., Mezei, M., Mezei, C. J. Neurochem. (1981) [Pubmed]
  13. The effect of diabetes, insulin and Wallerian degeneration on leucine metabolism of isolated rat sciatic nerves. Buse, M.G., Herlong, H.F., Weigand, D.A., Spicer, S.S. J. Neurochem. (1976) [Pubmed]
  14. Early stimulation of phosphatidylcholine biosynthesis during Wallerian degeneration of rat sciatic nerve. Natarajan, V., Yao, J.K., Dyck, P.J., Schmid, H.H. J. Neurochem. (1982) [Pubmed]
  15. Tumor necrosis factor-alpha in immune-mediated demyelination and Wallerian degeneration of the rat peripheral nervous system. Stoll, G., Jung, S., Jander, S., van der Meide, P., Hartung, H.P. J. Neuroimmunol. (1993) [Pubmed]
  16. Regulation of Wallerian degeneration and nerve growth factor withdrawal-induced pruning of axons of sympathetic neurons by the proteasome and the MEK/Erk pathway. MacInnis, B.L., Campenot, R.B. Mol. Cell. Neurosci. (2005) [Pubmed]
  17. Cellular localization of the disintegrin CRII-7/rMDC15 mRNA in rat PNS and CNS and regulated expression in postnatal development and after nerve injury. Bosse, F., Petzold, G., Greiner-Petter, R., Pippirs, U., Gillen, C., Müller, H.W. Glia (2000) [Pubmed]
  18. Cholesterol esterifying enzyme in normal and degenerating peripheral nerve. Yao, J.K., Dyck, P.J. J. Neurochem. (1981) [Pubmed]
  19. Mts1 protein expression in the central nervous system after injury. Kozlova, E.N., Lukanidin, E. Glia (2002) [Pubmed]
  20. An assessment of regeneration across peripheral nerve allografts in rats receiving short courses of cyclosporin A immunosuppression. Mackinnon, S.E., Midha, R., Bain, J., Hunter, D., Wade, J. Neuroscience (1992) [Pubmed]
  21. Transient expression of the neurofilament proteins NF-L and NF-M by Schwann cells is regulated by axonal contact. Fabrizi, C., Kelly, B.M., Gillespie, C.S., Schlaepfer, W.W., Scherer, S.S., Brophy, P.J. J. Neurosci. Res. (1997) [Pubmed]
  22. Sustained induction of heme oxygenase-1 in the traumatized spinal cord. Mautes, A.E., Bergeron, M., Sharp, F.R., Panter, S.S., Weinzierl, M., Guenther, K., Noble, L.J. Exp. Neurol. (2000) [Pubmed]
  23. The number of cells expressing the myelin-supporting oligodendrocyte marker PLP-exon 3b remains unchanged in Wallerian degeneration. Li, G., Blakemore, W.F. J. Neurotrauma (2004) [Pubmed]
  24. Tactile hyperesthesia, altered epidermal innervation and plantar nerve injury in the hindfeet of rats housed on wire grates. Mizisin, A.P., Kalichman, M.W., Garrett, R.S., Dines, K.C. Brain Res. (1998) [Pubmed]
  25. Distribution of calcitonin gene-related peptide in vertebrate neuromuscular junctions: relationship to the acetylcholine receptor. Csillik, B., Tajti, L., Kovács, T., Kukla, E., Rakic, P., Knyihár-Csillik, E. J. Histochem. Cytochem. (1993) [Pubmed]
  26. Tumor necrosis factor receptor 1 and 2 proteins are differentially regulated during Wallerian degeneration of mouse sciatic nerve. George, A., Buehl, A., Sommer, C. Exp. Neurol. (2005) [Pubmed]
  27. Desert hedgehog-patched 2 expression in peripheral nerves during Wallerian degeneration and regeneration. Bajestan, S.N., Umehara, F., Shirahama, Y., Itoh, K., Sharghi-Namini, S., Jessen, K.R., Mirsky, R., Osame, M. J. Neurobiol. (2006) [Pubmed]
  28. Cytokines and peripheral nerve disorders. Créange, A., Barlovatz-Meimon, G., Gherardi, R.K. Eur. Cytokine Netw. (1997) [Pubmed]
  29. Changes in serum growth hormone and prolactin levels, and in hypothalamic growth hormone-releasing hormone, thyrotropin-releasing hormone and somatostatin content, after superior cervical sympathectomy in rats. Cardinalí, D.P., Esquifino, A.I., Arce, A., Vara, E., Ariznavarreta, C., Tresguerres, J.A. Neuroendocrinology (1994) [Pubmed]
  30. Osteopontin: a novel axon-regulated Schwann cell gene. Jander, S., Bussini, S., Neuen-Jacob, E., Bosse, F., Menge, T., Müller, H.W., Stoll, G. J. Neurosci. Res. (2002) [Pubmed]
  31. Expression of genes encoding receptors for IgG (FcRIII) and for C3b/C4b (Crry) in rat sciatic nerve during development and Wallerian degeneration. Vedeler, C.A., Conti, G., Bannerman, P., Pleasure, D. J. Neurosci. Res. (1992) [Pubmed]
  32. Segregation of the intra- and extrahypothalamic neuropeptide Y and catecholaminergic inputs on paraventricular neurons, including those producing thyrotropin-releasing hormone. Diano, S., Naftolin, F., Goglia, F., Horvath, T.L. Regul. Pept. (1998) [Pubmed]
  33. Hypothalamic luteinizing hormone-releasing hormone content and serum luteinizing hormone levels in male rats during wallerian degeneration of sympathetic nerve terminals after superior cervical ganglionectomy. Romeo, H.E., Arias, P., Szwarcfarb, B., Moguilevsky, J.A., Cardinali, D.P. J. Neural Transm. Gen. Sect. (1991) [Pubmed]
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