Chemical Compound Review:
CytoFab (6-carbamimidoylnaphthalen-2- yl) 4...
Synonyms:
Nafamostat, Nafamostatum, CHEMBL273264, SureCN135503, SureCN135504, ...
- Hyperkalemia due to nafamostat mesylate. Kitagawa, H., Chang, H., Fujita, T. N. Engl. J. Med. (1995)
- Effectiveness of nafamostat mesilate on glomerulonephritis in immune-complex diseases. Miyata, T., Fujita, Y., Inagi, R., Inoue, I., Sugiyama, S., Maeda, K. Lancet (1993)
- Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma. Chen, C.L., Wang, S.D., Zeng, Z.Y., Lin, K.J., Kao, S.T., Tani, T., Yu, C.K., Wang, J.Y. J. Allergy Clin. Immunol. (2006)
- Effects of protease inhibitors on replication of various myxoviruses. Hosoya, M., Matsuyama, S., Baba, M., Suzuki, H., Shigeta, S. Antimicrob. Agents Chemother. (1992)
- Depolymerized holothurian glycosaminoglycan (DHG), a novel alternative anticoagulant for hemodialysis, is safe and effective in a dog renal failure model. Minamiguchi, K., Kitazato, K.T., Nagase, H., Sasaki, E., Ohwada, K., Kitazato, K. Kidney Int. (2003)
- Nafamostat mesilate reduces blood loss during open heart surgery. Murase, M., Usui, A., Tomita, Y., Maeda, M., Koyama, T., Abe, T. Circulation (1993)
- Involvement of neutrophil recruitment and protease-activated receptor 2 activation in the induction of IL-18 in mice. Ikawa, K., Nishioka, T., Yu, Z., Sugawara, Y., Kawagoe, J., Takizawa, T., Primo, V., Nikolic, B., Kuroishi, T., Sasano, T., Shimauchi, H., Takada, H., Endo, Y., Sugawara, S. J. Leukoc. Biol. (2005)
- Inhibitory effect of serine protease inhibitors on neutrophil-mediated endothelial cell injury. Nakatani, K., Takeshita, S., Tsujimoto, H., Kawamura, Y., Sekine, I. J. Leukoc. Biol. (2001)
- Can nafamostat mesilate be used for temporary management of hemodialysis in a patient with heparin-induced thrombocytopenia (HIT)? Matsuo, T., Matsuo, M., Ouga-Maruyama, S. Thromb. Haemost. (2001)
- Review article: anti-tryptase therapy in inflammatory bowel disease. Yoshida, N., Isozaki, Y., Takagi, T., Takenaka, S., Uchikawa, R., Arizono, N., Yoshikawa, T., Okanoue, T. Aliment. Pharmacol. Ther. (2006)
- Continuous regional arterial infusion of protease inhibitor and antibiotics in acute necrotizing pancreatitis. Takeda, K., Matsuno, S., Sunamura, M., Kakugawa, Y. Am. J. Surg. (1996)
- Regional effects of nafamostat, a novel potent protease and complement inhibitor, on severe necrotizing pancreatitis. Keck, T., Balcom, J.H., Antoniu, B.A., Lewandrowski, K., Warshaw, A.L., Fernández-del Castillo, C.F. Surgery (2001)
- The effects of nafamostat mesilate (FUT-175) on caerulein-induced acute pancreatitis in the rat. Wisner, J.R., Ozawa, S., Renner, I.G. Int. J. Pancreatol. (1989)
- Cardiac tamponade secondary to hemorrhagic pericarditis during continuous hemofiltration for renal failure. The role of the anticoagulant. Hiraide, A., Tazaki, O., Fujii, N., Yoshioka, T., Sugimoto, T. Renal failure. (1994)
- The influence of a serine protease inhibitor, nafamostat mesilate, on plasma coagulation, and platelet activation during experimental Extracorporeal Life Support (ECLS). Mellgren, K., Skogby, M., Friberg, L.G., Tengborn, L., Wadenvik, H. Thromb. Haemost. (1998)
- Effect of nafamostat mesilate on coagulation and fibrinolysis in hepatic resection. Shimada, M., Matsumata, T., Shirabe, K., Kamakura, T., Taketomi, A., Sugimachi, K. J. Am. Coll. Surg. (1994)
- Effects of nafamostat mesilate and minimal-dose aprotinin on blood-foreign surface interactions in cardiopulmonary bypass. Kaminishi, Y., Hiramatsu, Y., Watanabe, Y., Yoshimura, Y., Sakakibara, Y. Ann. Thorac. Surg. (2004)
- Protective effect of nafamostat mesilate in early wound healing. Tsutamoto, Y., Tani, T., Eguchi, Y., Araki, H., Kodama, M. J. Am. Coll. Surg. (1997)
- Serine proteases are involved in the pathogenesis of trauma-hemorrhagic shock-induced gut and lung injury. Deitch, E.A., Shi, H.P., Lu, Q., Feketeova, E., Xu, d.a. .Z. Shock (2003)
- Nafamostat mesilate, a broad spectrum protease inhibitor, modulates platelet, neutrophil and contact activation in simulated extracorporeal circulation. Sundaram, S., Gikakis, N., Hack, C.E., Niewiarowski, S., Edmunds, L.H., Koneti Rao, A., Sun, L., Cooper, S.L., Colman, R.W. Thromb. Haemost. (1996)
- Elimination of Kupffer cells and nafamostat mesilate rinse prevent reperfusion injury in liver grafts from agonal non-heart-beating donors. Tsukamoto, S., Ohkohchi, N., Fukumori, T., Orii, T., Asakura, T., Takayama, J., Shibuya, H., Kato, H., Satomi, S. Transplantation (1999)
- Role of locally formed angiotensin II and bradykinin in the reduction of myocardial infarct size in dogs. Noda, K., Sasaguri, M., Ideishi, M., Ikeda, M., Arakawa, K. Cardiovasc. Res. (1993)
- Effect of epidermal growth factor on Cu, Zn-superoxide dismutase expression in cultured fibroblasts from rat skin. Nishiguchi, K., Kiyohara, Y., Komada, F., Iwakawa, S., Okumura, K. Pharm. Res. (1994)
- Increased tissue factor pathway inhibitor levels in uremic patients on regular hemodialysis. Kario, K., Matsuo, T., Yamada, T., Matsuo, M. Thromb. Haemost. (1994)
- Detection of intermediary Clr with complete active site, using a synthetic proteinase inhibitor. Niinobe, M., Ueno, Y., Hitomi, Y., Fujii, S. FEBS Lett. (1984)
- A potent tryptase inhibitor nafamostat mesilate dramatically suppressed pulmonary dysfunction induced in rats by a radiographic contrast medium. Sendo, T., Itoh, Y., Goromaru, T., Sumimura, T., Saito, M., Aki, K., Yano, T., Oishi, R. Br. J. Pharmacol. (2003)
- Enhanced bioavailability of subcutaneously injected insulin by pretreatment with ointment containing protease inhibitors. Takeyama, M., Ishida, T., Kokubu, N., Komada, F., Iwakawa, S., Okumura, K., Hori, R. Pharm. Res. (1991)
- Nafamostat mesilate suppresses NF-kappaB activation and NO overproduction in LPS-treated macrophages. Noguchi, S., Nakatsuka, M., Konishi, H., Kamada, Y., Chekir, C., Kudo, T. Int. Immunopharmacol. (2003)
- Nafamostat mesilate induces production of interleukin-12 and -18 in human peripheral blood mononuclear cells. Katsuno, G., Takahashi, H.K., Iwagaki, H., Mizuno, K., Mori, S., Yoshino, T., Nishibori, M., Tanaka, N. J. Pharmacol. Sci. (2005)
- Contribution of anaphylatoxin C5a to late airway responses after repeated exposure of antigen to allergic rats. Abe, M., Shibata, K., Akatsu, H., Shimizu, N., Sakata, N., Katsuragi, T., Okada, H. J. Immunol. (2001)
- The anticoagulant and hemorrhagic effects of DHG, a new depolymerized holothurian glycosaminoglycan, on experimental hemodialysis in dogs. Minamiguchi, K., Kitazato, K.T., Sasaki, E., Nagase, H., Kitazato, K. Thromb. Haemost. (1997)
- Nafamostat mesilate treatment during open heart operation in immune thrombocytopenic purpura. Nakamura, K., Onitsuka, T., Yano, M., Nagahama, H., Nakamura, E., Matsuzaki, Y. Ann. Thorac. Surg. (2000)
- Attenuation of cardiopulmonary bypass-derived inflammatory reactions reduces myocardial reperfusion injury in cardiac operations. Sawa, Y., Shimazaki, Y., Kadoba, K., Masai, T., Fukuda, H., Ohata, T., Taniguchi, K., Matsuda, H. J. Thorac. Cardiovasc. Surg. (1996)