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Chemical Compound Review

Karate     [cyano-(3- phenoxyphenyl)methyl] (1R,3R)-3...

Synonyms: Icon, Cyhalothrin K, CCRIS 8987, PP 321, AC1O5JX6, ...
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Disease relevance of Cyhalothrin K


High impact information on Cyhalothrin K


Chemical compound and disease context of Cyhalothrin K


Biological context of Cyhalothrin K


Anatomical context of Cyhalothrin K


Associations of Cyhalothrin K with other chemical compounds

  • DDT and lambda-cyhalothrin treatment did not reduce the prevalence of malaria episodes as defined by fever (temperatures > or = 37.4 degrees C and/or fever reported) combined with high parasitaemia (> or = 100 parasites/200 leucocytes) [21].
  • Gas chromatography analyses of eight dislodgeable foliar residue (DFR) samples verified mean residues of lambda-cyhalothrin (0.43 +/- 0.10 microg/cm2), propargite (0.35 +/- 0.11 microg/cm2), and sulfur (0.31 +/- 0.28 microg/cm2) on the grape leaves [22].
  • Rate of degradation of lambda-cyhalothrin and methomyl in grapes (Vitis vinifera L.) [23].
  • After 48 h exposure there were only slight increases in mortalities of both species except for increased mortalities for the northern fowl mite with lambda cyhalothrin, amitraz and fenvalerate, and for the chicken mite with amitraz [24].
  • Maximal Accumulated Oxygen Deficit and Blood Responses of Ammonia, Lactate and pH after Anaerobic Test: a Comparison between International and National Elite Karate Athletes [25].

Gene context of Cyhalothrin K

  • These selected larvae were shown to cross-resist to lambda-cyhalothrin as well as to DDT [26].
  • Icon was gavaged daily for 7 consecutive days in three different doses; 63, 83, or 125 mg/kg/day (active ingredient; lambda cyhalothrin; 6.3, 8.3, 12.5 mg/kg/day), respectively [27].

Analytical, diagnostic and therapeutic context of Cyhalothrin K


  1. Letter: Karate myoglobinuria. Russel, S.M., Lewis, A. N. Engl. J. Med. (1975) [Pubmed]
  2. Assessing the impact of Cry1Ab-expressing corn pollen on monarch butterfly larvae in field studies. Stanley-Horn, D.E., Dively, G.P., Hellmich, R.L., Mattila, H.R., Sears, M.K., Rose, R., Jesse, L.C., Losey, J.E., Obrycki, J.J., Lewis, L. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  3. Cytogenetic effects of lambda-cyhalothrin on Wistar rat bone marrow. Celik, A., Mazmanci, B., Camlica, Y., Aşkin, A., Cömelekoglu, U. Mutat. Res. (2003) [Pubmed]
  4. Comparison of laboratory single species and field population-level effects of the pyrethroid insecticide lambda-cyhalothrin on freshwater invertebrates. Schroer, A.F., Belgers, J.D., Brock, T.C., Matser, A.M., Maund, S.J., Van den Brink, P.J. Arch. Environ. Contam. Toxicol. (2004) [Pubmed]
  5. Pyrethroid insecticides and sediment toxicity in urban creeks from California and Tennessee. Amweg, E.L., Weston, D.P., You, J., Lydy, M.J. Environ. Sci. Technol. (2006) [Pubmed]
  6. Protective efficacy of lambda-cyhalothrin treated nets in anopheles gambiae pyrethroid resistance areas of Côte d'Ivoire. Henry, M.C., Assi, S.B., Rogier, C., Dossou-Yovo, J., Chandre, F., Guillet, P., Carnevale, P. Am. J. Trop. Med. Hyg. (2005) [Pubmed]
  7. Evaluation of the genotoxic potential of lambda-cyhalothrin using nuclear and nucleolar biomarkers on fish cells. Cavaş, T., Ergene-Gözükara, S. Mutat. Res. (2003) [Pubmed]
  8. Nested retrotransposons on the W chromosome of the wild silkworm Bombyx mandarina. Abe, H., Sugasaki, T., Terada, T., Kanehara, M., Ohbayashi, F., Shimada, T., Kawai, S., Mita, K., Oshiki, T. Insect Mol. Biol. (2002) [Pubmed]
  9. Third instar nymphs of Rhodnius prolixus exposed to alpha-cyanopyrethroids: from hyperactivity to death. Alzogaray, R.A., Zerba, E.N. Arch. Insect Biochem. Physiol. (2001) [Pubmed]
  10. Effects of pesticides on soil invertebrates in model ecosystem and field studies: a review and comparison with laboratory toxicity data. Jänsch, S., Frampton, G.K., Römbke, J., Van den Brink, P.J., Scott-Fordsmand, J.J. Environ. Toxicol. Chem. (2006) [Pubmed]
  11. Mediation of pyrethroid insecticide toxicity to honey bees (Hymenoptera: Apidae) by cytochrome P450 monooxygenases. Johnson, R.M., Wen, Z., Schuler, M.A., Berenbaum, M.R. J. Econ. Entomol. (2006) [Pubmed]
  12. Susceptibility of adult Coccinella septempunctata (Coleoptera: Coccinellidae) to insecticides with different modes of action. Bozsik, A. Pest Manag. Sci. (2006) [Pubmed]
  13. Field efficacy of fipronil 3G, lambda-cyhalothrin 10%CS, and sumithion 50EC against the dengue vector Aedes albopictus in discarded tires. Sulaiman, S., Pawanchee, Z.A., Wahab, A., Jamal, J., Sohadi, A.R. J. Vector Ecol. (1999) [Pubmed]
  14. Toxicokinetics of lambda-cyhalothrin in rats. Anadón, A., Martínez, M., Martínez, M.A., Díaz, M.J., Martínez-Larrañaga, M.R. Toxicol. Lett. (2006) [Pubmed]
  15. Effects of sub-lethal and lethal doses of lambda-cyhalothrin on oviposition experience and host-searching behaviour of a parasitic wasp, Aphidius ervi. Desneux, N., Pham-Delègue, M.H., Kaiser, L. Pest Manag. Sci. (2004) [Pubmed]
  16. Activity of lambda-cyhalothrin applied as an ultralow volume ground treatment against Anopheles quadrimaculatus adults. Weathersbee, A.A., Meisch, M.V., Inman, A., Dame, D.A. J. Am. Mosq. Control Assoc. (1991) [Pubmed]
  17. Lambda-cyhalothrin-induced changes in oxidative stress biomarkers in rabbit erythrocytes and alleviation effect of some antioxidants. El-Demerdash, F.M. Toxicology in vitro : an international journal published in association with BIBRA (2007) [Pubmed]
  18. Fate of the insecticide lambda-cyhalothrin in ditch enclosures differing in vegetation density. Leistra, M., Zweers, A.J., Warinton, J.S., Crum, S.J., Hand, L.H., Beltman, W.H., Maund, S.J. Pest Manag. Sci. (2004) [Pubmed]
  19. Evaluation of cytogenetic effects of lambda-cyhalothrin on human lymphocytes. Naravaneni, R., Jamil, K. J. Biochem. Mol. Toxicol. (2005) [Pubmed]
  20. Induction of micronuclei by lambda-cyhalothrin in Wistar rat bone marrow and gut epithelial cells. Celik, A., Mazmanci, B., Camlica, Y., Askin, A., Cömelekoglu, U. Mutagenesis (2005) [Pubmed]
  21. The effects of house spraying with DDT or lambda-cyhalothrin against Anopheles arabiensis on measures of malarial morbidity in children in Tanzania. Mnzava, A.E., Rwegoshora, R.T., Tanner, M., Msuya, F.H., Curtis, C.F., Irare, S.G. Acta Trop. (1993) [Pubmed]
  22. Pyrethroid illnesses in California, 1996-2002. Spencer, J., O'Malley, M. Reviews of environmental contamination and toxicology. (2006) [Pubmed]
  23. Rate of degradation of lambda-cyhalothrin and methomyl in grapes (Vitis vinifera L.). Banerjee, K., Upadhyay, A.K., Adsule, P.G., Patil, S.H., Oulkar, D.P., Jadhav, D.R. Food additives and contaminants. (2006) [Pubmed]
  24. Susceptibilities of northern fowl mite, Ornithonyssus sylviarum (Acarina: Macronyssidae), and chicken mite, Dermanyssus gallinae (Acarina: Dermanyssidae), to selected acaricides. Fletcher, M.G., Axtell, R.C. Exp. Appl. Acarol. (1991) [Pubmed]
  25. Maximal Accumulated Oxygen Deficit and Blood Responses of Ammonia, Lactate and pH after Anaerobic Test: a Comparison between International and National Elite Karate Athletes. Ravier, G., Dugu??, B., Grappe, F., Rouillon, J.D. International journal of sports medicine. (2006) [Pubmed]
  26. Pyrethroid tolerance in Culex pipiens pipiens var molestus from Marin County, California. McAbee, R.D., Kang, K.D., Stanich, M.A., Christiansen, J.A., Wheelock, C.E., Inman, A.D., Hammock, B.D., Cornel, A.J. Pest Manag. Sci. (2004) [Pubmed]
  27. Effects of Icon, a pyrethroid insecticide on early pregnancy of rats. Ratnasooriya, W.D., Ratnayake, S.S., Jayatunga, Y.N. Human & experimental toxicology. (2003) [Pubmed]
  28. Spraying houses in the Peruvian Andes with lambda-cyhalothrin protects residents against cutaneous leishmaniasis. Davies, C.R., Llanos-Cuentas, E.A., Campos, P., Monge, J., Leon, E., Canales, J. Trans. R. Soc. Trop. Med. Hyg. (2000) [Pubmed]
  29. Operational note effects of fipronil and lambda-cyhalothrin against larval Anopheles quadrimaculatus and nontarget aquatic mosquito predators in Arkansas small rice plots. Dennett, J.A., Bernhardt, J.L., Meisch, M.V. J. Am. Mosq. Control Assoc. (2003) [Pubmed]
  30. Detection and separation of fenpropathrin, flucythrinate, fluvalinate, and PP 321 by thin-layer chromatography. Khazanchi, R., Handa, S.K. Journal - Association of Official Analytical Chemists. (1989) [Pubmed]
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