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Chemical Compound Review

3-O-Methyl-d-glucose     (2R,3S,4R,5R)-2,4,5,6- tetrahydroxy-3...

Synonyms: Methylglucose, AG-K-77638, CHEBI:73918, CTK0H9772, AR-1F4466, ...
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Disease relevance of 3-O-Methyl-d-glucose


High impact information on 3-O-Methyl-d-glucose


Chemical compound and disease context of 3-O-Methyl-d-glucose

  • Glucose infusion into normal rats produced a similar decrease in 3-O-methylglucose transport constants suggesting that hyperglycemia was responsible for the early decrease in facilitated transport found in the diabetic rats [11].
  • Deoxyglucose and 3-O-methylglucose transport in untreated and ATP-depleted Novikoff rat hepatoma cells. Analysis by a rapid kinetic technique, relationship to phosphorylation and effects of inhibitors [12].
  • S-Trifluoracetonyl-coenzyme A and S-trifluoroacetonylmercaptoethanol form weak to moderately strong complexes with alpha-cyclodextrin and show little or no interaction with the methylglucose polysaccharide and lipopolysaccharides from Mycobacterium smegmatis [Smith, W. L., & Ballou, C. E. (1973) J. Biol. Chem. 248, 7118] [13].
  • Mutants of Mycobacterium smegmatis were selected for resistance to ethionine in an effort to obtain methylation-defective strains that were altered in their ability to make methylmannose polysaccharides (MMP) or methylglucose lipopolysaccharides [14].
  • Vehicle-treated control rats (CR) and rats that were injected with STZ (STZR) after pretreatment with 3-O-methylglucose (3-OMG), an agent that prevents STZ-induced hyperglycemia, were also studied [15].

Biological context of 3-O-Methyl-d-glucose


Anatomical context of 3-O-Methyl-d-glucose


Associations of 3-O-Methyl-d-glucose with other chemical compounds


Gene context of 3-O-Methyl-d-glucose


Analytical, diagnostic and therapeutic context of 3-O-Methyl-d-glucose


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