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Chemical Compound Review

Puromycin aminonucleoside     4-amino-2-(6- dimethylaminopurin-9-yl)-5...

Synonyms: AGN-PC-004VU1, NSC-3056, NSC3056, TimTec1_004068, AC1L1BTI, ...
 
 
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Disease relevance of Aminonucleoside

 

High impact information on Aminonucleoside

 

Chemical compound and disease context of Aminonucleoside

 

Biological context of Aminonucleoside

 

Anatomical context of Aminonucleoside

 

Associations of Aminonucleoside with other chemical compounds

 

Gene context of Aminonucleoside

 

Analytical, diagnostic and therapeutic context of Aminonucleoside

References

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  2. Effect of aminonucleoside nephrosis on immune complex localization in autologous immune complex nephropathy in rats. Couser, W.G., Jermanovich, N.B., Belok, S., Stilmant, M.M., Hoyer, J.R. J. Clin. Invest. (1978) [Pubmed]
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  4. Cloning of the complete biosynthetic gene cluster for an aminonucleoside antibiotic, puromycin, and its regulated expression in heterologous hosts. Lacalle, R.A., Tercero, J.A., Jiménez, A. EMBO J. (1992) [Pubmed]
  5. Altered RNA/protein ratio associated with the induction of differentiation of Friend erythroleukemia cells. Harel, L., Blat, C., Lacour, F., Friend, C. Proc. Natl. Acad. Sci. U.S.A. (1981) [Pubmed]
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  9. Podocyte migration during nephrotic syndrome requires a coordinated interplay between cathepsin L and alpha3 integrin. Reiser, J., Oh, J., Shirato, I., Asanuma, K., Hug, A., Mundel, T.M., Honey, K., Ishidoh, K., Kominami, E., Kreidberg, J.A., Tomino, Y., Mundel, P. J. Biol. Chem. (2004) [Pubmed]
  10. The altered glomerular filtration slits seen in puromycin aminonucleoside nephrosis and protamine sulfate-treated rats contain the tight junction protein ZO-1. Kurihara, H., Anderson, J.M., Kerjaschki, D., Farquhar, M.G. Am. J. Pathol. (1992) [Pubmed]
  11. Renal apolipoproteins in nephrotic rats. van Goor, H., van der Horst, M.L., Atmosoerodjo, J., Joles, J.A., van Tol, A., Grond, J. Am. J. Pathol. (1993) [Pubmed]
  12. Characterization of chronic N,N'-diacetylbenzidine-induced nephropathy. Zimmerman, S.W. Am. J. Pathol. (1979) [Pubmed]
  13. Inhibition of progression of chronic puromycin aminonucleoside nephrosis by probucol, an antioxidant. Magil, A. J. Am. Soc. Nephrol. (1996) [Pubmed]
  14. Cholestyramine resin ameliorates chronic aminonucleoside nephrosis. Diamond, J.R., Hanchak, N.A., McCarter, M.D., Karnovsky, M.J. Am. J. Clin. Nutr. (1990) [Pubmed]
  15. Perinuclear distribution of plectin characterizes visceral epithelial cells of rat glomeruli. Yaoita, E., Wiche, G., Yamamoto, T., Kawasaki, K., Kihara, I. Am. J. Pathol. (1996) [Pubmed]
  16. Modulation of glomerular endothelin and endothelin receptor gene expression in aminonucleoside-induced nephrosis. Nakamura, T., Ebihara, I., Fukui, M., Osada, S., Tomino, Y., Masaki, T., Goto, K., Furuichi, Y., Koide, H. J. Am. Soc. Nephrol. (1995) [Pubmed]
  17. Activation of Galpha q-coupled signaling pathways in glomerular podocytes promotes renal injury. Wang, L., Fields, T.A., Pazmino, K., Dai, Q., Burchette, J.L., Howell, D.N., Coffman, T.M., Spurney, R.F. J. Am. Soc. Nephrol. (2005) [Pubmed]
  18. Reactive oxygen species and antioxidant defense in puromycin aminonucleoside glomerulopathy. Gwinner, W., Landmesser, U., Brandes, R.P., Kubat, B., Plasger, J., Eberhard, O., Koch, K.M., Olbricht, C.J. J. Am. Soc. Nephrol. (1997) [Pubmed]
  19. Puromycin aminonucleoside induces apoptosis and increases HNE in cultured glomerular epithelial cells(1). Suzuki, T., Takemura, H., Noiri, E., Nosaka, K., Toda, A., Taniguchi, S., Uchida, K., Fujita, T., Kimura, S., Nakao, A. Free Radic. Biol. Med. (2001) [Pubmed]
  20. Regional heterogeneity of glycoconjugate distribution in the glomerulus revealed by lectin-gold cytochemistry and SDS-PAGE. Brown, D., Vassalli, J.D., Kunz, A., Mühlhauser, J., Orci, L., Mulhauser, J. Am. J. Pathol. (1986) [Pubmed]
  21. Effects of the aminonucleoside of puromycin on glomerular epithelial cells in vitro. Fishman, J.A., Karnovsky, M.J. Am. J. Pathol. (1985) [Pubmed]
  22. Glomerular basement membrane anionic charge site changes early in aminonucleoside nephrosis. Mahan, J.D., Sisson-Ross, S., Vernier, R.L. Am. J. Pathol. (1986) [Pubmed]
  23. Glomerular permselectivity factors are not responsible for the increase in fractional clearance of albumin in rat glomerulonephritis. Greive, K.A., Nikolic-Paterson, D.J., Guimarães, M.A., Nikolovski, J., Pratt, L.M., Mu, W., Atkins, R.C., Comper, W.D. Am. J. Pathol. (2001) [Pubmed]
  24. Renal extracellular matrix accumulation in acute puromycin aminonucleoside nephrosis in rats. Jones, C.L., Buch, S., Post, M., McCulloch, L., Liu, E., Eddy, A.A. Am. J. Pathol. (1992) [Pubmed]
  25. Co-localization of nephrin, podocin, and the actin cytoskeleton: evidence for a role in podocyte foot process formation. Saleem, M.A., Ni, L., Witherden, I., Tryggvason, K., Ruotsalainen, V., Mundel, P., Mathieson, P.W. Am. J. Pathol. (2002) [Pubmed]
  26. Contribution of mononuclear leucocytes to the progression of experimental focal glomerular sclerosis. Saito, T., Atkins, R.C. Kidney Int. (1990) [Pubmed]
  27. Prostaglandin E2 promotes cell survival of glomerular epithelial cells via the EP4 receptor. Aoudjit, L., Potapov, A., Takano, T. Am. J. Physiol. Renal Physiol. (2006) [Pubmed]
  28. Modulation of cyclic AMP levels and differentiation by adenosine analogs in mouse erythroleukemia cells. Sherman, M.L., Shafman, T.D., Kufe, D.W. J. Cell. Physiol. (1988) [Pubmed]
  29. Puromycin analogues. Effect of aryl-substituted puromycin analogues on the ribosomal peptidyltransferase reaction. Lee, H., Fong, K.L., Vince, R. J. Med. Chem. (1981) [Pubmed]
  30. The cyclin-dependent kinase inhibitor p21 is required for TGF-beta1-induced podocyte apoptosis. Wada, T., Pippin, J.W., Terada, Y., Shankland, S.J. Kidney Int. (2005) [Pubmed]
  31. Downregulation of vascular endothelial growth factor and its receptors in the kidney in rats with puromycin aminonucleoside nephrosis. Fan, L., Wakayama, T., Yokoyama, S., Amano, O., Iseki, S. Nephron (2002) [Pubmed]
  32. Podocyte flattening and disorder of glomerular basement membrane are associated with splitting of dystroglycan-matrix interaction. Kojima, K., Davidovits, A., Poczewski, H., Langer, B., Uchida, S., Nagy-Bojarski, K., Hovorka, A., Sedivy, R., Kerjaschki, D. J. Am. Soc. Nephrol. (2004) [Pubmed]
  33. Thrombospondin 1 precedes and predicts the development of tubulointerstitial fibrosis in glomerular disease in the rat. Hugo, C., Shankland, S.J., Pichler, R.H., Couser, W.G., Johnson, R.J. Kidney Int. (1998) [Pubmed]
  34. Decay-accelerating factor expression in the rat kidney is restricted to the apical surface of podocytes. Bao, L., Spiller, O.B., St John, P.L., Haas, M., Hack, B.K., Ren, G., Cunningham, P.N., Doshi, M., Abrahamson, D.R., Morgan, B.P., Quigg, R.J. Kidney Int. (2002) [Pubmed]
  35. Focal and segmental glomerulosclerosis following a single intravenous dose of puromycin aminonucleoside. Diamond, J.R., Karnovsky, M.J. Am. J. Pathol. (1986) [Pubmed]
  36. Failure of angiotensin converting enzyme inhibition to affect the course of chronic puromycin aminonucleoside nephropathy. Marinides, G.N., Groggel, G.C., Cohen, A.H., Cook, T., Baranowski, R.L., Westenfelder, C., Border, W.A. Am. J. Pathol. (1987) [Pubmed]
  37. Hepatic HMG-CoA reductase gene expression during the course of puromycin-induced nephrosis. Vaziri, N.D., Liang, K.H. Kidney Int. (1995) [Pubmed]
  38. Retinoids in nephrology: promises and pitfalls. Xu, Q., Lucio-Cazana, J., Kitamura, M., Ruan, X., Fine, L.G., Norman, J.T. Kidney Int. (2004) [Pubmed]
  39. Expression of allograft inflammatory factor-1 in kidneys: A novel molecular component of podocyte. Tsubata, Y., Sakatsume, M., Ogawa, A., Alchi, B., Kaneko, Y., Kuroda, T., Kawachi, H., Narita, I., Yamamoto, T., Gejyo, F. Kidney Int. (2006) [Pubmed]
 
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