- Proteinase-activated receptors 1 and 4 counter-regulate endostatin and VEGF release from human platelets. Ma, L., Perini, R., McKnight, W., Dicay, M., Klein, A., Hollenberg, M.D., Wallace, J.L. Proc. Natl. Acad. Sci. U.S.A. (2005)
- PAR4, but not PAR1, signals human platelet aggregation via Ca2+ mobilization and synergistic P2Y12 receptor activation. Holinstat, M., Voss, B., Bilodeau, M.L., McLaughlin, J.N., Cleator, J., Hamm, H.E. J. Biol. Chem. (2006)
- PAR1-mediated NFkappaB activation promotes survival of prostate cancer cells through a Bcl-xL-dependent mechanism. Tantivejkul, K., Loberg, R.D., Mawocha, S.C., Day, L.L., John, L.S., Pienta, B.A., Rubin, M.A., Pienta, K.J. J. Cell. Biochem. (2005)
- Protease-activated receptor 1: a role in prostate cancer metastasis. Yuan, T.C., Lin, M.F. Clinical prostate cancer. (2004)
- PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells. Boire, A., Covic, L., Agarwal, A., Jacques, S., Sherifi, S., Kuliopulos, A. Cell (2005)
- Intense and highly localized gene conversion activity in human meiotic crossover hot spots. Jeffreys, A.J., May, C.A. Nat. Genet. (2004)
- Crossover clustering and rapid decay of linkage disequilibrium in the Xp/Yp pseudoautosomal gene SHOX. May, C.A., Shone, A.C., Kalaydjieva, L., Sajantila, A., Jeffreys, A.J. Nat. Genet. (2002)
- Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury. Jenkins, R.G., Su, X., Su, G., Scotton, C.J., Camerer, E., Laurent, G.J., Davis, G.E., Chambers, R.C., Matthay, M.A., Sheppard, D. J. Clin. Invest. (2006)
- Injury-related factors and conditions down-regulate the thrombin receptor (PAR-1) in a human neuronal cell line. Weinstein, J.R., Lau, A.L., Brass, L.F., Cunningham, D.D. J. Neurochem. (1998)
- A novel PAR-1-type thrombin receptor signaling pathway: cyclic AMP-independent activation of PKA in SNB-19 glioblastoma cells. Zieger, M., Tausch, S., Henklein, P., Nowak, G., Kaufmann, R. Biochem. Biophys. Res. Commun. (2001)
- Thalidomide protects endothelial cells from doxorubicin-induced apoptosis but alters cell morphology. Kaushal, V., Kaushal, G.P., Melkaveri, S.N., Mehta, P. J. Thromb. Haemost. (2004)
- Protease-activated receptor-1 in human brain: localization and functional expression in astrocytes. Junge, C.E., Lee, C.J., Hubbard, K.B., Zhang, Z., Olson, J.J., Hepler, J.R., Brat, D.J., Traynelis, S.F. Exp. Neurol. (2004)
- Mutation and deletion of the pseudoautosomal gene SHOX cause Leri-Weill dyschondrosteosis. Shears, D.J., Vassal, H.J., Goodman, F.R., Palmer, R.W., Reardon, W., Superti-Furga, A., Scambler, P.J., Winter, R.M. Nat. Genet. (1998)
- Akt activation in platelets depends on Gi signaling pathways. Kim, S., Jin, J., Kunapuli, S.P. J. Biol. Chem. (2004)
- Protease-activated receptors 1 and 4 mediate thrombin signaling in endothelial cells. Kataoka, H., Hamilton, J.R., McKemy, D.D., Camerer, E., Zheng, Y.W., Cheng, A., Griffin, C., Coughlin, S.R. Blood (2003)
- Inactivation of protease-activated receptor-1 by proteolytic removal of the ligand region in vascular endothelial cells. Nakayama, T., Hirano, K., Hirano, M., Nishimura, J., Kuga, H., Nakamura, K., Takahashi, S., Kanaide, H. Biochem. Pharmacol. (2004)
- PAR1-type thrombin receptor stimulates migration and matrix adhesion of human colon carcinoma cells by a PKCepsilon-dependent mechanism. Heider, I., Schulze, B., Oswald, E., Henklein, P., Scheele, J., Kaufmann, R. Oncol. Res. (2004)
- Protease-activated receptor (PAR) 1 but not PAR2 or PAR4 mediates endothelium-dependent relaxation to thrombin and trypsin in human pulmonary arteries. Hamilton, J.R., Moffatt, J.D., Frauman, A.G., Cocks, T.M. J. Cardiovasc. Pharmacol. (2001)
- Protease-activated receptors 1 and 4 do not stimulate G(i) signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of G(i) signaling. Kim, S., Foster, C., Lecchi, A., Quinton, T.M., Prosser, D.M., Jin, J., Cattaneo, M., Kunapuli, S.P. Blood (2002)
- The effects of dexamethasone and dehydroepiandrosterone (DHEA) on cytokines and receptor expression in a human osteoblastic cell line: Potential steroid-sparing role for DHEA. Harding, G., Mak, Y.T., Evans, B., Cheung, J., Macdonald, D., Hampson, G. Cytokine (2006)
- Inhibition of thrombin-induced vascular endothelial growth factor production in human neuroblastoma (NB-1) cells by argatroban. Sarker, K.P., Biswas, K.K., Yamaji, K., Yamakuchi, M., Hashiguchi, T., Lee, K.Y., Maruyama, I. Pathophysiol. Haemost. Thromb. (2005)
- Protease-activated receptors 1 and 4 are shut off with distinct kinetics after activation by thrombin. Shapiro, M.J., Weiss, E.J., Faruqi, T.R., Coughlin, S.R. J. Biol. Chem. (2000)
- Protease-activated receptor-1 down-regulation: a mutant HeLa cell line suggests novel requirements for PAR1 phosphorylation and recruitment to clathrin-coated pits. Trejo, J., Altschuler, Y., Fu, H.W., Mostov, K.E., Coughlin, S.R. J. Biol. Chem. (2000)
- Analysis of imprinted genes in subjects with Prader-Willi syndrome and chromosome 15 abnormalities. Muralidhar, B., Marney, A., Butler, M.G. Genet. Med. (1999)
- Short arm rearrangements of sex chromosomes with haploinsufficiency of the SHOX gene are associated with Leri-Weill dyschondrosteosis. Palka, G., Stuppia, L., Guanciali Franchi, P., Chiarelli, F., Fischetto, R., Borrelli, P., Giannotti, A., Fioretti, G., Rinaldi, M.M., Mingarelli, R., Rappold, G.A., Calabrese, G. Clin. Genet. (2000)
- Gene duplications as a recurrent theme in the evolution of the human pseudoautosomal region 1: isolation of the gene ASMTL. Ried, K., Rao, E., Schiebel, K., Rappold, G.A. Hum. Mol. Genet. (1998)
- Structure and chromosomal localization of the human glycogenin-2 gene GYG2. Zhai, L., Mu, J., Zong, H., DePaoli-Roach, A.A., Roach, P.J. Gene (2000)
- Tumor cell invasion is promoted by activation of protease activated receptor-1 in cooperation with the alpha vbeta 5 integrin. Even-Ram, S.C., Maoz, M., Pokroy, E., Reich, R., Katz, B.Z., Gutwein, P., Altevogt, P., Bar-Shavit, R. J. Biol. Chem. (2001)
- Expression of protease activated receptor 3 (PAR3) is upregulated by induction of megakaryocyte phenotype in human erythroleukemia (HEL) cells. Cupit, L.D., Schmidt, V.A., Gnatenko, D.V., Bahou, W.F. Exp. Hematol. (2004)