Gene Review:
Il10 - interleukin 10
Rattus norvegicus
Synonyms:
CSIF, Cytokine synthesis inhibitory factor, IL-10, Il-10, Interleukin-10
- Interleukin-10 produced by recombinant adenovirus prolongs survival of cardiac allografts in rats. David, A., Chétritt, J., Guillot, C., Tesson, L., Heslan, J.M., Cuturi, M.C., Soulillou, J.P., Anegon, I. Gene Ther. (2000)
- Kupffer cell cytokines interleukin-1beta and interleukin-10 combine to inhibit phosphoenolpyruvate carboxykinase and gluconeogenesis in cultured hepatocytes. Yerkovich, S.T., Rigby, P.J., Fournier, P.A., Olynyk, J.K., Yeoh, G.C. Int. J. Biochem. Cell Biol. (2004)
- Cytokines in relapsing experimental autoimmune encephalomyelitis in DA rats: persistent mRNA expression of proinflammatory cytokines and absent expression of interleukin-10 and transforming growth factor-beta. Issazadeh, S., Lorentzen, J.C., Mustafa, M.I., Höjeberg, B., Müssener, A., Olsson, T. J. Neuroimmunol. (1996)
- Sequential expression of mRNA for proinflammatory cytokines and interleukin-10 in the rat peripheral nervous system: comparison between immune-mediated demyelination and Wallerian degeneration. Gillen, C., Jander, S., Stoll, G. J. Neurosci. Res. (1998)
- Significance of changes in TNF-alpha and IL-10 levels in the progression of heart failure subsequent to myocardial infarction. Kaur, K., Sharma, A.K., Singal, P.K. Am. J. Physiol. Heart Circ. Physiol. (2006)
- Central injection of IL-10 antagonizes the behavioural effects of lipopolysaccharide in rats. Bluthé, R.M., Castanon, N., Pousset, F., Bristow, A., Ball, C., Lestage, J., Michaud, B., Kelley, K.W., Dantzer, R. Psychoneuroendocrinology (1999)
- Betamethasone Affects Cerebral Expressions of NF-{kappa}B and Cytokines that Correlate with Pain Behavior in a Rat Model of Neuropathy. Xie, W., Luo, S., Xuan, H., Chou, C., Song, G., Lv, R., Jin, Y., Li, W., Xu, J. Ann. Clin. Lab. Sci. (2006)
- The effect of interleukin-10 on acute pancreatitis induced by cerulein in a rat experimental model. Keceli, M., Kucuk, C., Sozuer, E., Kerek, M., Ince, O., Arar, M. Journal of investigative surgery : the official journal of the Academy of Surgical Research. (2005)
- Tolerance is dependent on complement C3 fragment iC3b binding to antigen-presenting cells. Sohn, J.H., Bora, P.S., Suk, H.J., Molina, H., Kaplan, H.J., Bora, N.S. Nat. Med. (2003)
- Sympathetic activation triggers systemic interleukin-10 release in immunodepression induced by brain injury. Woiciechowsky, C., Asadullah, K., Nestler, D., Eberhardt, B., Platzer, C., Schöning, B., Glöckner, F., Lanksch, W.R., Volk, H.D., Döcke, W.D. Nat. Med. (1998)
- Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity. Stumbles, P.A., Thomas, J.A., Pimm, C.L., Lee, P.T., Venaille, T.J., Proksch, S., Holt, P.G. J. Exp. Med. (1998)
- The effects of interleukin-10 in hemorrhagic shock. Karakozis, S., Hinds, M., Cook, J.W., Kim, D., Provido, H., Kirkpatrick, J.R. J. Surg. Res. (2000)
- Effect of ketamine on cocaine-induced immunotoxicity in rats. Rofael, H.Z., Turkall, R.M., Abdel-Rahman, M.S. International journal of toxicology. (2003)
- Interleukin-10 overexpression mediates phenyl-N-tert-butyl nitrone protection from endotoxemia. Kotake, Y., Sang, H., Tabatabaie, T., Wallis, G.L., Moore, D.R., Stewart, C.A. Shock (2002)
- Effects of ketamine and propofol on the ratio of interleukin-6 to interleukin-10 during endotoxemia in rats. Taniguchi, T., Kanakura, H., Takemoto, Y., Kidani, Y., Yamamoto, K. Tohoku J. Exp. Med. (2003)
- The inhibitory effect of interleukin-10 on mouse osteoclast formation involves novel tyrosine-phosphorylated proteins. Hong, M.H., Williams, H., Jin, C.H., Pike, J.W. J. Bone Miner. Res. (2000)
- Kupffer cells modulate splenic interleukin-10 production in endotoxin-induced liver injury after partial hepatectomy. Kurachi, K., Suzuki, S., Sakaguchi, T., Yokoi, Y., Konno, H., Baba, S., Nakamura, S. J. Hepatol. (2003)
- Tumor necrosis factor-alpha activates signal transduction in hypothalamus and modulates the expression of pro-inflammatory proteins and orexigenic/anorexigenic neurotransmitters. Amaral, M.E., Barbuio, R., Milanski, M., Romanatto, T., Barbosa, H.C., Nadruz, W., Bertolo, M.B., Boschero, A.C., Saad, M.J., Franchini, K.G., Velloso, L.A. J. Neurochem. (2006)
- In vivo suppression of NF-kappa B and preservation of I kappa B alpha by interleukin-10 and interleukin-13. Lentsch, A.B., Shanley, T.P., Sarma, V., Ward, P.A. J. Clin. Invest. (1997)
- A Regulatory CD4+ T Cell Subset in the BB Rat Model of Autoimmune Diabetes Expresses Neither CD25 Nor Foxp3. Hillebrands, J.L., Whalen, B., Visser, J.T., Koning, J., Bishop, K.D., Leif, J., Rozing, J., Mordes, J.P., Greiner, D.L., Rossini, A.A. J. Immunol. (2006)
- Inflammatory and anti-inflammatory cytokines regulate the recovery from sublethal X irradiation in rat thymus. Mizutani, N., Fujikura, Y., Wang, Y.H., Tamechika, M., Tokuda, N., Sawada, T., Fukumoto, T. Radiat. Res. (2002)
- Endogenous interleukin-10 is required for the defervescence of fever evoked by local lipopolysaccharide-induced and Staphylococcus aureus-induced inflammation in rats. Cartmell, T., Ball, C., Bristow, A.F., Mitchell, D., Poole, S. J. Physiol. (Lond.) (2003)
- Thalidomide treatment in chronic constrictive neuropathy decreases endoneurial tumor necrosis factor-alpha, increases interleukin-10 and has long-term effects on spinal cord dorsal horn met-enkephalin. George, A., Marziniak, M., Schäfers, M., Toyka, K.V., Sommer, C. Pain (2000)
- Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase. Pahan, K., Khan, M., Singh, I. J. Neurochem. (2000)
- Tacrolimus and cyclosporine differ in their capacity to overcome ongoing allograft rejection as a result of their differential abilities to inhibit interleukin-10 production. Jiang, H., Wynn, C., Pan, F., Ebbs, A., Erickson, L.M., Kobayashi, M. Transplantation (2002)
- Interleukin-10 receptor signaling through STAT-3 regulates the apoptosis of retinal ganglion cells in response to stress. Boyd, Z.S., Kriatchko, A., Yang, J., Agarwal, N., Wax, M.B., Patil, R.V. Invest. Ophthalmol. Vis. Sci. (2003)
- Dysregulated luminal bacterial antigen-specific T-cell responses and antigen-presenting cell function in HLA-B27 transgenic rats with chronic colitis. Qian, B.F., Tonkonogy, S.L., Hoentjen, F., Dieleman, L.A., Sartor, R.B. Immunology (2005)
- Attenuation of ozone-induced lung injury by interleukin-10. Reinhart, P.G., Gupta, S.K., Bhalla, D.K. Toxicol. Lett. (1999)
- Interleukin (IL)-10 inhibits long-term IL-6 production but not preformed mediator release from rat peritoneal mast cells. Marshall, J.S., Leal-Berumen, I., Nielsen, L., Glibetic, M., Jordana, M. J. Clin. Invest. (1996)
- Intercellular adhesion molecule-1 gene expression by glial cells. Differential mechanisms of inhibition by IL-10 and IL-6. Shrikant, P., Weber, E., Jilling, T., Benveniste, E.N. J. Immunol. (1995)
- Phenotypic and functional characterization of vaginal dendritic cells in a rat model of Candida albicans vaginitis. De Bernardis, F., Lucciarini, R., Boccanera, M., Amantini, C., Arancia, S., Morrone, S., Mosca, M., Cassone, A., Santoni, G. Infect. Immun. (2006)
- Interleukin-10, interleukin-4, and transforming growth factor-beta differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells. Ledeboer, A., Brevé, J.J., Poole, S., Tilders, F.J., Van Dam, A.M. Glia (2000)