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SERPINA1  -  serpin peptidase inhibitor, clade A (alpha...

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Disease relevance of SERPINA1

 

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Biological context of SERPINA1

 

Anatomical context of SERPINA1

 

Associations of SERPINA1 with chemical compounds

 

Other interactions of SERPINA1

 

Analytical, diagnostic and therapeutic context of SERPINA1

References

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  2. Characterization of a 54 kDa, alpha 1-antitrypsin-like protein isolated from ascitic fluid of an endometrial cancer patient. Tanaka, N., Sekiya, S., Takamizawa, H., Kato, N., Moriyama, Y., Fujimura, S. Jpn. J. Cancer Res. (1991) [Pubmed]
  3. Milk trypsin-inhibitor capacity as an indicator of bovine mastitis--a novel principle which can be automated. Sandholm, M., Honkanen-Buzalski, T., Kangasniemi, R. J. Dairy Res. (1984) [Pubmed]
  4. Acute phase response in heifers with experimentally induced mastitis. Hirvonen, J., Pyörälä, S., Jousimies-Somer, H. J. Dairy Res. (1996) [Pubmed]
  5. Release of fibronectin, sulfated glycosaminoglycans and beta-hexosaminidase from injured smooth muscle cells and fibroblasts in culture--possible transferable effects on new cultures. Stavenow, L., Hultberg, B. Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology. (1985) [Pubmed]
  6. Tissue-specific gene expression in mouse hepatocytes cultured in growth-restricting medium. Spiegelberg, T., Bishop, J.O. Mol. Cell. Biol. (1988) [Pubmed]
  7. Alpha 1-acid glycoprotein and alpha 1-antitrypsin inhibit TNF-induced but not anti-Fas-induced apoptosis of hepatocytes in mice. Van Molle, W., Libert, C., Fiers, W., Brouckaert, P. J. Immunol. (1997) [Pubmed]
  8. Role of the catalytic serine in the interactions of serine proteinases with protein inhibitors of the serpin family. Contribution of a covalent interaction to the binding energy of serpin-proteinase complexes. Olson, S.T., Bock, P.E., Kvassman, J., Shore, J.D., Lawrence, D.A., Ginsburg, D., Björk, I. J. Biol. Chem. (1995) [Pubmed]
  9. Preparation and characterization of latent alpha 1-antitrypsin. Lomas, D.A., Elliott, P.R., Chang, W.S., Wardell, M.R., Carrell, R.W. J. Biol. Chem. (1995) [Pubmed]
  10. Demonstration of a calcium requirement for secretory protein processing and export. Differential effects of calcium and dithiothreitol. Kuznetsov, G., Brostrom, M.A., Brostrom, C.O. J. Biol. Chem. (1992) [Pubmed]
  11. Complete cDNA sequence of bovine alpha 1-antitrypsin. Sinha, D., Bakhshi, M.R., Kirby, E.P. Biochim. Biophys. Acta (1992) [Pubmed]
  12. The transcription factor LF-A1 interacts with a bipartite recognition sequence in the promoter regions of several liver-specific genes. Ramji, D.P., Tadros, M.H., Hardon, E.M., Cortese, R. Nucleic Acids Res. (1991) [Pubmed]
  13. Crystal structure of cleaved bovine antithrombin III at 3.2 A resolution. Mourey, L., Samama, J.P., Delarue, M., Petitou, M., Choay, J., Moras, D. J. Mol. Biol. (1993) [Pubmed]
  14. Weaning to hypoallergenic formula improves gut barrier function in breast-fed infants with atopic eczema. Arvola, T., Moilanen, E., Vuento, R., Isolauri, E. J. Pediatr. Gastroenterol. Nutr. (2004) [Pubmed]
  15. Hexa- and pentapeptide extension of proalbumin: feedback inhibition of albumin synthesis by its propeptide in isolated hepatocytes and in the cell-free system. Weigand, K., Schmid, M., Villringer, A., Birr, C., Heinrich, P.C. Biochemistry (1982) [Pubmed]
  16. Anti-pneumolysin activity of commercially available alpha 1-antitrypsin is due to cholesterol impurities. Rubins, J.B., Freiberg, M.R. Microb. Pathog. (1994) [Pubmed]
  17. Efficacy of serine protease inhibitors against Cryptosporidium parvum infection in a bovine fallopian tube epithelial cell culture system. Forney, J.R., Yang, S., Du, C., Healey, M.C. J. Parasitol. (1996) [Pubmed]
  18. Interference of cartilage surface with interaction of granulocyte elastase with alpha 1-proteinase inhibitor. An in vitro model of enzyme inhibition in the joint space. Burkhardt, H., Kasten, M., Rauls, S., Rehkopf, E. Rheumatol. Int. (1987) [Pubmed]
  19. Role of a membrane-associated serine esterase in the oxidant activation of phospholipase A2 by t-butyl hydroperoxide. Chakraborti, S., Michael, J.R., Gurtner, G.H., Ghosh, S.S., Dutta, G., Merker, A. Biochem. J. (1993) [Pubmed]
  20. Synergistic anticryptosporidial potential of the combination alpha-1-antitrypsin and paromomycin. Forney, J.R., Yang, S., Healey, M.C. Antimicrob. Agents Chemother. (1997) [Pubmed]
  21. Purification and characterization of an enzyme produced by Treponema denticola capable of hydrolyzing synthetic trypsin substrates. Ohta, K., Makinen, K.K., Loesche, W.J. Infect. Immun. (1986) [Pubmed]
  22. Cleavage of proteins of reproductive secretions by extracellular proteinases of Tritrichomonas foetus. Talbot, J.A., Nielsen, K., Corbeil, L.B. Can. J. Microbiol. (1991) [Pubmed]
  23. On the influence of the substrate (elastin) in elastase-alpha 1 antitrypsin interactions. Hornebeck, W., Soleilhac, J.M., Velebny, V., Robert, L. Pathol. Biol. (1985) [Pubmed]
  24. Cloning of fibrinogen, prothrombin, and alpha 1-antitrypsin. Davie, E.W. Harvey Lect. (1981) [Pubmed]
  25. Kinetic dissection of alpha 1-antitrypsin inhibition mechanism. Shin, J.S., Yu, M.H. J. Biol. Chem. (2002) [Pubmed]
  26. Isolation, chemical, and physical properties of alpha-1-antitrypsin. Musiani, P., Tomasi, T.B. Biochemistry (1976) [Pubmed]
  27. Differences between the binding of trypsin and chymotrypsin by alpha 1-proteinase inhibitor. Hercz, A. Biochem. Biophys. Res. Commun. (1986) [Pubmed]
  28. Effective cryopreservation and long-term storage of primary human hepatocytes with recovery of viability, differentiation, and replicative potential. Adams, R.M., Wang, M., Crane, A.M., Brown, B., Darlington, G.J., Ledley, F.D. Cell transplantation. (1995) [Pubmed]
 
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