Gene Review:
Ctf1 - cardiotrophin 1
Rattus norvegicus
Synonyms:
CT-1, Cardiotrophin-1
- Adenoviral gene transfer of GDNF, BDNF and TGF beta 2, but not CNTF, cardiotrophin-1 or IGF1, protects injured adult motoneurons after facial nerve avulsion. Sakamoto, T., Kawazoe, Y., Shen, J.S., Takeda, Y., Arakawa, Y., Ogawa, J., Oyanagi, K., Ohashi, T., Watanabe, K., Inoue, K., Eto, Y., Watabe, K. J. Neurosci. Res. (2003)
- Cardiotrophin-1 and urocortin cause protection by the same pathway and hypertrophy via distinct pathways in cardiac myocytes. Railson, J.E., Liao, Z., Brar, B.K., Buddle, J.C., Pennica, D., Stephanou, A., Latchman, D.S. Cytokine (2002)
- Synaptic targeting of retrogradely transported trophic factors in motoneurons: comparison of glial cell line-derived neurotrophic factor, brain-derived neurotrophic factor, and cardiotrophin-1 with tetanus toxin. Rind, H.B., Butowt, R., von Bartheld, C.S. J. Neurosci. (2005)
- Increased expression of IL-6 and LIF in the hypertrophied left ventricle of TGR(mRen2)27 and SHR rats. Kurdi, M., Randon, J., Cerutti, C., Bricca, G. Mol. Cell. Biochem. (2005)
- Differential hypertrophic effects of cardiotrophin-1 on adult cardiomyocytes from normotensive and spontaneously hypertensive rats. L??pez, N., D??ez, J., Fortu??o, M.A. J. Mol. Cell. Cardiol. (2006)
- Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy. Pennica, D., King, K.L., Shaw, K.J., Luis, E., Rullamas, J., Luoh, S.M., Darbonne, W.C., Knutzon, D.S., Yen, R., Chien, K.R. Proc. Natl. Acad. Sci. U.S.A. (1995)
- Interplay among cardiotrophin-1, prostaglandins, and vascular endothelial growth factor in rat liver regeneration. Beraza, N., Marqués, J.M., Martínez-Ansó, E., Iñiguez, M., Prieto, J., Bustos, M. Hepatology (2005)
- Cardiotrophin-1 attenuates endotoxin-induced acute lung injury. Pulido, E.J., Shames, B.D., Pennica, D., O'leary, R.M., Bensard, D.D., Cain, B.S., McIntyre, R.C. J. Surg. Res. (1999)
- Cardiotrophin-1 increases angiotensinogen mRNA in rat cardiac myocytes through STAT3 : an autocrine loop for hypertrophy. Fukuzawa, J., Booz, G.W., Hunt, R.A., Shimizu, N., Karoor, V., Baker, K.M., Dostal, D.E. Hypertension (2000)
- Prostaglandin F2 alpha induces cardiac myocyte hypertrophy in vitro and cardiac growth in vivo. Lai, J., Jin, H., Yang, R., Winer, J., Li, W., Yen, R., King, K.L., Zeigler, F., Ko, A., Cheng, J., Bunting, S., Paoni, N.F. Am. J. Physiol. (1996)
- The cytoprotective effects of the glycoprotein 130 receptor-coupled cytokine, cardiotrophin-1, require activation of NF-kappa B. Craig, R., Wagner, M., McCardle, T., Craig, A.G., Glembotski, C.C. J. Biol. Chem. (2001)
- Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes. Takahashi, N., Saito, Y., Kuwahara, K., Harada, M., Tanimoto, K., Nakagawa, Y., Kawakami, R., Nakanishi, M., Yasuno, S., Usami, S., Yoshimura, A., Nakao, K. J. Mol. Cell. Cardiol. (2005)
- Synergistic effects of schwann- and muscle-derived factors on motoneuron survival involve GDNF and cardiotrophin-1 (CT-1). Arce, V., Pollock, R.A., Philippe, J.M., Pennica, D., Henderson, C.E., deLapeyrière, O. J. Neurosci. (1998)
- Differential regulation of cytokine expression following pilocarpine-induced seizure. Jankowsky, J.L., Patterson, P.H. Exp. Neurol. (1999)
- Cardiotrophin-1: expression in experimental myocardial infarction and potential role in post-MI wound healing. Freed, D.H., Moon, M.C., Borowiec, A.M., Jones, S.C., Zahradka, P., Dixon, I.M. Mol. Cell. Biochem. (2003)
- Teratogenic effects of bis-diamine on the developing myocardium. Okamoto, N., Nakagawa, M., Fujino, H., Nishijima, S., Hanato, T., Narita, T., Takeuchi, Y., Imanaka-Yoshida, K. Birth defects research. Part A, Clinical and molecular teratology. (2004)
- Effects of cardiotrophin on adipocytes. Zvonic, S., Hogan, J.C., Arbour-Reily, P., Mynatt, R.L., Stephens, J.M. J. Biol. Chem. (2004)
- SOCS1/JAB likely mediates the protective effect of cardiotrophin-1 against lipopolysaccharide-induced left ventricular dysfunction in vivo. Tanimoto, K., Saito, Y., Hamanaka, I., Kuwahara, K., Harada, M., Takahashi, N., Kawakami, R., Nakagawa, Y., Nakanishi, M., Adachi, Y., Shirakami, G., Fukuda, K., Yoshimura, A., Nakao, K. Circ. J. (2005)
- Suppression of hippocampal plasticity-related gene expression by sleep deprivation in rats. Guzman-Marin, R., Ying, Z., Suntsova, N., Methippara, M., Bashir, T., Szymusiak, R., Gomez-Pinilla, F., McGinty, D. J. Physiol. (Lond.) (2006)
- Cardiotrophin-1, a cytokine present in embryonic muscle, supports long-term survival of spinal motoneurons. Pennica, D., Arce, V., Swanson, T.A., Vejsada, R., Pollock, R.A., Armanini, M., Dudley, K., Phillips, H.S., Rosenthal, A., Kato, A.C., Henderson, C.E. Neuron (1996)
- Involvement of gp130-mediated signaling in pressure overload-induced activation of the JAK/STAT pathway in rodent heart. Pan, J., Fukuda, K., Kodama, H., Sano, M., Takahashi, T., Makino, S., Kato, T., Manabe, T., Hori, S., Ogawa, S. Heart and vessels. (1998)
- Cardiotrophin-1. Biological activities and binding to the leukemia inhibitory factor receptor/gp130 signaling complex. Pennica, D., Shaw, K.J., Swanson, T.A., Moore, M.W., Shelton, D.L., Zioncheck, K.A., Rosenthal, A., Taga, T., Paoni, N.F., Wood, W.I. J. Biol. Chem. (1995)