Disease relevance of Human Rights

• In this study, we introduce a novel concept of map, based on the analysis of the wave morphology, which gives a direct evidence in the human right atrium on the spatiotemporal distribution of fibrillatory wave complexity in paroxysmal (PAF) and chronic (CAF) atrial fibrillation [1].
• Quantitative analysis of collagens and fibronectin expression in human right ventricular hypertrophy [2].
• METHODS: Isolated human right atrial trabeculae were subjected to 90-minute hypoxia and 120-minute reoxygenation in vitro, followed by adding 10(-4) M norepinephrine [3].
• The AIDS Law Project, the recipient of the 2nd Annual International Award for Action on HIV/AIDS and Human Rights, has been at the forefront of the struggle for human rights for people living with HIV/AIDS in South Africa. It has played a major role in convincing the South African government to implement a national HIV treatment plan [4].

Psychiatry related information on Human Rights

• This paper reports extended structured interviews with 35 survivors, including three doctors, carried out a year later on behalf of Human Right Watch. The literature on the likeliest CW agent, 3-quinuclidinyl benzilate (BZ), and on stress as a cause of hallucinations, is reviewed [5].
• In this paper three priority areas for action in the Eastern Mediterranean Region are suggested, namely: human rights, mental hospitals and community care, drug abuse, and reconstruction of the health care system in Afghanistan [6].
• Response to "Determinants of Decision Making for Circumcision" by C. Cielsielski-Carlucci, N. Milliken, and N.H. Cohen (CQ, Vol 5, No 2).Circumcision: ethical and human rights impact assessment [7].
• Nevertheless, dilemmas such as human rights versus political control, community integration versus community control, diversity versus centrality, huge demand but inadequate services seemed to challenge the further development of the mental health service in the PRC [8].

High impact information on Human Rights

• Health and human rights in El Salvador [9].
• In human right atria obtained from 21 patients during open-heart surgery, beta-adrenoceptor density [assessed by iodine-125-labeled (-)-cyanopindolol binding] and responsiveness (positive inotropic responses to isoprenaline) were linearly related to the beta-adrenoceptor density in the corresponding circulating lymphocytes [10].
• The AIDS litigation project. A national review of court and human rights commission decisions, Part II: Discrimination [11].
• To elucidate the synthesis of atrial natriuretic polypeptide (ANP) in the failing heart, 20 human right auricles obtained at cardiovascular surgery were studied [12].
• Marked regional differences of UEA-I binding in the nonneoplastic mucosae indicated that the constituents of glycoprotein with UEA-I binding sites in goblet cell mucus differed significantly between the human right and left large bowels [13].

Chemical compound and disease context of Human Rights

• Electrophysiological heterogeneity of atrial fibrillation and local effect of propafenone in the human right atrium: analysis based on symbolic dynamics [14].

Biological context of Human Rights

• Putative susceptibility markers of coronary artery disease: association between VDR genotype, smoking, and aromatic DNA adduct levels in human right atrial tissue [15].
• Through stimulation of Galphaq-coupled UT receptors, UII mediates contraction of vascular smooth muscle and endothelial-dependent vasorelaxation, and positive inotropy in human right atrium and ventricle [16].
• Angiotensin receptor type 1 mRNA in human right ventricular endomyocardial biopsies: downregulation in heart failure [17].
• The effects of 5-hydroxytryptamine (5-HT) on force of contraction (FC), action potential (AP) and calcium current (ICa) were studied in human right atrial and left ventricular heart muscle [18].
• We conclude that in human right atrium, ETA receptors couple to two different signal-transduction pathways: IP formation and inhibition of adenylate cyclase [19].

Anatomical context of Human Rights

• Positive inotropic responses were established to (-)-isoprenaline, RO363 (beta 1-selective), procaterol (beta 2-selective) and dopexamine in the absence or presence of the antagonist CGP 20712A (beta 1-selective) or ICI 118,551 (beta 2-selective) in electrically driven human right atrial appendage strips [20].
• Two new endothelin receptor radioligands, [125I]-BQ3020 and [125I]-[Ala1,3,11,15]ET-1, were characterized in tissue sections of human right atrium and left ventricle [21].
• Ketamine preconditions isolated human right atrial myocardium: roles of adenosine triphosphate-sensitive potassium channels and adrenoceptors [22].
• 1 In segments of human right atrial appendages and pulmonary arteries preincubated with [3H]-noradrenaline and superfused with physiological salt solution containing desipramine and corticosterone, the involvement of imidazoline receptors in the modulation of [3H]-noradrenaline release was investigated [23].
• The KOH method was also used to isolate intact, rod-shaped myocytes from formalin-fixed human cadaver left ventricles (control, n = 3; heart failure, n = 3) and from human right ventricle biopsy specimens (n = 6) [24].

Associations of Human Rights with chemical compounds

• We developed methods for identifying beta-adrenergic receptors in human right ventricular endomyocardial biopsy tissue with the radioligand (-)[125I]iodocyanopindolol (ICYP) [25].
• RESULTS: Carvedilol was a 13-fold more potent competitive antagonist of the effects of adrenaline at beta2-adrenoceptors (-logKB=10.13+/-0.08) than of noradrenaline at beta1-adrenoceptors (-logKB=9.02+/-0.07) in human right atrium [26].
• Angiotensin converting enzyme inhibition unmasks the sympathofacilitatory effect of bradykinin in human right atrium [27].
• In the human right atrium, cromakalim, and diazoxide did not affect significantly the release of [3H]NE [28].
• Histamine release from human right atrium [29].

Gene context of Human Rights

• 2. Highly specific RIAs were used to measure the levels of mature endothelin and big endothelin-1 immunoreactivity in extracts of human right ventricle [30].
• 6. In conclusion, the presynaptic alpha 2-autoreceptors in human right atrium are alpha 2C [31].
• We have now investigated in the isolated human right atrial appendage, a tissue whose beta-AR comprise around 2/3 of beta 1AR and 1/3 of beta 2AR, whether or not beta 2AR-mediated effects occur via activation of a cAMP pathway [32].
• Human liver and aorta predominantly expressed AT1-R mRNA, while human right atrium contained both AT1-R and AT2-R mRNAs [33].
• The aim of our study was to characterize functionally prejunctional neuropeptide Y (NPY) receptors in human and rabbit renal cortex, as well as in human right atrium [34].

Analytical, diagnostic and therapeutic context of Human Rights

• MATERIAL AND METHODS: In normal human right atrial tissues from five donors during cardiac transplantation, eNOS expression and localization were assessed by using Northern blot analysis, in situ hybridization, and immunohistochemical staining [35].
• In segments of human right atrial appendages preincubated with [3H]noradrenaline and superfused with physiological salt solution containing desipramine and corticosterone, we determined the effects of 5-hydroxytryptamine (5-HT) receptor agonists and antagonists on tritium overflow evoked by transmural electrical stimulation (2 Hz) [36].
• With this structural information and using reverse-transcriptase PCR technology we show that the ET2 gene is commonly expressed in human right atrial tissue [37].
• The effects of epinephrine on the electrophysiologic properties of human right atrail tissue, obtained at cardiac surgery, were evaluated utilizing standard microelectrode techniques [38].
• Fifty human right ventricular cast specimens were subjected to X-ray cineangiography in biplane right anterior oblique and left anterior oblique (RAO/LAO) projection [39].

References