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MeSH Review

Mandibular Condyle

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Disease relevance of Mandibular Condyle


High impact information on Mandibular Condyle


Biological context of Mandibular Condyle


Anatomical context of Mandibular Condyle

  • In conclusion, testosterone stimulates growth and local production of IGF-I and IGF-I-R in chondrocyte cell layers of an isolated organ culture of mice mandibular condyle [14].
  • The enhanced CTSB expression during the early stages of the enchondral ossification-like process in mandibular condyles in vitro suggests that CTSB participates in the degradation of cartilage matrix prior to the synthesis of bone matrix proteins [15].
  • In agreement with others, we believe that the only specific CT lesions of RA are erosions and cysts of the mandibular condyle, that there is no correlation between clinical and CT findings of TMJ in RA, and that the intensity of destructive lesions of TMJ on CT in RA is well correlated with the severity of the disease [16].
  • For example, compared to all other taxa, G. g. beringei has a significantly wider mandibular corpus and symphysis, larger area for the masseter muscle, higher mandibular ramus, and higher mandibular condyle relative to the occlusal plane of the mandible [17].
  • BACKGROUND: The objective of this study was to investigate the expression of matrilin-1 in arthritic articular cartilage of the mandibular condyle by means of immunohistochemical methods [18].

Associations of Mandibular Condyle with chemical compounds


Gene context of Mandibular Condyle


Analytical, diagnostic and therapeutic context of Mandibular Condyle


  1. Differential effects of hypothyroidism on the cartilage and the osteogenic process in the mandibular condyle: recovery by growth hormone and thyroxine. Lewinson, D., Bialik, G.M., Hochberg, Z. Endocrinology (1994) [Pubmed]
  2. Expression of matrix metalloproteinase-2 in osteoarthritic fibrocartilage from human mandibular condyle. Tanaka, A., Kawashiri, S., Kumagai, S., Takatsuka, S., Narinobou, M., Nakagawa, K., Tanaka, S. J. Oral Pathol. Med. (2000) [Pubmed]
  3. Osteochondroma of the mandibular condyle. Report of a case and review of the Japanese literature. Mizuno, A., Nakamura, T., Motegi, K., Shirasawa, H. International journal of oral surgery. (1983) [Pubmed]
  4. Gene expression during osteogenic differentiation in mandibular condyles in vitro. Strauss, P.G., Closs, E.I., Schmidt, J., Erfle, V. J. Cell Biol. (1990) [Pubmed]
  5. c-fos expression precedes osteogenic differentiation of cartilage cells in vitro. Closs, E.I., Murray, A.B., Schmidt, J., Schön, A., Erfle, V., Strauss, P.G. J. Cell Biol. (1990) [Pubmed]
  6. Leptin acts as a growth factor on the chondrocytes of skeletal growth centers. Maor, G., Rochwerger, M., Segev, Y., Phillip, M. J. Bone Miner. Res. (2002) [Pubmed]
  7. The insulin-sensitive glucose transporter (GLUT4) is involved in early bone growth in control and diabetic mice, but is regulated through the insulin-like growth factor I receptor. Maor, G., Karnieli, E. Endocrinology (1999) [Pubmed]
  8. Runx2 regulates endochondral ossification in condyle during mandibular advancement. Tang, G.H., Rabie, A.B. J. Dent. Res. (2005) [Pubmed]
  9. STT3, a novel essential gene related to the PKC1/STT1 protein kinase pathway, is involved in protein glycosylation in yeast. Yoshida, S., Ohya, Y., Nakano, A., Anraku, Y. Gene (1995) [Pubmed]
  10. In vivo effects of tunicamycin on chondrocytes of rat mandibular condyles as revealed by lectin cytochemistry. Yokose, S., Tajima, Y. Cell Tissue Res. (1992) [Pubmed]
  11. The early postnatal development of the murine mandibular condyle is regulated by endogenous insulin-like growth factor-I. Maor, G., Laron, Z., Eshet, R., Silbermann, M. J. Endocrinol. (1993) [Pubmed]
  12. Localization and inhibitory effect of basic fibroblast growth factor on chondrogenesis in cultured mouse mandibular condyle. Ogawa, T., Shimokawa, H., Fukada, K., Suzuki, S., Shibata, S., Ohya, K., Kuroda, T. J. Bone Miner. Metab. (2003) [Pubmed]
  13. Quantitative analysis of extracellular matrix proteins in hypertrophic layers of the mandibular condyle and temporal bone during human fetal development. Sato, I., Sunohara, M., Sato, T. Cells Tissues Organs (Print) (1999) [Pubmed]
  14. Testosterone stimulates insulin-like growth factor-I and insulin-like growth factor-I-receptor gene expression in the mandibular condyle--a model of endochondral ossification. Maor, G., Segev, Y., Phillip, M. Endocrinology (1999) [Pubmed]
  15. Isolation of a cathepsin B-encoding cDNA from murine osteogenic cells. Freimert, C., Closs, E.I., Silbermann, M., Erfle, V., Strauss, P.G. Gene (1991) [Pubmed]
  16. The temporomandibular joint in rheumatoid arthritis. Correlations between clinical and computed tomography features. Goupille, P., Fouquet, B., Cotty, P., Goga, D., Mateu, J., Valat, J.P. J. Rheumatol. (1990) [Pubmed]
  17. Masticatory form and function in the African apes. Taylor, A.B. Am. J. Phys. Anthropol. (2002) [Pubmed]
  18. Immunohistochemical study of matrilin-1 in arthritic articular cartilage of the mandibular condyle. Ohno, S., Murakami, K., Tanimoto, K., Sugiyama, H., Makihira, S., Shibata, T., Yoneno, K., Kato, Y., Tanne, K. J. Oral Pathol. Med. (2003) [Pubmed]
  19. Changes of cancellous bone mass in rat mandibular condyle following ovariectomy. Tanaka, M., Ejiri, S., Nakajima, M., Kohno, S., Ozawa, H. Bone (1999) [Pubmed]
  20. Region-specific bone mass changes in rat mandibular condyle following ovariectomy. Tanaka, M., Ejiri, S., Kohno, S., Ozawa, H. J. Dent. Res. (2000) [Pubmed]
  21. Mandibular growth and histologic changes in condylar cartilage of rats intoxicated with vitamin D3 or 1,25(OH)2D3 and pair-fed (undernourished) rats. Weinreb, M., Gazit, E., Weinreb, M.M. J. Dent. Res. (1986) [Pubmed]
  22. Proteoglycan expression in the rat temporomandibular joint in response to unilateral bite raise. Mao, J.J., Rahemtulla, F., Scott, P.G. J. Dent. Res. (1998) [Pubmed]
  23. Growth and differentiation of murine cartilage cells in vitro following a short-term exposure to triamcinolone acetonide. Weiss, A., Livne, E., Silbermann, M. Cell Tissue Res. (1990) [Pubmed]
  24. Msx1 is a regulator of bone formation during development and postnatal growth: in vivo investigations in a transgenic mouse model. Orestes-Cardoso, S., Nefussi, J.R., Lezot, F., Oboeuf, M., Pereira, M., Mesbah, M., Robert, B., Berdal, A. Connect. Tissue Res. (2002) [Pubmed]
  25. Biomineralization and adaptive plasticity of the temporomandibular joint in myostatin knockout mice. Nicholson, E.K., Stock, S.R., Hamrick, M.W., Ravosa, M.J. Arch. Oral Biol. (2006) [Pubmed]
  26. Expression of Notch1 and Math1 in mandibular condyle cartilage in neonatal mice. Shimizu, T., Tsujigiwa, H., Nagatsuka, H., Okafuji, N., Kurihara, S., Nagai, N., Kawakami, T. The Angle orthodontist. (2005) [Pubmed]
  27. Matrix formation in craniofacial cartilages of the rat. [35S]-sulfate incorporation studies. Størksen, K., Aukland, S., Kvinnsland, S. Acta Odontol. Scand. (1979) [Pubmed]
  28. Histologic changes in rat masticatory muscles subsequent to experimental increase of the occlusal vertical dimension. Akagawa, Y., Nikai, H., Tsuru, H. The Journal of prosthetic dentistry. (1983) [Pubmed]
  29. Changes in parathyroid hormone-related protein and 3-dimensional trabecular bone structure of the mandibular condyle following mandibular distraction osteogenesis in growing rats. Shibazaki, R., Maki, K., Tachikawa, T., Shibasaki, Y., Hinton, R.J., Carlson, D.S., Opperman, L.A. J. Oral Maxillofac. Surg. (2005) [Pubmed]
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