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Chemical Compound Review

NSC-6354     2-(4,5-dichloro-6-hydroxy-3- oxo-xanthen-9...

Synonyms: AG-K-07824, NSC6354, AC1L5AES, CTK5E9173, 81-87-8
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Disease relevance of Dichlorofluorescein


High impact information on Dichlorofluorescein


Chemical compound and disease context of Dichlorofluorescein


Biological context of Dichlorofluorescein


Anatomical context of Dichlorofluorescein


Associations of Dichlorofluorescein with other chemical compounds


Gene context of Dichlorofluorescein


Analytical, diagnostic and therapeutic context of Dichlorofluorescein


  1. Early midzonal oxidative stress preceding cell death in hypoperfused rat liver. Suematsu, M., Suzuki, H., Ishii, H., Kato, S., Yanagisawa, T., Asako, H., Suzuki, M., Tsuchiya, M. Gastroenterology (1992) [Pubmed]
  2. Ischemia-induced neutrophil activation and diapedesis is lipoxygenase dependent. Goldman, G., Welbourn, R., Paterson, I.S., Klausner, J.M., Kobzik, L., Valeri, C.R., Shepro, D., Hechtman, H.B. Surgery (1990) [Pubmed]
  3. Chloroform and carbon tetrachloride induce intrachromosomal recombination and oxidative free radicals in Saccharomyces cerevisiae. Brennan, R.J., Schiestl, R.H. Mutat. Res. (1998) [Pubmed]
  4. Leukocytes mediate acid aspiration-induced multiorgan edema. Goldman, G., Welbourn, R., Klausner, J.M., Kobzik, L., Valeri, C.R., Shepro, D., Hechtman, H.B. Surgery (1993) [Pubmed]
  5. Therapeutic effect of granulocyte colony-stimulating factor (G-CSF) on the protection against Listeria infection in SCID mice. Kayashima, S., Tsuru, S., Hata, N., Rokutanda, M. Immunology (1993) [Pubmed]
  6. CD18/ICAM-1-dependent oxidative NF-kappaB activation leading to nitric oxide production in rat Kupffer cells cocultured with syngeneic hepatoma cells. Kurose, I., Saito, H., Miura, S., Ebinuma, H., Higuchi, H., Watanabe, N., Zeki, S., Nakamura, T., Takaishi, M., Ishii, H. J. Clin. Invest. (1997) [Pubmed]
  7. Prostaglandin E1 abrogates early reductive stress and zone-specific paradoxical oxidative injury in hypoperfused rat liver. Suzuki, H., Suematsu, M., Ishii, H., Kato, S., Miki, H., Mori, M., Ishimura, Y., Nishino, T., Tsuchiya, M. J. Clin. Invest. (1994) [Pubmed]
  8. Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM-1 adherence. Entman, M.L., Youker, K., Shoji, T., Kukielka, G., Shappell, S.B., Taylor, A.A., Smith, C.W. J. Clin. Invest. (1992) [Pubmed]
  9. Nitric oxide inhibits H2O2-induced transferrin receptor-dependent apoptosis in endothelial cells: Role of ubiquitin-proteasome pathway. Kotamraju, S., Tampo, Y., Keszler, A., Chitambar, C.R., Joseph, J., Haas, A.L., Kalyanaraman, B. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  10. Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes. Duranteau, J., Chandel, N.S., Kulisz, A., Shao, Z., Schumacker, P.T. J. Biol. Chem. (1998) [Pubmed]
  11. Hypoxic constriction and reactive oxygen species in porcine distal pulmonary arteries. Liu, J.Q., Sham, J.S., Shimoda, L.A., Kuppusamy, P., Sylvester, J.T. Am. J. Physiol. Lung Cell Mol. Physiol. (2003) [Pubmed]
  12. A search for cellular and molecular mechanisms involved in depleted uranium (DU) toxicity. Pourahmad, J., Ghashang, M., Ettehadi, H.A., Ghalandari, R. Environ. Toxicol. (2006) [Pubmed]
  13. Role of mitochondrial oxidant generation in endothelial cell responses to hypoxia. Pearlstein, D.P., Ali, M.H., Mungai, P.T., Hynes, K.L., Gewertz, B.L., Schumacker, P.T. Arterioscler. Thromb. Vasc. Biol. (2002) [Pubmed]
  14. Endothelial cell proliferation associated with abrupt reduction in shear stress is dependent on reactive oxygen species. Milovanova, T., Manevich, Y., Haddad, A., Chatterjee, S., Moore, J.S., Fisher, A.B. Antioxid. Redox Signal. (2004) [Pubmed]
  15. beta-Amyloid toxicity in organotypic hippocampal cultures: protection by EUK-8, a synthetic catalytic free radical scavenger. Bruce, A.J., Malfroy, B., Baudry, M. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  16. Polymorphonuclear leukocyte dysregulation during the systemic inflammatory response syndrome. Simms, H.H., D'Amico, R. Blood (1994) [Pubmed]
  17. Induction of expression of genes encoding components of the respiratory burst oxidase during differentiation of human myeloid cell lines induced by tumor necrosis factor and gamma-interferon. Gupta, J.W., Kubin, M., Hartman, L., Cassatella, M., Trinchieri, G. Cancer Res. (1992) [Pubmed]
  18. Cytoprotective effects of hyaluronic acid and Carbomer 934P in ocular surface epithelial cells. Debbasch, C., De La Salle, S.B., Brignole, F., Rat, P., Warnet, J.M., Baudouin, C. Invest. Ophthalmol. Vis. Sci. (2002) [Pubmed]
  19. In high glucose protein kinase C-zeta activation is required for mesangial cell generation of reactive oxygen species. Kwan, J., Wang, H., Munk, S., Xia, L., Goldberg, H.J., Whiteside, C.I. Kidney Int. (2005) [Pubmed]
  20. Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats. Walter, P.B., Knutson, M.D., Paler-Martinez, A., Lee, S., Xu, Y., Viteri, F.E., Ames, B.N. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  21. Involvement of nitric oxide in target-cell lysis and DNA fragmentation induced by murine natural killer cells. Filep, J.G., Baron, C., Lachance, S., Perreault, C., Chan, J.S. Blood (1996) [Pubmed]
  22. Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+. Al-Mehdi, A.B., Zhao, G., Dodia, C., Tozawa, K., Costa, K., Muzykantov, V., Ross, C., Blecha, F., Dinauer, M., Fisher, A.B. Circ. Res. (1998) [Pubmed]
  23. Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition. Yerushalmi, B., Dahl, R., Devereaux, M.W., Gumpricht, E., Sokol, R.J. Hepatology (2001) [Pubmed]
  24. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione. García-Ruiz, C., Colell, A., Marí, M., Morales, A., Fernández-Checa, J.C. J. Biol. Chem. (1997) [Pubmed]
  25. Daunorubicin-induced apoptosis in rat cardiac myocytes is inhibited by dexrazoxane. Sawyer, D.B., Fukazawa, R., Arstall, M.A., Kelly, R.A. Circ. Res. (1999) [Pubmed]
  26. Expression of heme oxygenase in arsenic-resistant human lung adenocarcinoma cells. Lee, T.C., Ho, I.C. Cancer Res. (1994) [Pubmed]
  27. Proinflammatory cytokines, markers of cardiovascular risks, oxidative stress, and lipid peroxidation in patients with hyperglycemic crises. Stentz, F.B., Umpierrez, G.E., Cuervo, R., Kitabchi, A.E. Diabetes (2004) [Pubmed]
  28. Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes. El-Remessy, A.B., Al-Shabrawey, M., Khalifa, Y., Tsai, N.T., Caldwell, R.B., Liou, G.I. Am. J. Pathol. (2006) [Pubmed]
  29. Doxorubicin-induced apoptosis is associated with increased transcription of endothelial nitric-oxide synthase. Effect of antiapoptotic antioxidants and calcium. Kalivendi, S.V., Kotamraju, S., Zhao, H., Joseph, J., Kalyanaraman, B. J. Biol. Chem. (2001) [Pubmed]
  30. Reactive oxygen species as downstream mediators of angiogenic signaling by vascular endothelial growth factor receptor-2/KDR. Colavitti, R., Pani, G., Bedogni, B., Anzevino, R., Borrello, S., Waltenberger, J., Galeotti, T. J. Biol. Chem. (2002) [Pubmed]
  31. Increased formation of reactive oxygen species, but no changes in glutathione peroxidase activity, in striata of mice transgenic for the Huntington's disease mutation. Pérez-Severiano, F., Santamaría, A., Pedraza-Chaverri, J., Medina-Campos, O.N., Ríos, C., Segovia, J. Neurochem. Res. (2004) [Pubmed]
  32. Resveratrol reduces oxidation and proliferation of human retinal pigment epithelial cells via extracellular signal-regulated kinase inhibition. King, R.E., Kent, K.D., Bomser, J.A. Chem. Biol. Interact. (2005) [Pubmed]
  33. Hypoxia/reoxygenation stimulates Ca2+-dependent ICAM-1 mRNA expression in human aortic endothelial cells. Ziegelstein, R.C., He, C., Hu, Q. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
  34. Alpha-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes is mediated via thioredoxin-1-sensitive oxidative modification of thiols on Ras. Kuster, G.M., Pimentel, D.R., Adachi, T., Ido, Y., Brenner, D.A., Cohen, R.A., Liao, R., Siwik, D.A., Colucci, W.S. Circulation (2005) [Pubmed]
  35. Mesangial cell NADPH oxidase upregulation in high glucose is protein kinase C dependent and required for collagen IV expression. Xia, L., Wang, H., Goldberg, H.J., Munk, S., Fantus, I.G., Whiteside, C.I. Am. J. Physiol. Renal Physiol. (2006) [Pubmed]
  36. Enhancement of reperfusion injury by elevation of microvascular pressures. Takase, S., Lerond, L., Bergan, J.J., Schmid-Schönbein, G.W. Am. J. Physiol. Heart Circ. Physiol. (2002) [Pubmed]
  37. Fluorescence microtopography of oxidative stress in lung ischemia-reperfusion. al-Mehdi, A., Shuman, H., Fisher, A.B. Lab. Invest. (1994) [Pubmed]
  38. Signaling pathway for nitric oxide generation with simulated ischemia in flow-adapted endothelial cells. Wei, Z., Al-Mehdi, A.B., Fisher, A.B. Am. J. Physiol. Heart Circ. Physiol. (2001) [Pubmed]
  39. Rehydration of the lichen Ramalina lacera results in production of reactive oxygen species and nitric oxide and a decrease in antioxidants. Weissman, L., Garty, J., Hochman, A. Appl. Environ. Microbiol. (2005) [Pubmed]
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