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Chemical Compound Review

sodium hypochlorite     sodium hypochlorite

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Disease relevance of sodium hypochlorite


Psychiatry related information on sodium hypochlorite

  • Early psychiatry at Yale: Milton C. Winternitz and the founding of the Department of Psychiatry and Mental Hygiene [6].
  • The Learning-Orientation Grade-Orientation Scale of Eison, Pollio, and Milton was administered to 85 college students and analyzed to study the psychometric properties of the instrument [7].
  • Open University Press, Milton Keynes) and Locus of Control model (LC; Psychological Monographs, (1966) (80) in understanding the intention to use bicycle helmet use among bicycle helmet owners [8].
  • Seeds of strategic and interactional psychotherapies: seminal contributions of Milton H. Erickson [9].
  • Traditional psychoanalytic theories of infancy were challenged a number of years ago by Peterfreund (1978) and Milton Klein (1980), but published debate on this issue has only recently begun to appear [10].

High impact information on sodium hypochlorite


Chemical compound and disease context of sodium hypochlorite


Biological context of sodium hypochlorite


Anatomical context of sodium hypochlorite

  • In this issue Glater et al. demonstrate a new type of linkage through the adapter protein, milton, and the mitochondrial membrane GTPase, miro [22].
  • Milton controls the early acquisition of mitochondria by Drosophila oocytes [23].
  • METHODS: An anti-AP-1 decoy oligodeoxynucleotide (dODN) strategy was devised in which the dODN-containing solution (20 nmol) was administered locally through a Dispatch catheter into the coronary arteries of hypercholesterolemic minipigs at the time of PTCA (AVE-GFX stent) [24].
  • CONCLUSION: Efficient arterial gene delivery to endothelial and superficial smooth muscle cells is feasible using local delivery of adenoviral vectors via the Dispatch autoperfusion catheter, in both normal and atheromatous arteries [25].
  • The mechanism responsible for sodium-hypochlorite-induced reduction in dentin bond strength and its reversal with reducing agents is unknown [26].

Associations of sodium hypochlorite with other chemical compounds


Gene context of sodium hypochlorite

  • Milton shares approximately 44% amino acid homology with GRIF-1 [31].
  • We have evaluated a global screening test for the protein C pathway, the 'ProC Global' (Dade Behring Ltd, Milton Keynes, UK) [32].
  • METHODS: PDE5 was isolated from the human platelet and PDE4 from the rat liver tissue using the FPLC system (Pharmacia, Milton Keynes, UK) and the Mono Q column [33].
  • Two weeks later, the patency of the stented arteries was documented by coronary angiography, and the hRAD50 construct or empty vector mixed with lipid was delivered to one of the stented arteries in each pig using a Dispatch catheter [34].
  • Objective: This retrospective study evaluated the appropriateness of requests assigned the alpha determinant at the time of dispatch by Emergency Medical Dispatchers using the Medical Priority Dispatch System (MPDS) [35].

Analytical, diagnostic and therapeutic context of sodium hypochlorite

  • In vivo studies demonstrated immediate deposition of 0.12% of the urokinase delivered by the Dispatch catheter to the angioplasty site, compared with 0.0007% with systemic bolus, 0.003% with guiding catheter infusion, and 0.007% with local infusion with an end-hole catheter (P < .001) [1].
  • Using a database of 30 ganzfeld and autoganzfeld studies, Milton and Wiseman's meta-analysis yielded an effect size (ES) of only 0.013 (Stouffer Z = 0.70, p = .24, one-tailed) [36].
  • A retrospective study of 29 patients with invasive carcinoma of the vagina was completed at The Milton S [37].
  • Twenty-seven patients with 76 pressure sores received treatment with hydrocolloid dressings (HCDs) and 25 patients with 52 pressure sores received treatment with Dakin's solution (chloramine-T)-soaked wet-to-dry dressings [38].
  • We have investigated the use of sodium hypochloride (Clorox), in comparison to concentrated HCl, for PCR sterilization [39].


  1. Enhanced intracoronary thrombolysis with urokinase using a novel, local drug delivery system. In vitro, in vivo, and clinical studies. Mitchel, J.F., Fram, D.B., Palme, D.F., Foster, R., Hirst, J.A., Azrin, M.A., Bow, L.M., Eldin, A.M., Waters, D.D., McKay, R.G. Circulation (1995) [Pubmed]
  2. Corynebacterium parvum versus bacille Calmette-Guérin adjuvant immunotherapy of stage II malignant melanoma. Lipton, A., Harvey, H.A., Balch, C.M., Antle, C.E., Heckard, R., Bartolucci, A.A. J. Clin. Oncol. (1991) [Pubmed]
  3. Myasthenia gravis and myotonic dystrophy in a 13-year-old girl. G. Milton Shy Award Essay, 1976. Schoen, R.T. Neurology (1977) [Pubmed]
  4. Wound isolate of Salmonella typhimurium that became chlorate resistant after exposure to Dakin's solution: concomitant loss of hydrogen sulfide production, gas production, and nitrate reduction. Lannigan, R., Hussain, Z. J. Clin. Microbiol. (1993) [Pubmed]
  5. Intravascular adenovirus-mediated lipoprotein-associated phospholipase A2 gene transfer reduces neointima formation in balloon-denuded rabbit aorta. Turunen, P., Puhakka, H., Rutanen, J., Hiltunen, M.O., Heikura, T., Gruchala, M., Ylä-Herttuala, S. Atherosclerosis (2005) [Pubmed]
  6. Early psychiatry at Yale: Milton C. Winternitz and the founding of the Department of Psychiatry and Mental Hygiene. Engel, J.W. The Yale journal of biology and medicine. (1994) [Pubmed]
  7. Psychometric properties of the Learning-Orientation Grade-Orientation II Scale. Jacobs, K.W. Perceptual and motor skills. (1992) [Pubmed]
  8. Can social psychological models be used to promote bicycle helmet use among teenagers? A comparison of the Health Belief Model, Theory of Planned Behavior and the Locus of Control. Lajunen, T., Räsänen, M. Journal of safety research. (2004) [Pubmed]
  9. Seeds of strategic and interactional psychotherapies: seminal contributions of Milton H. Erickson. Zeig, J.K., Geary, B.B. The American journal of clinical hypnosis. (1990) [Pubmed]
  10. Psychoanalytic theories of infant differentiation of self and other. Gillett, E. The Journal of the American Academy of Psychoanalysis. (1994) [Pubmed]
  11. Axonal transport of mitochondria to synapses depends on milton, a novel Drosophila protein. Stowers, R.S., Megeath, L.J., Górska-Andrzejak, J., Meinertzhagen, I.A., Schwarz, T.L. Neuron (2002) [Pubmed]
  12. Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent. Glater, E.E., Megeath, L.J., Stowers, R.S., Schwarz, T.L. J. Cell Biol. (2006) [Pubmed]
  13. Effect of low molecular weight heparin (fragmin) on bleeding after cardiac surgery. Clark, S.C., Vitale, N., Zacharias, J., Forty, J. Ann. Thorac. Surg. (2000) [Pubmed]
  14. Therapeutic rounds at the Milton S. Hershey Medical Center: central nervous system toxicity caused by lidocaine. Schneck, D.W. Clinical therapeutics. (1983) [Pubmed]
  15. Permeabilization of eggs of the malaria mosquito Anopheles gambiae. Valencia, M.D., Miller, L.H., Mazur, P. Cryobiology (1996) [Pubmed]
  16. Culturing the throat to protect the heart: Dr. Milton Markowitz and the prevention of rheumatic fever. Murray, T., Grey, M. Connecticut medicine. (2000) [Pubmed]
  17. A toxicity index of skin and wound cleansers used on in vitro fibroblasts and keratinocytes. Wilson, J.R., Mills, J.G., Prather, I.D., Dimitrijevich, S.D. Advances in skin & wound care. (2005) [Pubmed]
  18. Bacterial spores survive treatment with commercial sterilants and disinfectants. Sagripanti, J.L., Bonifacino, A. Appl. Environ. Microbiol. (1999) [Pubmed]
  19. The mentor effect in student evaluation. Coulson, C.C., Kunselman, A.R., Cain, J., Legro, R.S. Obstetrics and gynecology. (2000) [Pubmed]
  20. Prediction of the excessive perioperative bleeding in patients undergoing coronary artery bypass grafting: role of aspirin and platelet glycoprotein IIIa polymorphism. Morawski, W., Sanak, M., Cisowski, M., Szczeklik, M., Szczeklik, W., Dropinski, J., Waclawczyk, T., Ulczok, R., Bochenek, A. J. Thorac. Cardiovasc. Surg. (2005) [Pubmed]
  21. Stent implantation in patient with visible intracoronary thrombus and compromised left ventricular function, after local thrombolysis using the Dispatch catheter. Antonellis, I.P., Patsilinakos, S.P., Pamboukas, C.A., Kranidis, A.J., Margaris, N.G., Kostopoulos, C., Tavernarakis, A.G., Rokas, S.G. International journal of cardiology. (1998) [Pubmed]
  22. Paradigm lost: milton connects kinesin heavy chain to miro on mitochondria. Rice, S.E., Gelfand, V.I. J. Cell Biol. (2006) [Pubmed]
  23. Milton controls the early acquisition of mitochondria by Drosophila oocytes. Cox, R.T., Spradling, A.C. Development (2006) [Pubmed]
  24. Decoy oligodeoxynucleotide against activator protein-1 reduces neointimal proliferation after coronary angioplasty in hypercholesterolemic minipigs. Buchwald, A.B., Wagner, A.H., Webel, C., Hecker, M. J. Am. Coll. Cardiol. (2002) [Pubmed]
  25. The Dispatch catheter as a delivery tool for arterial gene transfer. Tahlil, O., Brami, M., Feldman, L.J., Branellec, D., Steg, P.G. Cardiovasc. Res. (1997) [Pubmed]
  26. A nanoleakage perspective on bonding to oxidized dentin. Yiu, C.K., García-Godoy, F., Tay, F.R., Pashley, D.H., Imazato, S., King, N.M., Lai, S.C. J. Dent. Res. (2002) [Pubmed]
  27. Calcium oxalate crystals in the thyroid. Their identification, prevalence, origin, and possible significance. Reid, J.D., Choi, C.H., Oldroyd, N.O. Am. J. Clin. Pathol. (1987) [Pubmed]
  28. Effects of sodium hypochlorite (Dakin's solution) on cells of the wound module. Kozol, R.A., Gillies, C., Elgebaly, S.A. Archives of surgery (Chicago, Ill. : 1960) (1988) [Pubmed]
  29. Effect of local delivery of L-arginine on in-stent restenosis in humans. Suzuki, T., Hayase, M., Hibi, K., Hosokawa, H., Yokoya, K., Fitzgerald, P.J., Yock, P.G., Cooke, J.P., Suzuki, T., Yeung, A.C. Am. J. Cardiol. (2002) [Pubmed]
  30. Synthesis, chromatographic resolution and chiroptical properties of carboxyibuprofen stereoisomers: major metabolites of ibuprofen in man. Tan, S.C., Baker, J.A., Stevens, N., deBiasi, V., Salter, C., Chalaux, M., Afarinkia, K., Hutt, A.J. Chirality. (1997) [Pubmed]
  31. GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin. Brickley, K., Smith, M.J., Beck, M., Stephenson, F.A. J. Biol. Chem. (2005) [Pubmed]
  32. Evaluation of a global screening assay for the investigation of the protein C anticoagulant pathway. Rimmer, J.E., Cooper, P.C., Brookfield, C.J., Preston, F.E., Makris, M. Clinical and laboratory haematology. (2000) [Pubmed]
  33. Effects of icariin on cGMP-specific PDE5 and cAMP-specific PDE4 activities. Xin, Z.C., Kim, E.K., Lin, C.S., Liu, W.J., Tian, L., Yuan, Y.M., Fu, J. Asian J. Androl. (2003) [Pubmed]
  34. Local RAD50 gene delivery induces regression of preformed porcine coronary in-stent neointimal hyperplasia. Ahn, Y.K., Kook, H., Jeong, M.H., Ahn, K.Y., Cho, J.G., Park, J.C., Kang, J.C., Kim, K.K. The journal of gene medicine. (2004) [Pubmed]
  35. Low Acuity EMS Dispatch Criteria Can Reliably Identify Patients without High-Acuity Illness or Injury. Hinchey, P., Myers, B., Zalkin, J., Lewis, R., Garner, D. Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors (2007) [Pubmed]
  36. Does psi exist? Comments on Milton and Wiseman's (1999) meta-analysis of ganzfeld research. Storm, L., Ertel, S. Psychological bulletin. (2001) [Pubmed]
  37. Primary invasive carcinoma of the vagina. Manetta, A., Pinto, J.L., Larson, J.E., Stevens, C.W., Pinto, J.S., Podczaski, E.S. Obstetrics and gynecology. (1988) [Pubmed]
  38. Improved pressure sore healing with hydrocolloid dressings. Gorse, G.J., Messner, R.L. Archives of dermatology. (1987) [Pubmed]
  39. PCR: how to kill unwanted DNA. Prince, A.M., Andrus, L. BioTechniques (1992) [Pubmed]
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