Chemical Compound Review:
Barbiturate 1,3-diazinane-2,4,6-trione
Synonyms:
Malonylurea, Malonyluree, Barbitursaeure, AC1MMJIY, SureCN38707, ...
- Electrophysiological and metabolic effects of a convulsant barbiturate on dissociated mouse primary sensory neurons. Pearce, R.J., Duchen, M.R. J. Physiol. (Lond.) (1995)
- Thiopental-induced apoptosis in lymphocytes is independent of CD95 activation. Keel, M., Mica, L., Stover, J., Stocker, R., Trentz, O., Härter, L. Anesthesiology (2005)
- Depth of EEG suppression and outcome in barbiturate anesthetic treatment for refractory status epilepticus. Krishnamurthy, K.B., Drislane, F.W. Epilepsia (1999)
- Transcranial Doppler ultrasonography to confirm brain death: a meta-analysis. Monteiro, L.M., Bollen, C.W., van Huffelen, A.C., Ackerstaff, R.G., Jansen, N.J., van Vught, A.J. Intensive care medicine (2006)
- 5-(2-Cyclohexylideneethyl)-5-ethyl barbituric acid (CHEB): correlation of hypnotic and convulsant properties with alterations of synaptosomal 45Ca2+ influx. Chandler, L.J., Leslie, S.W., Gonzales, R. Eur. J. Pharmacol. (1986)
- Upper airway function during sleep and wakefulness: experimental studies on normal and anesthetized cats. Orem, J., Lydic, R. Sleep. (1978)
- Mechanism of barbituric-acid protection against inhibition by alloxan of glucose-induced insulin release. Weaver, D.C., McDaniel, M.L., Lacy, P.E. Diabetes (1978)
- The comparative effects of barbituric acid phenobarbital on blood glucose and insulin secretion in mice. Mennear, J.H., Schonwalder, C., Yau, E.T. Diabetologia (1976)
- Transformation of barbituric acid into alloxan by hydroxyl radicals: interaction with melatonin and with other hydroxyl radical scavengers. Brömme, H.J., Mörke, W., Peschke, E. J. Pineal Res. (2002)
- Structural basis for inhibition of Escherichia coli uridine phosphorylase by 5-substituted acyclouridines. Bu, W., Settembre, E.C., el Kouni, M.H., Ealick, S.E. Acta Crystallogr. D Biol. Crystallogr. (2005)
- Synthesis of pyrimidine derivatives possessing an antioxidative property and their inhibitory effects on picryl chloride-induced contact hypersensitivity reaction. Isobe, Y., Hirota, K. Chem. Pharm. Bull. (2003)
- Sarcolemmal and mitochondrial adenosine triphosphate- dependent potassium channels: mechanism of desflurane-induced cardioprotection. Toller, W.G., Gross, E.R., Kersten, J.R., Pagel, P.S., Gross, G.J., Warltier, D.C. Anesthesiology (2000)
- Multiple actions of convulsant barbiturates on mouse neurons in cell culture. Skerritt, J.H., Macdonald, R.L. J. Pharmacol. Exp. Ther. (1984)
- Palladium-catalyzed asymmetric allylic alkylation of barbituric acid derivatives: enantioselective syntheses of cyclopentobarbital and pentobarbital. Trost, B.M., Schroeder, G.M. J. Org. Chem. (2000)
- Differing actions of convulsant and nonconvulsant barbiturates: an electrophysiological study in the isolated spinal cord of the rat. Nicholson, G.M., Spence, I., Johnston, G.A. Neuropharmacology (1988)
- Cardioprotective effects of monophosphoryl lipid A, a novel endotoxin analogue, in the dog. Yao, Z., Auchampach, J.A., Pieper, G.M., Gross, G.J. Cardiovasc. Res. (1993)
- Strychnine-like action of the convulsant barbiturate, CHEB. Nicholson, G.M., Spence, I., Johnston, G.A. Neuropharmacology (1985)
- Inhibitory effects of barbiturates on nicotinic acetylcholine receptors in rat central nervous system neurons. Kamiya, Y., Andoh, T., Watanabe, I., Higashi, T., Itoh, H. Anesthesiology (2001)
- Effects of barbiturates with or without liver-tumor-promoting activity on survival and DNA synthesis of suckling and adult rat hepatocytes in serum-free primary culture. Miyazaki, M., Bai, L., Tsuboi, S., Namba, M. J. Cancer Res. Clin. Oncol. (1992)
- Brbiturate spindle activity in the association cortex of the cat and its relation to spindle activity in the somatosensory system. Ganes, T. Brain Res. (1976)
- Comparison of the effects of a convulsant barbiturate on the release of endogenous and radiolabeled amino acids from slices of mouse hippocampus. Holtman, J.R., Richter, J.A. J. Neurochem. (1983)
- Promotion by sodium barbital of renal cortical and transitional cell tumors, but not intestinal tumors, in F344 rats given methyl(acetoxymethyl)nitrosamine, and lack of effect of phenobarbital, amobarbital, or barbituric acid on development of either renal or intestinal tumors. Diwan, B.A., Ohshima, M., Rice, J.M. Carcinogenesis (1989)
- Crystallization of yeast orotidine 5'-monophosphate decarboxylase complexed with 1-(5'-phospho-beta-D-ribofuranosyl) barbituric acid. Bell, J.B., Jones, M.E., Carter, C.W. Proteins (1991)
- 5-Benzylbarbituric acid derivatives, potent and specific inhibitors of uridine phosphorylase. Naguib, F.N., Levesque, D.L., Wang, E.C., Panzica, R.P., el Kouni, M.H. Biochem. Pharmacol. (1993)
- Effects of anticonvulsants in vivo on high affinity choline uptake in vitro in mouse hippocampal synaptosomes. Miller, J.A., Richter, J.A. Br. J. Pharmacol. (1985)
- Pharmacology of aminoglutethimide: structure/activity relationships and receptor interactions. Nicholls, P.J., Daly, M.J., Smith, H.J. Breast Cancer Res. Treat. (1986)
- Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14. Blagg, J.A., Noe, M.C., Wolf-Gouveia, L.A., Reiter, L.A., Laird, E.R., Chang, S.P., Danley, D.E., Downs, J.T., Elliott, N.C., Eskra, J.D., Griffiths, R.J., Hardink, J.R., Haugeto, A.I., Jones, C.S., Liras, J.L., Lopresti-Morrow, L.L., Mitchell, P.G., Pandit, J., Robinson, R.P., Subramanyam, C., Vaughn-Bowser, M.L., Yocum, S.A. Bioorg. Med. Chem. Lett. (2005)
- Metabolic resistance to tight-binding inhibitors of enzymes involved in the de novo pyrimidine pathway. Simulation of time-dependent effects. Duggleby, R.G., Christopherson, R.I. Eur. J. Biochem. (1984)
- Isolation of drugs from post mortem specimens with the automated sample processor. Part I. Barbiturate derivatives. Balkon, J., Prendes, D., Viola, J. Journal of analytical toxicology. (1982)
- Catalymetric - thermometric titration of some derivatives of barbituric acid. Bark, L.S., Ladipo, O. The Analyst. (1976)
- Simple high-performance liquid chromatographic method to verify the direct barbituric acid assay for urinary cotinine. Ubbink, J.B., Lagendijk, J., Vermaak, W.H. J. Chromatogr. (1993)
- A barbiturate screening assay for the Abbott AxSYM analyzer. Adamczyk, M., Douglas, J., Grote, J., Harrington, C.A. Journal of analytical toxicology. (1998)
- The epoxide-diol pathway in the metabolism of vinylbital in rat and man. Vermeulen, N.P., Bakker, B.H., Eylers, D., Breimer, D.D. Xenobiotica (1980)