Gene Review:
Hoxa5 - homeobox A5
Mus musculus
Synonyms:
Homeobox protein Hox-1.3, Homeobox protein Hox-A5, Homeobox protein M2, Hox-1.3, Hoxa-5
- Hoxa5 overexpression correlates with IGFBP1 upregulation and postnatal dwarfism: evidence for an interaction between Hoxa5 and Forkhead box transcription factors. Foucher, I., Volovitch, M., Frain, M., Kim, J.J., Souberbielle, J.C., Gan, L., Unterman, T.G., Prochiantz, A., Trembleau, A. Development (2002)
- Perturbed thyroid morphology and transient hypothyroidism symptoms in Hoxa5 mutant mice. Meunier, D., Aubin, J., Jeannotte, L. Dev. Dyn. (2003)
- Respiratory adaptations to lung morphological defects in adult mice lacking Hoxa5 gene function. Kinkead, R., LeBlanc, M., Gulemetova, R., Lalancette-Hébert, M., Lemieux, M., Mandeville, I., Jeannotte, L. Pediatr. Res. (2004)
- Coding sequence and expression of the homeobox gene Hox 1.3. Fibi, M., Zink, B., Kessel, M., Colberg-Poley, A.M., Labeit, S., Lehrach, H., Gruss, P. Development (1988)
- Activation of Hox gene expression by Hoxa-5. Lobe, C.G. DNA Cell Biol. (1995)
- Impact of the loss of Hoxa5 function on lung alveogenesis. Mandeville, I., Aubin, J., LeBlanc, M., Lalancette-Hébert, M., Janelle, M.F., Tremblay, G.M., Jeannotte, L. Am. J. Pathol. (2006)
- A universal influenza A vaccine based on the extracellular domain of the M2 protein. Neirynck, S., Deroo, T., Saelens, X., Vanlandschoot, P., Jou, W.M., Fiers, W. Nat. Med. (1999)
- The mouse Hox-1.3 gene is functionally equivalent to the Drosophila Sex combs reduced gene. Zhao, J.J., Lazzarini, R.A., Pick, L. Genes Dev. (1993)
- Specification of axial identity in the mouse: role of the Hoxa-5 (Hox1.3) gene. Jeannotte, L., Lemieux, M., Charron, J., Poirier, F., Robertson, E.J. Genes Dev. (1993)
- The role of exon sequences in splice site selection. Watakabe, A., Tanaka, K., Shimura, Y. Genes Dev. (1993)
- Region-specific enhancers near two mammalian homeo box genes define adjacent rostrocaudal domains in the central nervous system. Tuggle, C.K., Zakany, J., Cianetti, L., Peschle, C., Nguyen-Huu, M.C. Genes Dev. (1990)
- Molecular cloning and characterization of the immunologically protective surface glycoprotein GP46/M-2 of Leishmania amazonensis. Lohman, K.L., Langer, P.J., McMahon-Pratt, D. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Isolation and genetic characterization of ethanol-resistant reovirus mutants. Wessner, D.R., Fields, B.N. J. Virol. (1993)
- Effect of cyclic AMP on the cell cycle regulation of ribonucleotide reductase M2 subunit messenger RNA concentrations in wild-type and mutant S49 T lymphoma cells. Albert, D.A., Nodzenski, E., Yim, G., Kowalski, J. J. Cell. Physiol. (1990)
- The cysteine residues of the M2 protein are not required for influenza A virus replication. Castrucci, M.R., Hughes, M., Calzoletti, L., Donatelli, I., Wells, K., Takada, A., Kawaoka, Y. Virology (1997)
- A "universal" human influenza A vaccine. Fiers, W., De Filette, M., Birkett, A., Neirynck, S., Min Jou, W. Virus Res. (2004)
- Cooperation of Hoxa5 and Pax1 genes during formation of the pectoral girdle. Aubin, J., Lemieux, M., Moreau, J., Lapointe, J., Jeannotte, L. Dev. Biol. (2002)
- Transcriptional interferences at the Hoxa4/Hoxa5 locus: importance of correct Hoxa5 expression for the proper specification of the axial skeleton. Aubin, J., Lemieux, M., Tremblay, M., Behringer, R.R., Jeannotte, L. Dev. Dyn. (1998)
- Hoxa5 gene regulation: A gradient of binding activity to a brachial spinal cord element. Nowling, T., Zhou, W., Krieger, K.E., Larochelle, C., Nguyen-Huu, M.C., Jeannotte, L., Tuggle, C.K. Dev. Biol. (1999)
- Transgenic mice ectopically expressing HOXA5 in the dorsal spinal cord show structural defects of the cervical spinal cord along with sensory and motor defects of the forelimb. Krieger, K.E., Abbott, M.A., Joksimovic, M., Lueth, P.A., Sonea, I.M., Jeannotte, L., Tuggle, C.K. Brain Res. Dev. Brain Res. (2004)
- Regulation of the Hoxa4 and Hoxa5 genes in the embryonic mouse lung by retinoic acid and TGFbeta1: implications for lung development and patterning. Packer, A.I., Mailutha, K.G., Ambrozewicz, L.A., Wolgemuth, D.J. Dev. Dyn. (2000)
- Molecular cloning and expression of the functional gene encoding the M2 subunit of mouse ribonucleotide reductase: a new dominant marker gene. Thelander, M., Thelander, L. EMBO J. (1989)
- Role of the mu 1 protein in reovirus stability and capacity to cause chromium release from host cells. Hooper, J.W., Fields, B.N. J. Virol. (1996)
- Human cytotoxic T-lymphocyte repertoire to influenza A viruses. Jameson, J., Cruz, J., Ennis, F.A. J. Virol. (1998)
- Mouse Hox-3.4: homeobox sequence and embryonic expression patterns compared with other members of the Hox gene network. Gaunt, S.J., Coletta, P.L., Pravtcheva, D., Sharpe, P.T. Development (1990)
- Stomach regional specification requires Hoxa5-driven mesenchymal-epithelial signaling. Aubin, J., Déry, U., Lemieux, M., Chailler, P., Jeannotte, L. Development (2002)
- Cdx protein interaction with Hoxa5 regulatory sequences contributes to Hoxa5 regional expression along the axial skeleton. Tabariès, S., Lapointe, J., Besch, T., Carter, M., Woollard, J., Tuggle, C.K., Jeannotte, L. Mol. Cell. Biol. (2005)
- The Hox-1.3 homeo box protein is a sequence-specific DNA-binding phosphoprotein. Odenwald, W.F., Garbern, J., Arnheiter, H., Tournier-Lasserve, E., Lazzarini, R.A. Genes Dev. (1989)
- Specific expression of the Hox 1.3 homeo box gene in murine embryonic structures originating from or induced by the mesoderm. Dony, C., Gruss, P. EMBO J. (1987)
- Influenza A vaccine based on the extracellular domain of M2: weak protection mediated via antibody-dependent NK cell activity. Jegerlehner, A., Schmitz, N., Storni, T., Bachmann, M.F. J. Immunol. (2004)