Gene Review:
Dusp1 - dual specificity phosphatase 1
Mus musculus
Synonyms:
3CH134, 3ch134, Dual specificity protein phosphatase 1, MAP kinase phosphatase 1, MKP-1, ...
- MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock. Zhao, Q., Wang, X., Nelin, L.D., Yao, Y., Matta, R., Manson, M.E., Baliga, R.S., Meng, X., Smith, C.V., Bauer, J.A., Chang, C.H., Liu, Y. J. Exp. Med. (2006)
- Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages. Chen, P., Li, J., Barnes, J., Kokkonen, G.C., Lee, J.C., Liu, Y. J. Immunol. (2002)
- Calcineurin enhances MAPK phosphatase-1 expression and p38 MAPK inactivation in cardiac myocytes. Lim, H.W., New, L., Han, J., Molkentin, J.D. J. Biol. Chem. (2001)
- Knockout of Mkp-1 enhances the host inflammatory responses to gram-positive bacteria. Wang, X., Meng, X., Kuhlman, J.R., Nelin, L.D., Nicol, K.K., English, B.K., Liu, Y. J. Immunol. (2007)
- MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Sun, H., Charles, C.H., Lau, L.F., Tonks, N.K. Cell (1993)
- Attenuation of virulence by disruption of the Mycobacterium tuberculosis erp gene. Berthet, F.X., Lagranderie, M., Gounon, P., Laurent-Winter, C., Ensergueix, D., Chavarot, P., Thouron, F., Maranghi, E., Pelicic, V., Portnoï, D., Marchal, G., Gicquel, B. Science (1998)
- Protein kinase Cdelta-mediated proteasomal degradation of MAP kinase phosphatase-1 contributes to glutamate-induced neuronal cell death. Choi, B.H., Hur, E.M., Lee, J.H., Jun, D.J., Kim, K.T. J. Cell. Sci. (2006)
- Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity. Wu, J.J., Roth, R.J., Anderson, E.J., Hong, E.G., Lee, M.K., Choi, C.S., Neufer, P.D., Shulman, G.I., Kim, J.K., Bennett, A.M. Cell metabolism. (2006)
- Differential regulation of p38 mitogen-activated protein kinase mediates gender-dependent catecholamine-induced hypertrophy. Dash, R., Schmidt, A.G., Pathak, A., Gerst, M.J., Biniakiewicz, D., Kadambi, V.J., Hoit, B.D., Abraham, W.T., Kranias, E.G. Cardiovasc. Res. (2003)
- Structure, mapping, and expression of erp, a growth factor-inducible gene encoding a nontransmembrane protein tyrosine phosphatase, and effect of ERP on cell growth. Noguchi, T., Metz, R., Chen, L., Mattéi, M.G., Carrasco, D., Bravo, R. Mol. Cell. Biol. (1993)
- The function of mitogen-activated protein kinase phosphatase-1 in peptidoglycan-stimulated macrophages. Shepherd, E.G., Zhao, Q., Welty, S.E., Hansen, T.N., Smith, C.V., Liu, Y. J. Biol. Chem. (2004)
- The noncatalytic amino terminus of mitogen-activated protein kinase phosphatase 1 directs nuclear targeting and serum response element transcriptional regulation. Wu, J.J., Zhang, L., Bennett, A.M. Mol. Cell. Biol. (2005)
- Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock. Hammer, M., Mages, J., Dietrich, H., Servatius, A., Howells, N., Cato, A.C., Lang, R. J. Exp. Med. (2006)
- Feedback regulation of Raf-1 and mitogen-activated protein kinase (MAP) kinase kinases 1 and 2 by MAP kinase phosphatase-1 (MKP-1). Shapiro, P.S., Ahn, N.G. J. Biol. Chem. (1998)
- Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling. Pouysségur, J., Lenormand, P. Eur. J. Biochem. (2003)
- Parathyroid hormone-related protein induces insulin expression through activation of MAP kinase-specific phosphatase-1 that dephosphorylates c-Jun NH2-terminal kinase in pancreatic beta-cells. Zhang, B., Hosaka, M., Sawada, Y., Torii, S., Mizutani, S., Ogata, M., Izumi, T., Takeuchi, T. Diabetes (2003)
- Extracellular signal-regulated kinase-2, but not c-Jun NH2-terminal kinase, activation correlates with surface IgM-mediated apoptosis in the WEHI 231 B cell line. Lee, J.R., Koretzky, G.A. J. Immunol. (1998)
- Role of extracellular signal-regulated protein kinase cascade in macrophage killing of Candida albicans. Ibata-Ombetta, S., Jouault, T., Trinel, P.A., Poulain, D. J. Leukoc. Biol. (2001)
- Macrophage colony-stimulating factor induces the expression of mitogen-activated protein kinase phosphatase-1 through a protein kinase C-dependent pathway. Valledor, A.F., Xaus, J., Marquès, L., Celada, A. J. Immunol. (1999)
- Angiotensin II type 2 receptor mediates programmed cell death. Yamada, T., Horiuchi, M., Dzau, V.J. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Mitogen-activated protein kinase phosphatase-1 represses c-Jun NH2-terminal kinase-mediated apoptosis via NF-kappaB regulation. Wang, Z., Cao, N., Nantajit, D., Fan, M., Liu, Y., Li, J.J. J. Biol. Chem. (2008)
- Molecular cloning and characterization of a novel dual specificity phosphatase, LMW-DSP2, that lacks the cdc25 homology domain. Aoyama, K., Nagata, M., Oshima, K., Matsuda, T., Aoki, N. J. Biol. Chem. (2001)
- Activation of ERK1/2 MAP kinases in familial amyloidotic polyneuropathy. Monteiro, F.A., Sousa, M.M., Cardoso, I., do Amaral, J.B., Guimarães, A., Saraiva, M.J. J. Neurochem. (2006)
- Expression of the nontransmembrane tyrosine phosphatase gene erp during mouse organogenesis. Carrasco, D., Bravo, R. Cell Growth Differ. (1993)
- Mitogen-activated protein kinase phosphatase-1 in olfactory neural regeneration. Shinogami, M., Ishibashi, T. Neuroreport (2000)