Gene Review:
Agtr2 - angiotensin II receptor, type 2
Mus musculus
Synonyms:
AI316812, AT2, AT2 receptor, AW107640, Angiotensin II type-2 receptor, ...
- Cardioprotective role of AT2 receptor in postinfarction left ventricular remodeling. Oishi, Y., Ozono, R., Yano, Y., Teranishi, Y., Akishita, M., Horiuchi, M., Oshima, T., Kambe, M. Hypertension (2003)
- Inflammation influences vascular remodeling through AT2 receptor expression and signaling. Akishita, M., Horiuchi, M., Yamada, H., Zhang, L., Shirakami, G., Tamura, K., Ouchi, Y., Dzau, V.J. Physiol. Genomics (2000)
- Possible inhibition of focal cerebral ischemia by angiotensin II type 2 receptor stimulation. Iwai, M., Liu, H.W., Chen, R., Ide, A., Okamoto, S., Hata, R., Sakanaka, M., Shiuchi, T., Horiuchi, M. Circulation (2004)
- Angiotensin II, type 2 receptor is not involved in the angiotensin II-mediated pro-atherogenic process in ApoE-/- mice. Johansson, M.E., Wickman, A., Fitzgerald, S.M., Gan, L.M., Bergström, G. J. Hypertens. (2005)
- Sustained hypersensitivity to angiotensin II and its mechanism in mice lacking the subtype-2 (AT2) angiotensin receptor. Siragy, H.M., Inagami, T., Ichiki, T., Carey, R.M. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Central angiotensin II controls alcohol consumption via its AT1 receptor. Maul, B., Krause, W., Pankow, K., Becker, M., Gembardt, F., Alenina, N., Walther, T., Bader, M., Siems, W.E. FASEB J. (2005)
- Effects of targeted disruption of the mouse angiotensin II type 2 receptor gene on stress-induced hyperthermia. Watanabe, T., Hashimoto, M., Okuyama, S., Inagami, T., Nakamura, S. J. Physiol. (Lond.) (1999)
- Pain threshold, learning and formation of brain edema in mice lacking the angiotensin II type 2 receptor. Sakagawa, T., Okuyama, S., Kawashima, N., Hozumi, S., Nakagawasai, O., Tadano, T., Kisara, K., Ichiki, T., Inagami, T. Life Sci. (2000)
- Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice. Hein, L., Barsh, G.S., Pratt, R.E., Dzau, V.J., Kobilka, B.K. Nature (1995)
- Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor. Ichiki, T., Labosky, P.A., Shiota, C., Okuyama, S., Imagawa, Y., Fogo, A., Niimura, F., Ichikawa, I., Hogan, B.L., Inagami, T. Nature (1995)
- Cardiac hypertrophy and fibrosis in chronic L-NAME-treated AT2 receptor-deficient mice. Gross, V., Obst, M., Kiss, E., Janke, J., Mazak, I., Shagdarsuren, E., Müller, D.N., Langenickel, T.H., Gröne, H.J., Luft, F.C. J. Hypertens. (2004)
- Heterogeneity of angiotensin II AT2 receptors in the rat brain. Tsutsumi, K., Saavedra, J.M. Mol. Pharmacol. (1992)
- Cloning, expression and regulation of angiotensin II receptors. Inagami, T., Iwai, N., Sasaki, K., Yamano, Y., Bardhan, S., Chaki, S., Guo, D.F., Furuta, H., Ohyama, K., Kambayashi, Y. Eur. Heart J. (1994)
- Angiotensin II AT2 receptors are functionally coupled to protein tyrosine dephosphorylation in N1E-115 neuroblastoma cells. Nahmias, C., Cazaubon, S.M., Briend-Sutren, M.M., Lazard, D., Villageois, P., Strosberg, A.D. Biochem. J. (1995)
- Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth. Akishita, M., Ito, M., Lehtonen, J.Y., Daviet, L., Dzau, V.J., Horiuchi, M. J. Clin. Invest. (1999)
- Linkage mapping of the angiotensin AT2 receptor gene (Agtr2) to the mouse X chromosome. Hein, L., Dzau, V.J., Barsh, G.S. Genomics (1995)
- Sex difference in vascular injury and the vasoprotective effect of valsartan are related to differential AT2 receptor expression. Okumura, M., Iwai, M., Ide, A., Mogi, M., Ito, M., Horiuchi, M. Hypertension (2005)
- Role of angiotensin in the development of the kidney and urinary tract. Pope, J.C., Nishimura, H., Ichikawa, I. Néphrologie. (1998)
- The growth-dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2. Horiuchi, M., Koike, G., Yamada, T., Mukoyama, M., Nakajima, M., Dzau, V.J. J. Biol. Chem. (1995)
- Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II. Oliverio, M.I., Kim, H.S., Ito, M., Le, T., Audoly, L., Best, C.F., Hiller, S., Kluckman, K., Maeda, N., Smithies, O., Coffman, T.M. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Angiotensin AT1B receptor mediates calcium signaling in vascular smooth muscle cells of AT1A receptor-deficient mice. Zhu, Z., Zhang, S.H., Wagner, C., Kurtz, A., Maeda, N., Coffman, T., Arendshorst, W.J. Hypertension (1998)
- Regulation of collagen synthesis in mouse skin fibroblasts by distinct angiotensin II receptor subtypes. Min, L.J., Cui, T.X., Yahata, Y., Yamasaki, K., Shiuchi, T., Liu, H.W., Chen, R., Li, J.M., Okumura, M., Jinno, T., Wu, L., Iwai, M., Nahmias, C., Hashimoto, K., Horiuchi, M. Endocrinology (2004)
- Genetic inactivation of the B2 receptor in mice worsens two-kidney, one-clip hypertension: role of NO and the AT2 receptor. Cervenka, L., Vanecková, I., Malý, J., Horácek, V., El-Dahr, S.S. J. Hypertens. (2003)
- Interferon regulatory factor-1 up-regulates angiotensin II type 2 receptor and induces apoptosis. Horiuchi, M., Yamada, T., Hayashida, W., Dzau, V.J. J. Biol. Chem. (1997)
- Changes in angiotensin II receptors in dopamine-rich regions of the mouse brain with age and ethanol consumption. Daubert, D.L., Meadows, G.G., Wang, J.H., Sanchez, P.J., Speth, R.C. Brain Res. (1999)
- Stimulation of different subtypes of angiotensin II receptors, AT1 and AT2 receptors, regulates STAT activation by negative crosstalk. Horiuchi, M., Hayashida, W., Akishita, M., Tamura, K., Daviet, L., Lehtonen, J.Y., Dzau, V.J. Circ. Res. (1999)
- Angiotensin AT2 receptors directly stimulate renal nitric oxide in bradykinin B2-receptor-null mice. Abadir, P.M., Carey, R.M., Siragy, H.M. Hypertension (2003)
- Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors. Bergaya, S., Hilgers, R.H., Meneton, P., Dong, Y., Bloch-Faure, M., Inagami, T., Alhenc-Gelas, F., Lévy, B.I., Boulanger, C.M. Circ. Res. (2004)
- Angiotensin II modulates renal sympathetic neurotransmission through nitric oxide in AT2 receptor knockout mice. Stegbauer, J., Vonend, O., Habbel, S., Quack, I., Sellin, L., Gross, V., Rump, L.C. J. Hypertens. (2005)
- AT2 receptor and vascular smooth muscle cell differentiation in vascular development. Yamada, H., Akishita, M., Ito, M., Tamura, K., Daviet, L., Lehtonen, J.Y., Dzau, V.J., Horiuchi, M. Hypertension (1999)
- Stimulation of cyclic GMP production via AT2 and B2 receptors in the pressure-overloaded aorta after banding. Hiyoshi, H., Yayama, K., Takano, M., Okamoto, H. Hypertension (2004)
- Angiotensin II receptor types 1A, 1B, and 2 in murine neuroblastoma Neuro-2a cells. Hoffmann, A., Cool, D.R. J. Recept. Signal Transduct. Res. (2003)
- Inhibition of pressure natriuresis in mice lacking the AT2 receptor. Gross, V., Schunck, W.H., Honeck, H., Milia, A.F., Kärgel, E., Walther, T., Bader, M., Inagami, T., Schneider, W., Luft, F.C. Kidney Int. (2000)
- Affinity purification of angiotensin type 2 receptors from N1E-115 cells: evidence for agonist-induced formation of multimeric complexes. Siemens, I.R., Yee, D.K., Reagan, L.P., Fluharty, S.J. J. Neurochem. (1994)