Gene Review:
Cpn1 - carboxypeptidase N, polypeptide 1
Mus musculus
Synonyms:
0610011F20Rik, 50 kDa, CPN, Carboxypeptidase N catalytic chain, Carboxypeptidase N polypeptide 1, ...
- Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis. Vlodavsky, I., Friedmann, Y., Elkin, M., Aingorn, H., Atzmon, R., Ishai-Michaeli, R., Bitan, M., Pappo, O., Peretz, T., Michal, I., Spector, L., Pecker, I. Nat. Med. (1999)
- The adenovirus E1A-regulated transcription factor E4F is generated from the human homolog of nuclear factor phiAP3. Fernandes, E.R., Rooney, R.J. Mol. Cell. Biol. (1997)
- A 50-kDa cytosolic protein complexed with the 90-kDa heat shock protein (hsp90) is the same protein complexed with pp60v-src hsp90 in cells transformed by the Rous sarcoma virus. Whitelaw, M.L., Hutchison, K., Perdew, G.H. J. Biol. Chem. (1991)
- Cloning and in vitro expression of a melanoma-associated antigen immunogenic in patients with melanoma. Hayashibe, K., Mishima, Y., Ferrone, S. J. Immunol. (1991)
- Analysis of mutants of tetanus toxin Hc fragment: ganglioside binding, cell binding and retrograde axonal transport properties. Sinha, K., Box, M., Lalli, G., Schiavo, G., Schneider, H., Groves, M., Siligardi, G., Fairweather, N. Mol. Microbiol. (2000)
- A brain detoxifying enzyme for organophosphorus nerve poisons. Nomura, D.K., Leung, D., Chiang, K.P., Quistad, G.B., Cravatt, B.F., Casida, J.E. Proc. Natl. Acad. Sci. U.S.A. (2005)
- A 12(S)-hydroxyeicosatetraenoic acid receptor interacts with steroid receptor coactivator-1. Kurahashi, Y., Herbertsson, H., Söderström, M., Rosenfeld, M.G., Hammarström, S. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Characterization of mammalian translocase of inner mitochondrial membrane (Tim44) isolated from diabetic newborn mouse kidney. Wada, J., Kanwar, Y.S. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Surface protein phosphorylation by ecto-protein kinase is required for the maintenance of hippocampal long-term potentiation. Chen, W., Wieraszko, A., Hogan, M.V., Yang, H.A., Kornecki, E., Ehrlich, Y.H. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Exon-intron organization and sequence comparison of human and murine T11 (CD2) genes. Diamond, D.J., Clayton, L.K., Sayre, P.H., Reinherz, E.L. Proc. Natl. Acad. Sci. U.S.A. (1988)
- A mutant pertussis toxin molecule that lacks ADP-ribosyltransferase activity, PT-9K/129G, is an effective mucosal adjuvant for intranasally delivered proteins. Roberts, M., Bacon, A., Rappuoli, R., Pizza, M., Cropley, I., Douce, G., Dougan, G., Marinaro, M., McGhee, J., Chatfield, S. Infect. Immun. (1995)
- Characterization of mouse carboxypeptidase N small active subunit gene structure. Matthews, K.W., Wetsel, R.A. J. Immunol. (2001)
- Expression of the third complement component (C3) and carboxypeptidase N small subunit (CPN1) during mouse embryonic development. Matthews, K.W., Drouin, S.M., Liu, C., Martin, J.F., Skidgel, R.A., Wetsel, R.A. Dev. Comp. Immunol. (2004)
- Identification, purification, and characterization of a mast cell-associated cytolytic factor related to tumor necrosis factor. Young, J.D., Liu, C.C., Butler, G., Cohn, Z.A., Galli, S.J. Proc. Natl. Acad. Sci. U.S.A. (1987)
- Bacterial lipopolysaccharides, phorbol myristate acetate, and zymosan induce the myristoylation of specific macrophage proteins. Aderem, A.A., Keum, M.M., Pure, E., Cohn, Z.A. Proc. Natl. Acad. Sci. U.S.A. (1986)
- Ectodomain shedding of preadipocyte factor 1 (Pref-1) by tumor necrosis factor alpha converting enzyme (TACE) and inhibition of adipocyte differentiation. Wang, Y., Sul, H.S. Mol. Cell. Biol. (2006)
- Identification and purification of a self-associating copper-binding protein from mouse hepatic cytosols. Seo, H.C., Ettinger, M.J. J. Biol. Chem. (1993)
- Identification of platelet membrane proteins that interact with amino-terminal peptides of pp60c-src. Feder, D., Bishop, J.M. J. Biol. Chem. (1991)
- Pro-carboxypeptidase R is an acute phase protein in the mouse, whereas carboxypeptidase N is not. Sato, T., Miwa, T., Akatsu, H., Matsukawa, N., Obata, K., Okada, N., Campbell, W., Okada, H. J. Immunol. (2000)
- Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1alpha in the circulation. Davis, D.A., Singer, K.E., De La Luz Sierra, M., Narazaki, M., Yang, F., Fales, H.M., Yarchoan, R., Tosato, G. Blood (2005)
- Differentiation of 3T3-L1 preadipocytes with 3-isobutyl-1-methylxanthine and dexamethasone stimulates cell-associated and soluble chondroitin 4-sulfate proteoglycans. Calvo, J.C., Rodbard, D., Katki, A., Chernick, S., Yanagishita, M. J. Biol. Chem. (1991)
- The predominant form of secreted colony stimulating factor-1 is a proteoglycan. Price, L.K., Choi, H.U., Rosenberg, L., Stanley, E.R. J. Biol. Chem. (1992)
- Structure/function relationships in hexokinase. Site-directed mutational analyses and characterization of overexpressed fragments implicate different functions for the N- and C-terminal halves of the enzyme. Arora, K.K., Filburn, C.R., Pedersen, P.L. J. Biol. Chem. (1993)
- Metabolic activation and immunochemical localization of liver protein adducts of the nonsteroidal anti-inflammatory drug diclofenac. Hargus, S.J., Amouzedeh, H.R., Pumford, N.R., Myers, T.G., McCoy, S.C., Pohl, L.R. Chem. Res. Toxicol. (1994)
- Deoxyribonucleic acid-protein interactions associated with transcriptional initiation of the mouse testis-specific cytochrome c gene. Yiu, G.K., Murray, M.T., Hecht, N.B. Biol. Reprod. (1997)
- Two distinct porcine natural killer lytic trigger molecules as PNK-E/G7 molecular complex. Wierda, W.G., Johnson, B.D., Dato, M.E., Kim, Y.B. Cell. Immunol. (1993)
- Vimentin phosphorylation by p37mos protein kinase in vitro and generation of a 50-kDa cleavage product in v-mos-transformed cells. Singh, B., Arlinghaus, R.B. Virology (1989)
- The in vivo biosynthesis of embryonic proteins after maternal administration of phenytoin in the mouse. Hicks, H.E., Banes, A.J. Proc. Soc. Exp. Biol. Med. (1985)
- The acetaminophen regioisomer 3'-hydroxyacetanilide inhibits and covalently binds to cytochrome P450 2E1. Halmes, N.C., Samokyszyn, V.M., Hinton, T.W., Hinson, J.A., Pumford, N.R. Toxicol. Lett. (1998)
- Asb6, an adipocyte-specific ankyrin and SOCS box protein, interacts with APS to enable recruitment of elongins B and C to the insulin receptor signaling complex. Wilcox, A., Katsanakis, K.D., Bheda, F., Pillay, T.S. J. Biol. Chem. (2004)
- Separate elements in the 3' untranslated region of the mouse protamine 1 mRNA regulate translational repression and activation during murine spermatogenesis. Fajardo, M.A., Haugen, H.S., Clegg, C.H., Braun, R.E. Dev. Biol. (1997)
- Effects of recombinant insulin-like growth factor-binding protein-4 on bone formation parameters in mice. Miyakoshi, N., Richman, C., Qin, X., Baylink, D.J., Mohan, S. Endocrinology (1999)
- Gene 33/RALT is induced by hypoxia in cardiomyocytes, where it promotes cell death by suppressing phosphatidylinositol 3-kinase and extracellular signal-regulated kinase survival signaling. Xu, D., Patten, R.D., Force, T., Kyriakis, J.M. Mol. Cell. Biol. (2006)
- Characterization of transforming growth factors produced by the insulin-independent teratoma-derived cell line 1246-3A. Yamada, Y., Serrero, G. J. Cell. Physiol. (1989)
- Structure of the gene encoding mouse adipose differentiation-related protein (ADRP). Eisinger, D.P., Serrero, G. Genomics (1993)
- Cytochrome P450 isoforms in human fetal tissues related to phenobarbital-inducible forms in the mouse. Mäenpää, J., Rane, A., Raunio, H., Honkakoski, P., Pelkonen, O. Biochem. Pharmacol. (1993)
- Further characterization of the interaction between L-selectin and its endothelial ligands. Imai, Y., Lasky, L.A., Rosen, S.D. Glycobiology (1992)
- A 50-kDa ERK-like protein is up-regulated by a dual altered peptide ligand that suppresses myasthenia gravis-associated responses. Ben-David, H., Aruna, B.V., Seger, R., Sela, M., Mozes, E. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Identification of a 30-base pair regulatory element and novel DNA binding protein that regulates the human GLUT4 promoter in transgenic mice. Oshel, K.M., Knight, J.B., Cao, K.T., Thai, M.V., Olson, A.L. J. Biol. Chem. (2000)
- Anti-KCA-3, a monoclonal antibody reactive with a rat complement C3 receptor, distinguishes Kupffer cells from other macrophages. Maruiwa, M., Mizoguchi, A., Russell, G.J., Narula, N., Stronska, M., Mizoguchi, E., Rabb, H., Arnaout, M.A., Bhan, A.K. J. Immunol. (1993)
- Macrophage formation of angiostatin during inflammation. A byproduct of the activation of plasminogen. Falcone, D.J., Khan, K.M., Layne, T., Fernandes, L. J. Biol. Chem. (1998)