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MeSH Review

Models, Statistical

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Disease relevance of Models, Statistical


Psychiatry related information on Models, Statistical


High impact information on Models, Statistical

  • Structural parameters characterizing the bending propensity of trinucleotides were deduced from DNase I digestion data using simple probabilistic models [11].
  • In this study we compared the goodness-of-fit of each theory with a probabilistic model of exon/intron evolution and multiple nonallelic genes encoding human aldehyde dehydrogenases (ALDHs) [12].
  • PATIENTS AND METHODS: Data from 934 patients treated between 1987 and 2000 were used to develop a comprehensive statistical model to fit the clinical recurrence events and patterns of PSA data [13].
  • Lod scores of < -2.0 were generated for the entire region, thus excluding PTEN and any genes within the flanking 20-cM interval as candidate loci for familial JPS under our statistical models [14].
  • The number of TM-positive vessels correlated with all parameters of radiation enteropathy and, after adjusting for radiation dose and observation time in a statistical model, remained independently associated with neutrophil infiltration, intestinal wall thickening, and collagen I accumulation [15].

Chemical compound and disease context of Models, Statistical


Biological context of Models, Statistical


Anatomical context of Models, Statistical

  • Multivariate statistical models revealed a highly significant relationship between NDMA levels and urinary nitrate, stimulation indices for two T cell responses to two parasite antigens (MW 37 kDa and 110 kDa) and gall bladder dimensions [24].
  • To overcome the difficulties associated with non-parametric phase unwrapping due to thoracic anti-resonances, the phase delay tau(f) of propagation between the trachea and the chest wall is estimated using a linear parametric ARX-type statistical model with the non-parametric magnitude spectra as a guide [25].
  • Among the linear, parabolic, and polynomial models tested, 3rd- and 4th-order polynomial models of regression exerted best correlations between the time and histamine-induced gastric acid secretion [26].
  • In human IPF lungs, osteopontin colocalized with MMP-7 in alveolar epithelial cells, and application of weakest link statistical models to microarray data suggested a significant interaction between osteopontin and MMP-7 [27].

Associations of Models, Statistical with chemical compounds

  • CONCLUSIONS: Using this statistical model, the chances of postoperative dialysis can be estimated exactly before operation; age and preoperative serum creatinine level are the only variables predictive for postoperative dialysis [28].
  • Fitting the length distributions at intermediate ethanol concentrations to a simple binomial model results in an upper bound estimate for the A-form and B-form domains of approximately 54 bp in the individual molecules [29].
  • Plasma NPY maintained its predictive power for CV events in statistical model including plasma norepinephrine [30].
  • CONCLUSIONS: To evaluate accuracy of blood glucose meters, error grid analysis, as well as statistical models, are helpful means and should be performed together [31].
  • In a multivariate statistical model, among the following variables: sex, age, systolic BP, diastolic BP, cholesterol and smoking, systolic BP was found the best predictor of extent and severity of atherosclerotic lesions at extracranial level [32].

Gene context of Models, Statistical

  • Ultimately, the data for all five CYPs and the recombinant CYP2D6 were used to build a statistical model for predicting the IC(50) with a single point [33].
  • OBJECTIVE: To test whether statistical models developed to calculate pre-test probability of being a BRCA1/2 carrier can differentiate better between the breast/ovarian families to be referred to the DNA test laboratory [34].
  • OBJECTIVES: To characterize the clinical predictors, spectrum, and frequency of BRCA1 and BRCA2 mutations in an ethnically diverse high-risk clinic population and to evaluate the performance of the BRCAPRO statistical model in predicting the likelihood of a mutation [35].
  • These findings were confirmed by multiple regression, taking into consideration additional information about the patients to build statistical models allowing prediction of AR [36].
  • TNF-alpha (standardised coefficient beta = 0.410, p<0.001) and IL-1beta (standardised coefficient beta = 0.311, p = 0.006) were most strongly associated with the degree of lung injury, even when the diagnostic group was included in the statistical model [37].

Analytical, diagnostic and therapeutic context of Models, Statistical


  1. Galactocerebrosidase activity in canine globoid leukodystrophy. Fletcher, T.F., Suzuki, K., Martin, F.B. Neurology (1977) [Pubmed]
  2. Stimulant treatment over 5 years: effects on growth. Charach, A., Figueroa, M., Chen, S., Ickowicz, A., Schachar, R. Journal of the American Academy of Child and Adolescent Psychiatry. (2006) [Pubmed]
  3. Hospitalization rates for coronary heart disease in relation to residence near areas contaminated with persistent organic pollutants and other pollutants. Sergeev, A.V., Carpenter, D.O. Environ. Health Perspect. (2005) [Pubmed]
  4. Plasma triglyceride as a risk factor for coronary heart disease. The epidemiologic evidence and beyond. Austin, M.A. Am. J. Epidemiol. (1989) [Pubmed]
  5. Pharmacokinetics of mycophenolic acid in renal transplant patients with delayed graft function. Shaw, L.M., Mick, R., Nowak, I., Korecka, M., Brayman, K.L. Journal of clinical pharmacology. (1998) [Pubmed]
  6. Hepatitis C virus infection is an additive risk factor for development of hepatocellular carcinoma in patients with cirrhosis. Caporaso, N., Romano, M., Marmo, R., de Sio, I., Morisco, F., Minerva, A., Coltorti, M. J. Hepatol. (1991) [Pubmed]
  7. Diagnostic boundaries, reasoning and depressive disorder, II. Application of a probabilistic model to the OPCS general population survey of psychiatric morbidity in Great Britain. Surtees, P.G., Wainwright, N.W., Gilks, W.R., Brugha, T.S., Meltzer, H., Jenkins, R. Psychological medicine. (1997) [Pubmed]
  8. The role of drug and alcohol abuse in recent increases in depression in the US. Klerman, G.L., Leon, A.C., Wickramaratne, P., Warshaw, M.G., Mueller, T.I., Weissman, M.M., Akiskal, H. Psychological medicine. (1996) [Pubmed]
  9. Interpersonal feedback: a social relations perspective. Marcus, D.K. International journal of group psychotherapy. (2006) [Pubmed]
  10. Sleep in rheumatoid arthritis: a comparison with healthy subjects and studies of sleep/wake interactions. Drewes, A.M., Svendsen, L., Taagholt, S.J., Bjerregård, K., Nielsen, K.D., Hansen, B. Br. J. Rheumatol. (1998) [Pubmed]
  11. Sequence-dependent bending propensity of DNA as revealed by DNase I: parameters for trinucleotides. Brukner, I., Sánchez, R., Suck, D., Pongor, S. EMBO J. (1995) [Pubmed]
  12. Exon/intron structure of aldehyde dehydrogenase genes supports the "introns-late" theory. Rzhetsky, A., Ayala, F.J., Hsu, L.C., Chang, C., Yoshida, A. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  13. Individualized predictions of disease progression following radiation therapy for prostate cancer. Taylor, J.M., Yu, M., Sandler, H.M. J. Clin. Oncol. (2005) [Pubmed]
  14. Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome. Marsh, D.J., Roth, S., Lunetta, K.L., Hemminki, A., Dahia, P.L., Sistonen, P., Zheng, Z., Caron, S., van Orsouw, N.J., Bodmer, W.F., Cottrell, S.E., Dunlop, M.G., Eccles, D., Hodgson, S.V., Järvinen, H., Kellokumpu, I., Markie, D., Neale, K., Phillips, R., Rozen, P., Syngal, S., Vijg, J., Tomlinson, I.P., Aaltonen, L.A., Eng, C. Cancer Res. (1997) [Pubmed]
  15. Deficiency of microvascular thrombomodulin and up-regulation of protease-activated receptor-1 in irradiated rat intestine: possible link between endothelial dysfunction and chronic radiation fibrosis. Wang, J., Zheng, H., Ou, X., Fink, L.M., Hauer-Jensen, M. Am. J. Pathol. (2002) [Pubmed]
  16. Frequency distribution of Echinococcus granulosus hydatid cysts in sheep populations in the Xinjiang Uygur Autonomous Region, China. Ming, R., Tolley, H.D., Andersen, F.L., Chai, J., Sultan, Y. Vet. Parasitol. (1992) [Pubmed]
  17. Evaluation of alternative statistical models for crossover studies to demonstrate caffeine adjuvancy in the treatment of tension headache. Koch, G.G., Amara, I.A., MacMillan, J. Journal of biopharmaceutical statistics. (1994) [Pubmed]
  18. Does the time course of bubble evolution explain decompression sickness risk? Ball, R., Himm, J., Homer, L.D., Thalmann, E.D. Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc. (1995) [Pubmed]
  19. Thiocyanate-independent nitrosation in humans with carcinogenic parasite infection. Satarug, S., Haswell-Elkins, M.R., Tsuda, M., Mairiang, P., Sithithaworn, P., Mairiang, E., Esumi, H., Sukprasert, S., Yongvanit, P., Elkins, D.B. Carcinogenesis (1996) [Pubmed]
  20. Segregation ratios within Segregation Distorter lines of Drosophila melanogaster conform to a beta-binomial distribution. Sharp, C.B., Hilliker, A.J. Genet. Res. (1990) [Pubmed]
  21. Use of a highly purified alpha 1-antitrypsin standard to establish ranges for the common normal and deficient alpha 1-antitrypsin phenotypes. Brantly, M.L., Wittes, J.T., Vogelmeier, C.F., Hubbard, R.C., Fells, G.A., Crystal, R.G. Chest (1991) [Pubmed]
  22. Pharmacokinetics of thalidomide in patients with impaired renal function and while on and off dialysis. Eriksson, T., Höglund, P., Turesson, I., Waage, A., Don, B.R., Vu, J., Scheffler, M., Kaysen, G.A. J. Pharm. Pharmacol. (2003) [Pubmed]
  23. Influence of pH, malic acid and glucose concentrations on malic acid consumption by Saccharomyces cerevisiae. Delcourt, F., Taillandier, P., Vidal, F., Strehaiano, P. Appl. Microbiol. Biotechnol. (1995) [Pubmed]
  24. Relationships between the synthesis of N-nitrosodimethylamine and immune responses to chronic infection with the carcinogenic parasite, Opisthorchis viverrini, in men. Satarug, S., Haswell-Elkins, M.R., Sithithaworn, P., Bartsch, H., Ohshima, H., Tsuda, M., Mairiang, P., Mairiang, E., Yongvanit, P., Esumi, H., Elkins, D.B. Carcinogenesis (1998) [Pubmed]
  25. Parametric phase-delay estimation of sound transmitted through intact human lung. Lu, S., Doerschuk, P.C., Wodicka, G.R. Medical & biological engineering & computing. (1995) [Pubmed]
  26. Biostatistical modeling of the effect of intravenous histamine-infusion on the rat gastric acid secretion. Ozçelikay, A.T., Altinkurt, O., Oztürk, Y., Yildizoğlu-Ari, N., Altan, V.M. Journal of pharmacological methods. (1990) [Pubmed]
  27. Up-regulation and profibrotic role of osteopontin in human idiopathic pulmonary fibrosis. Pardo, A., Gibson, K., Cisneros, J., Richards, T.J., Yang, Y., Becerril, C., Yousem, S., Herrera, I., Ruiz, V., Selman, M., Kaminski, N. PLoS Med. (2005) [Pubmed]
  28. Risk assessment of acute renal failure after thoracoabdominal aortic aneurysm surgery. Schepens, M.A., Defauw, J.J., Hamerlijnck, R.P., Vermeulen, F.E. Ann. Surg. (1994) [Pubmed]
  29. Ethanol-induced structural transitions of DNA on mica. Fang, Y., Spisz, T.S., Hoh, J.H. Nucleic Acids Res. (1999) [Pubmed]
  30. Prospective study of neuropeptide y as an adverse cardiovascular risk factor in end-stage renal disease. Zoccali, C., Mallamaci, F., Tripepi, G., Benedetto, F.A., Parlongo, S., Cutrupi, S., Iellamo, D., Bonanno, G., Rapisarda, F., Fatuzzo, P., Seminara, G., Cataliotti, A., Malatino, L.S. J. Am. Soc. Nephrol. (2003) [Pubmed]
  31. Validation of home blood glucose meters with respect to clinical and analytical approaches. Brunner, G.A., Ellmerer, M., Sendlhofer, G., Wutte, A., Trajanoski, Z., Schaupp, L., Quehenberger, F., Wach, P., Krejs, G.J., Pieber, T.R. Diabetes Care (1998) [Pubmed]
  32. The Italian Multicenter Study of reversible cerebral ischemic attacks: IV--Blood pressure components and atherosclerotic lesions. Inzitari, D., Bianchi, F., Pracucci, G., Albanese, V., Argentino, C., Bono, G., Brambilla, G.L., Candelise, L., De Zanche, L., Mariani, F. Stroke (1986) [Pubmed]
  33. Optimizing higher throughput methods to assess drug-drug interactions for CYP1A2, CYP2C9, CYP2C19, CYP2D6, rCYP2D6, and CYP3A4 in vitro using a single point IC(50). Gao, F., Johnson, D.L., Ekins, S., Janiszewski, J., Kelly, K.G., Meyer, R.D., West, M. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening. (2002) [Pubmed]
  34. Pre-test prediction models of BRCA1 or BRCA2 mutation in breast/ovarian families attending familial cancer clinics. de la Hoya, M., Díez, O., Pérez-Segura, P., Godino, J., Fernández, J.M., Sanz, J., Alonso, C., Baiget, M., Díaz-Rubio, E., Caldés, T. J. Med. Genet. (2003) [Pubmed]
  35. Genetic testing in an ethnically diverse cohort of high-risk women: a comparative analysis of BRCA1 and BRCA2 mutations in American families of European and African ancestry. Nanda, R., Schumm, L.P., Cummings, S., Fackenthal, J.D., Sveen, L., Ademuyiwa, F., Cobleigh, M., Esserman, L., Lindor, N.M., Neuhausen, S.L., Olopade, O.I. JAMA (2005) [Pubmed]
  36. Androgen, estrogen, and progesterone receptor levels in malignant and benign breast tumors: a multivariate analysis approach. Brentani, M.M., Franco, E.L., Oshima, C.T., Pacheco, M.M. Int. J. Cancer (1986) [Pubmed]
  37. Comparison of systemic cytokine levels in patients with acute respiratory distress syndrome, severe pneumonia, and controls. Bauer, T.T., Montón, C., Torres, A., Cabello, H., Fillela, X., Maldonado, A., Nicolás, J.M., Zavala, E. Thorax (2000) [Pubmed]
  38. Prospectively packaged lymph node dissections with radical cystectomy: evaluation of node count variability and node mapping. Bochner, B.H., Cho, D., Herr, H.W., Donat, M., Kattan, M.W., Dalbagni, G. J. Urol. (2004) [Pubmed]
  39. Plasma levels of enterolactone and percentage mammographic density among postmenopausal women. Stuedal, A., Gram, I.T., Bremnes, Y., Adlercreutz, H., Veierød, M.B., Ursin, G. Cancer Epidemiol. Biomarkers Prev. (2005) [Pubmed]
  40. The accuracy of outcome prediction models for childhood-onset epilepsy. Geelhoed, M., Boerrigter, A.O., Camfield, P., Geerts, A.T., Arts, W., Smith, B., Camfield, C. Epilepsia (2005) [Pubmed]
  41. Evaluation of a statistical model for the formation of poly [acryloyl hydroxyethyl starch] microspheres. Huang, L.K., Mehta, R.C., DeLuca, P.P. Pharm. Res. (1997) [Pubmed]
  42. BCI Competition 2003--Data set III: probabilistic modeling of sensorimotor mu rhythms for classification of imaginary hand movements. Lemm, S., Schäfer, C., Curio, G. IEEE transactions on bio-medical engineering. (2004) [Pubmed]
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