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Chemical Compound Review

Hermaphrodiol     (3S,8S,9S,10R,13S,14S,17S)- 10,13-dimethyl...

Synonyms: Tetrabol, Neumune, Androstenediol, Delta 5-Androstenediol, 5-Androstene-3,17-diol, ...
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Disease relevance of Hermaphrodiol


Psychiatry related information on Hermaphrodiol

  • Plasma androstenediol levels increased significantly in the anorexia nervosa patients at 12.00 (P less than 0.001), 14.00 (P less than 0.01) and 16.00 h (P less than 0.01) in response to LH [6].

High impact information on Hermaphrodiol


Chemical compound and disease context of Hermaphrodiol


Biological context of Hermaphrodiol


Anatomical context of Hermaphrodiol


Associations of Hermaphrodiol with other chemical compounds


Gene context of Hermaphrodiol


Analytical, diagnostic and therapeutic context of Hermaphrodiol


  1. Androstenediol antagonizes herpes simplex virus type 1-induced encephalitis through the augmentation of type I IFN production. Daigle, J., Carr, D.J. J. Immunol. (1998) [Pubmed]
  2. A role of PPAR-gamma in androstenediol-mediated salutary effects on cardiac function following trauma-hemorrhage. Shimizu, T., Szalay, L., Hsieh, Y.C., Suzuki, T., Choudhry, M.A., Bland, K.I., Chaudry, I.H. Ann. Surg. (2006) [Pubmed]
  3. Identification of steroid derivatives that function as potent antiandrogens. Miyamoto, H., Marwah, P., Marwah, A., Yang, Z., Chung, C.Y., Altuwaijri, S., Chang, C., Lardy, H. Int. J. Cancer (2005) [Pubmed]
  4. Androstenediol administration after trauma-hemorrhage attenuates inflammatory response, reduces organ damage, and improves survival following sepsis. Szalay, L., Shimizu, T., Suzuki, T., Hsieh, Y.C., Choudhry, M.A., Schwacha, M.G., Bland, K.I., Chaudry, I.H. Am. J. Physiol. Gastrointest. Liver Physiol. (2006) [Pubmed]
  5. Interactions between hormone-mediated and vaccine-mediated immunotherapy for pulmonary tuberculosis in BALB/c mice. Hernandez-Pando, R., Pavon, L., Orozco, E.H., Rangel, J., Rook, G.A. Immunology (2000) [Pubmed]
  6. Effect of human pituitary luteinizing hormone administration on plasma levels of dehydroepiandrosterone, androstenediol and their sulphates and testosterone in women with secondary amenorrhoea. Sirinathsinghji, D.J., Mills, I.H. J. Endocrinol. (1983) [Pubmed]
  7. Serum hormones and the alcohol-breast cancer association in postmenopausal women. Dorgan, J.F., Baer, D.J., Albert, P.S., Judd, J.T., Brown, E.D., Corle, D.K., Campbell, W.S., Hartman, T.J., Tejpar, A.A., Clevidence, B.A., Giffen, C.A., Chandler, D.W., Stanczyk, F.Z., Taylor, P.R. J. Natl. Cancer Inst. (2001) [Pubmed]
  8. 3 beta-acetoxyandrost-1,5-diene-17-ethylene ketal functions as a potent antiandrogen with marginal agonist activity. Miyamoto, H., Marwah, P., Marwah, A., Lardy, H., Chang, C. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  9. The Andro Project: physiological and hormonal influences of androstenedione supplementation in men 35 to 65 years old participating in a high-intensity resistance training program. Broeder, C.E., Quindry, J., Brittingham, K., Panton, L., Thomson, J., Appakondu, S., Breuel, K., Byrd, R., Douglas, J., Earnest, C., Mitchell, C., Olson, M., Roy, T., Yarlagadda, C. Arch. Intern. Med. (2000) [Pubmed]
  10. Phase I study of STX 64 (667 Coumate) in breast cancer patients: the first study of a steroid sulfatase inhibitor. Stanway, S.J., Purohit, A., Woo, L.W., Sufi, S., Vigushin, D., Ward, R., Wilson, R.H., Stanczyk, F.Z., Dobbs, N., Kulinskaya, E., Elliott, M., Potter, B.V., Reed, M.J., Coombes, R.C. Clin. Cancer Res. (2006) [Pubmed]
  11. The relationship between oestradiol metabolism and adrenal steroids in the endometrium of postmenopausal women with and without endometrial cancer. Bonney, R.C., Scanlon, M.J., Jones, D.L., Reed, M.J., Anderson, M.C., James, V.H. European journal of cancer & clinical oncology. (1986) [Pubmed]
  12. Serum concentration of androstenediol and androstenediol sulfate in patients with hyperthyroidism and hypothyroidism. Tagawa, N., Takano, T., Fukata, S., Kuma, K., Tada, H., Izumi, Y., Kobayashi, Y., Amino, N. Endocr. J. (2001) [Pubmed]
  13. Mechanism of salutary effects of androstenediol on hepatic function after trauma-hemorrhage: role of endothelial and inducible nitric oxide synthase. Shimizu, T., Szalay, L., Choudhry, M.A., Schwacha, M.G., Rue, L.W., Bland, K.I., Chaudry, I.H. Am. J. Physiol. Gastrointest. Liver Physiol. (2005) [Pubmed]
  14. Breast cancer: from estrogen to androgen receptor. Andò, S., De Amicis, F., Rago, V., Carpino, A., Maggiolini, M., Panno, M.L., Lanzino, M. Mol. Cell. Endocrinol. (2002) [Pubmed]
  15. Immune up-regulation and tumor apoptosis by androstene steroids. Loria, R.M. Steroids (2002) [Pubmed]
  16. Androstenediol reduces the anti-inflammatory effects of restraint stress during wound healing. Head, C.C., Farrow, M.J., Sheridan, J.F., Padgett, D.A. Brain Behav. Immun. (2006) [Pubmed]
  17. Adrenal androgen concentrations in endometrium and plasma during the menstrual cycle. Bonney, R.C., Scanlon, M.J., Jones, D.L., Reed, M.J., James, V.H. J. Endocrinol. (1984) [Pubmed]
  18. Studies on phenolic steriods in human subjects. XXI. renal metabolism, conjugation and excretion of four androgens: a comparison with estriol. Kirdani, R., Barua, N.R., Sandberg, A.A. J. Clin. Endocrinol. Metab. (1977) [Pubmed]
  19. Androgen biosynthesis in the stomach: expression of cytochrome P450 17 alpha-hydroxylase/17,20-lyase messenger ribonucleic acid and protein, and metabolism of pregnenolone and progesterone by parietal cells of the rat gastric mucosa. Le Goascogne, C., Sananès, N., Eychenne, B., Gouézou, M., Baulieu, E.E., Robel, P. Endocrinology (1995) [Pubmed]
  20. Increased levels of IFN-gamma in the trigeminal ganglion correlate with protection against HSV-1-induced encephalitis following subcutaneous administration with androstenediol. Carr, D.J. J. Neuroimmunol. (1998) [Pubmed]
  21. In vivo radioprotection by 5-androstenediol: stimulation of the innate immune system. Whitnall, M.H., Inal, C.E., Jackson, W.E., Miner, V.L., Villa, V., Seed, T.M. Radiat. Res. (2001) [Pubmed]
  22. Studies of the human testis. V. Properties of delta-5-3beta and 17beta-hydroxysteroid dehydrogenases in the biosynthesis of testosterone from dehydroepiandrosterone]. Oshima, H., Fan, D.F., Troen, P. J. Clin. Endocrinol. Metab. (1975) [Pubmed]
  23. Plasma lipoprotein profile in the male cynomolgus monkey under normal, hypogonadal, and combined androgen blockade conditions. Leblanc, M., Bélanger, M.C., Julien, P., Tchernof, A., Labrie, C., Bélanger, A., Labrie, F. J. Clin. Endocrinol. Metab. (2004) [Pubmed]
  24. Sex steroid metabolism in human peripheral blood mononuclear cells changes with aging. Hammer, F., Drescher, D.G., Schneider, S.B., Quinkler, M., Stewart, P.M., Allolio, B., Arlt, W. J. Clin. Endocrinol. Metab. (2005) [Pubmed]
  25. cyp7b1 catalyses the 7alpha-hydroxylation of dehydroepiandrosterone and 25-hydroxycholesterol in rat prostate. Martin, C., Bean, R., Rose, K., Habib, F., Seckl, J. Biochem. J. (2001) [Pubmed]
  26. Effect of estrogen receptor agonists treatment in MPTP mice: evidence of neuroprotection by an ER alpha agonist. D'Astous, M., Morissette, M., Di Paolo, T. Neuropharmacology (2004) [Pubmed]
  27. Estrogen and androgen receptor mediated stimulation and inhibition of proliferation by androst-5-ene-3 beta,17 beta-diol in human mammary cancer cells. Hackenberg, R., Turgetto, I., Filmer, A., Schulz, K.D. J. Steroid Biochem. Mol. Biol. (1993) [Pubmed]
  28. Adrenal androgens and human breast cancer: a new appraisal. Adams, J.B. Breast Cancer Res. Treat. (1998) [Pubmed]
  29. Dehydroepiandrosterone (DHEA) modulates GHRH, somatostatin and angiotensin II action at the pituitary level. Suárez, C., Vela, J., García-Tornadú, I., Becu-Villalobos, D. J. Endocrinol. (2005) [Pubmed]
  30. Androstenedione and androst-5-ene-3 beta,17 beta-diol stimulate DMBA-induced rat mammary tumors--role of aromatase. Dauvois, S., Labrie, F. Breast Cancer Res. Treat. (1989) [Pubmed]
  31. Heterologous enzyme immunoassay for serum androstenediol. Tagawa, N., Tamanaka, J., Fujinami, A., Kiguchi, T., Naito, T., Takano, T., Amino, N., Kobayashi, Y. Clin. Chim. Acta (2000) [Pubmed]
  32. Androstenediol-induced restoration of responsiveness to influenza vaccination in mice. Padgett, D.A., MacCallum, R.C., Loria, R.M., Sheridan, J.F. J. Gerontol. A Biol. Sci. Med. Sci. (2000) [Pubmed]
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