Chemical Compound Review:
Actinex 4-[(2S,3R)-4-(3,4- dihydroxyphenyl)-2,3...
Synonyms:
Masoprocol, Masoprocolum, NDGA, meso-NDGA, Lopac-N-5023, ...
- Effect of masoprocol on carbohydrate and lipid metabolism in a rat model of Type II diabetes. Reed, M.J., Meszaros, K., Entes, L.J., Claypool, M.D., Pinkett, J.G., Brignetti, D., Luo, J., Khandwala, A., Reaven, G.M. Diabetologia (1999)
- Antiviral activities of methylated nordihydroguaiaretic acids. 2. Targeting herpes simplex virus replication by the mutation insensitive transcription inhibitor tetra-O-methyl-NDGA. Chen, H., Teng, L., Li, J.N., Park, R., Mold, D.E., Gnabre, J., Hwu, J.R., Tseng, W.N., Huang, R.C. J. Med. Chem. (1998)
- A double-blind, vehicle-controlled study evaluating masoprocol cream in the treatment of actinic keratoses on the head and neck. Olsen, E.A., Abernethy, M.L., Kulp-Shorten, C., Callen, J.P., Glazer, S.D., Huntley, A., McCray, M., Monroe, A.B., Tschen, E., Wolf, J.E. J. Am. Acad. Dermatol. (1991)
- Masoprocol lowers blood pressure in rats with fructose-induced hypertension. Gowri, M.S., Reaven, G.M., Azhar, S. Am. J. Hypertens. (1999)
- Involvement of phospholipase A2 and lipoxygenase in lipopolysaccharide-induced inducible nitric oxide synthase expression in glial cells. Won, J.S., Im, Y.B., Khan, M., Singh, A.K., Singh, I. Glia (2005)
- Antiviral activities of methylated nordihydroguaiaretic acids. 1. Synthesis, structure identification, and inhibition of tat-regulated HIV transactivation. Hwu, J.R., Tseng, W.N., Gnabre, J., Giza, P., Huang, R.C. J. Med. Chem. (1998)
- Inhibition of steroid production in Leydig cells by non-steroidal anti-inflammatory and related compounds: evidence for the involvement of lipoxygenase products in steroidogenesis. Dix, C.J., Habberfield, A.D., Sullivan, M.H., Cooke, B.A. Biochem. J. (1984)
- Masoprocol decreases rat lipolytic activity by decreasing the phosphorylation of HSL. Gowri, M.S., Azhar, R.K., Kraemer, F.B., Reaven, G.M., Azhar, S. Am. J. Physiol. Endocrinol. Metab. (2000)
- Sulphasalazine and derivatives, natural killer activity and ulcerative colitis. Gibson, P.R., Jewell, D.P. Clin. Sci. (1985)
- Stimulation of progesterone secretion in dispersed cells of rat corpora lutea by antioxidants. Carlson, J.C., Sawada, M., Boone, D.L., Stauffer, J.M. Steroids (1995)
- Interleukin-3 and interleukin-6 stimulate bovine adrenal cortisol secretion through different pathways. Michl, P., Beikler, T., Engelhardt, D., Weber, M.M. J. Neuroendocrinol. (2000)
- Inhibitors of lipoxygenase increase the ovulation rate in the in-vitro perfused luteinizing hormone-stimulated rabbit ovary. Hellberg, P., Holmes, P.V., Brännström, M., Olofsson, J., Janson, P.O. Acta Physiol. Scand. (1990)
- Reactive oxygen species and not lipoxygenase products are required for mouse B-lymphocyte activation and differentiation. Fedyk, E.R., Phipps, R.P. Int. J. Immunopharmacol. (1994)
- Contributions of inflammatory mast cell mediators to alterations in macrophage function after malathion administration. Rodgers, K., Xiong, S. Int. J. Immunopharmacol. (1997)
- Anti-inflammatory activity of a dual inhibitor of cyclooxygenase and lipoxygenase pathways, CBS-1108 (2-acetylthiophene-2-thiazolylhydrazone). Sincholle, D., Bertez, C., Legrand, A., Conduzorgues, J.P., Bonne, C. Arzneimittel-Forschung. (1985)
- Excitotoxin induction of ornithine decarboxylase in cerebral cortex is reduced by phospholipase A2 inhibition. Gardiner, I.M., Li, A., Patel, N., Ball, S., de Belleroche, J. Life Sci. (1992)
- Effect of masoprocol on glucose transport and lipolysis by isolated rat adipocytes. Gowri, M.S., Reaven, G.M., Azhar, S. Metab. Clin. Exp. (1999)
- Masoprocol decreases serum triglyceride concentrations in rats with fructose-induced hypertriglyceridemia. Scribner, K.A., Gadbois, T.M., Gowri, M., Azhar, S., Reaven, G.M. Metab. Clin. Exp. (2000)
- Inhibition of 12- and 15-lipoxygenase activities and protection of human and tilapia low density lipoprotein oxidation by I-Tiao-Gung (Glycine tomentella). Chen, T.Y., Shiao, M.S., Pan, B.S. Lipids (2005)
- Inhibition of teleocidin-caused epidermal ornithine decarboxylase induction by phospholipase A2-, cyclooxygenase- and lipoxygenase-inhibitors. Nakadate, T., Aizu, E., Yamamoto, S., Fujiki, H., Sugimura, T., Kato, R. Jpn. J. Pharmacol. (1985)
- Regulation of the golgi structure by the alpha subunits of heterotrimeric G proteins. Yamaguchi, T., Nagahama, M., Itoh, H., Hatsuzawa, K., Tani, K., Tagaya, M. FEBS Lett. (2000)
- In vitro study of frog adrenal function--IX. Evidence against the involvement of lipoxygenase metabolites in the control of steroid production. Delarue, C., Lihrmann, I., Feuilloley, M., Netchitaïlo, P., Idres, S., Leboulenger, F., Bélanger, A., Perroteau, I., Vaudry, H. J. Steroid Biochem. (1988)
- Immunotherapy of warts with masoprocol cream. Epstein, E. Cutis; cutaneous medicine for the practitioner. (1997)