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Chemical Compound Review

PubChem12443     2-amino-4-sulfo-butanoic acid

Synonyms: ACMC-1AP11, ANW-30998, CHEBI:420562, KB-50321, LS-46100, ...
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Disease relevance of DL-Homocysteic acid


Psychiatry related information on DL-Homocysteic acid


High impact information on DL-Homocysteic acid


Chemical compound and disease context of DL-Homocysteic acid

  • Post-fixation treatment with homocysteic acid (HA) neutralizes this toxicity by bonding aldehyde groups, and enhances biocompatibility on the basis of strongly electronegative sulfonic groups [10].

Biological context of DL-Homocysteic acid


Anatomical context of DL-Homocysteic acid


Associations of DL-Homocysteic acid with other chemical compounds


Gene context of DL-Homocysteic acid


Analytical, diagnostic and therapeutic context of DL-Homocysteic acid


  1. Homocysteine increases cyclin-dependent kinase in aortic rat tissue. Lubec, B., Labudova, O., Hoeger, H., Muehl, A., Fang-Kircher, S., Marx, M., Mosgoeller, W., Gialamas, J. Circulation (1996) [Pubmed]
  2. Effect of pulmonary C-fibre afferent stimulation on cardiac vagal neurones in the nucleus ambiguus in anaesthetized cats. Wang, Y., Jones, J.F., Jeggo, R.D., de Burgh Daly, M., Jordan, D., Ramage, A.G. J. Physiol. (Lond.) (2000) [Pubmed]
  3. Effect of glutamate analogues on brain tumor cell lines. Campbell, G.L., Bartel, R., Freidman, H.S., Bigner, D.D. J. Neurochem. (1985) [Pubmed]
  4. Neurokinin-1 receptor-expressing cells regulate depressor region of rat ventrolateral medulla. Wang, H., Weston, M.C., McQuiston, T.J., Stornetta, R.L., Guyenet, P.G. Am. J. Physiol. Heart Circ. Physiol. (2003) [Pubmed]
  5. Dopaminergic neurotoxicity of homocysteine and its derivatives in primary mesencephalic cultures. Heider, I., Lehmensiek, V., Lenk, T., Müller, T., Storch, A. J. Neural Transm. Suppl. (2004) [Pubmed]
  6. Homocystinuria: pathogenetic mechanisms. Grieco, A.J. Am. J. Med. Sci. (1977) [Pubmed]
  7. Growth promotion by homocysteic acid. Clopath, P., Smith, V.C., McCully, K.S. Science (1976) [Pubmed]
  8. Effects of stimulation of the hypothalamic area on pancreatic exocrine secretion in dogs. Furukawa, N., Okada, H. Gastroenterology (1989) [Pubmed]
  9. Glutamate inhibits chondral mineralization through apoptotic cell death mediated by retrograde operation of the cystine/glutamate antiporter. Wang, L., Hinoi, E., Takemori, A., Nakamichi, N., Yoneda, Y. J. Biol. Chem. (2006) [Pubmed]
  10. Is the tricuspid position suitable for testing replacement bioprosthetic valves in the sheep model? Pettenazzo, E., Thiene, G., Gatti, A.M., Pasquino, E., Talenti, E., Noera, G., Bottio, T., Valente, M. J. Heart Valve Dis. (2001) [Pubmed]
  11. beta-Adrenergic stimulation promotes homocysteic acid release from astrocyte cultures: evidence for a role of astrocytes in the modulation of synaptic transmission. Do, K.Q., Benz, B., Sorg, O., Pellerin, L., Magistretti, P.J. J. Neurochem. (1997) [Pubmed]
  12. Inhibitory effects evoked from the rostral ventrolateral medulla are selective for the nociceptive responses of spinal dorsal horn neurons. Hudson, P.M., Semenenko, F.M., Lumb, B.M. Neuroscience (2000) [Pubmed]
  13. Viscerosomatic neurons in the lower thoracic spinal cord of the cat: excitations and inhibitions evoked by splanchnic and somatic nerve volleys and by stimulation of brain stem nuclei. Tattersall, J.E., Cervero, F., Lumb, B.M. J. Neurophysiol. (1986) [Pubmed]
  14. Blockade of delta opioid receptors in the ventrolateral periaqueductal gray region inhibits the fall in arterial pressure evoked by hemorrhage. Cavun, S., Resch, G.E., Evec, A.D., Rapacon-Baker, M.M., Millington, W.R. J. Pharmacol. Exp. Ther. (2001) [Pubmed]
  15. Neuronal cell death in hippocampus induced by homocysteic acid in immature rats. Langmeier, M., Folbergrová, J., Haugvicová, R., Pokorný, J., Mares, P. Epilepsia (2003) [Pubmed]
  16. Neurones in a discrete region of the nucleus tractus solitarius are required for the Breuer-Hering reflex in rat. Bonham, A.C., McCrimmon, D.R. J. Physiol. (Lond.) (1990) [Pubmed]
  17. Respiratory responses to electrical and chemical stimulation of the area postrema in the rabbit. Srinivasan, M., Bongianni, F., Fontana, G.A., Pantaleo, T. J. Physiol. (Lond.) (1993) [Pubmed]
  18. Synaptic mechanisms involved in the inspiratory modulation of vagal cardio-inhibitory neurones in the cat. Gilbey, M.P., Jordan, D., Richter, D.W., Spyer, K.M. J. Physiol. (Lond.) (1984) [Pubmed]
  19. Hypothalamic influences on viscero-somatic neurones in the lower thoracic spinal cord of the anaesthetized rat. Lumb, B.M. J. Physiol. (Lond.) (1990) [Pubmed]
  20. Mechanisms underlying recurrent inhibition in the sacral parasympathetic outflow to the urinary bladder. de Groat, W.C. J. Physiol. (Lond.) (1976) [Pubmed]
  21. Homocysteic acid as a putative excitatory amino acid neurotransmitter: I. Postsynaptic characteristics at N-methyl-D-aspartate-type receptors on striatal cholinergic interneurons. Lehmann, J., Tsai, C., Wood, P.L. J. Neurochem. (1988) [Pubmed]
  22. Increased cyclin dependent kinase in aortic tissue of rats fed homocysteine. Lubec, B., Arbeiter, K., Hoeger, H., Lubec, G. Thromb. Haemost. (1996) [Pubmed]
  23. Is excitation by enkephalins of hippocampal neurones in the rat due to presynaptic facilitation or to disinhibition? Haas, H.L., Ryall, R.W. J. Physiol. (Lond.) (1980) [Pubmed]
  24. The behavioural importance of dynamically activated descending inhibition from the nucleus reticularis gigantocellularis pars alpha. Azami, J., Green, D.L., Roberts, M.H., Monhemius, R. Pain (2001) [Pubmed]
  25. Methotrexate analogues. 32. Chain extension, alpha-carboxyl deletion, and gamma-carboxyl replacement by sulfonate and phosphonate: effect on enzyme binding and cell-growth inhibition. Rosowsky, A., Forsch, R.A., Moran, R.G., Kohler, W., Freisheim, J.H. J. Med. Chem. (1988) [Pubmed]
  26. Characterization of L-homocysteate-induced currents in Purkinje cells from wild-type and NMDA receptor knockout mice. Yuzaki, M., Connor, J.A. J. Neurophysiol. (1999) [Pubmed]
  27. Homocysteic acid: an examination of its possible growth hormone-like activity. Chrzanowska, B.L., Nitzan, M., Phillips, L.S., Schulman, J.D. Metab. Clin. Exp. (1979) [Pubmed]
  28. Lack of a direct effect of homocysteic acid on growth hormone and prolactin receptors. Bohnet, H.G. Endokrinologie. (1976) [Pubmed]
  29. Use of homocysteic acid for selecting mutants at the gltS locus of Escherichia coli K12. Essenberg, R.C. J. Gen. Microbiol. (1984) [Pubmed]
  30. Chemical activation of caudal medullary expiratory neurones alters the pattern of breathing in the cat. Bongianni, F., Corda, M., Fontana, G.A., Pantaleo, T. J. Physiol. (Lond.) (1994) [Pubmed]
  31. Taste responses of neurons in the hamster solitary nucleus are modulated by the central nucleus of the amygdala. Li, C.S., Cho, Y.K., Smith, D.V. J. Neurophysiol. (2002) [Pubmed]
  32. Identification and properties of sub-retrofacial bulbospinal neurones: a descending cardiovascular pathway in the cat. McAllen, R.M. J. Auton. Nerv. Syst. (1986) [Pubmed]
  33. Effect of central administration of phencyclidine on plasma concentrations of luteinizing hormone. Boggan, W.O., Ondo, J.G. Brain Res. (1989) [Pubmed]
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