The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

PubChem1301     1-pyridin-3-ylethanone

Synonyms: SureCN1699, NSC-761, AGN-PC-004C4M, NSC761, A21207_ALDRICH, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of beta-Acetylpyridine


Psychiatry related information on beta-Acetylpyridine

  • Animals were also trained on an unrotated rod or on a rod rotating at 5, 10 or 20 r.p.m. 3-Acetylpyridine-treated rats were able to maintain their equilibrium on the unrotated rod and at 5 r.p.m. Moreover, after motor training at 5 r.p.m., rats were able to improve their motor skills and reached the same score as controls [6].

High impact information on beta-Acetylpyridine


Chemical compound and disease context of beta-Acetylpyridine


Biological context of beta-Acetylpyridine


Anatomical context of beta-Acetylpyridine


Associations of beta-Acetylpyridine with other chemical compounds


Gene context of beta-Acetylpyridine


Analytical, diagnostic and therapeutic context of beta-Acetylpyridine


  1. HSV-mediated delivery of virally derived anti-apoptotic genes protects the rat hippocampus from damage following excitotoxicity, but not metabolic disruption. Roy, M., Hom, J.J., Sapolsky, R.M. Gene Ther. (2002) [Pubmed]
  2. Learning deficits on avoidance task and hippocampal lesions in area CA3 following intraperitoneal administration of 3-acetylpyridine. Ozaki, H.S., Murakami, T.H., Shimada, M. J. Neurosci. Res. (1983) [Pubmed]
  3. 3-Acetylpyridine-induced degeneration of the nigrostriatal dopamine system: an animal model of olivopontocerebellar atrophy-associated parkinsonism. Deutch, A.Y., Rosin, D.L., Goldstein, M., Roth, R.H. Exp. Neurol. (1989) [Pubmed]
  4. Insulin-like growth factor I modulates c-Fos induction and astrocytosis in response to neurotoxic insult. Fernandez, A.M., Garcia-Estrada, J., Garcia-Segura, L.M., Torres-Aleman, I. Neuroscience (1997) [Pubmed]
  5. Relationship of inferior olive-climbing fibers to p,p'-DDT-induced myoclonus in rats. Hwang, E.C., Plaitakis, A., Magnussen, I., Van Woert, M.H. Neurosci. Lett. (1981) [Pubmed]
  6. Role of the inferior olivary complex in motor skills and motor learning in the adult rat. Rondi-Reig, L., Delhaye-Bouchaud, N., Mariani, J., Caston, J. Neuroscience (1997) [Pubmed]
  7. Insulin-like growth factor I restores motor coordination in a rat model of cerebellar ataxia. Fernandez, A.M., de la Vega, A.G., Torres-Aleman, I. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  8. Adrenergic agents inhibit rapid increases in cerebellar Purkinje cell glutamic acid decarboxylase (GAD67) mRNA levels after climbing fiber lesions or reserpine treatment. Drengler, S.M., Lorden, J.F., Billitz, M.S., Oltmans, G.A. J. Neurosci. (1996) [Pubmed]
  9. Evidence for transsynaptic regulation of calmodulin-dependent cyclic nucleotide phosphodiesterase in cerebellar Purkinje cells. Balaban, C.D., Billingsley, M.L., Kincaid, R.L. J. Neurosci. (1989) [Pubmed]
  10. Calbindin D28K gene transfer via herpes simplex virus amplicon vector decreases hippocampal damage in vivo following neurotoxic insults. Phillips, R.G., Meier, T.J., Giuli, L.C., McLaughlin, J.R., Ho, D.Y., Sapolsky, R.M. J. Neurochem. (1999) [Pubmed]
  11. Niacinamide blocks 3-acetylpyridine toxicity of cerebellar granule cells in vitro. Weller, M., Marini, A.M., Paul, S.M. Brain Res. (1992) [Pubmed]
  12. Oxidative metabolism and acetylcholine synthesis during acetylpyridine treatment. Gibson, G.E., Blass, J.P. Neurochem. Res. (1985) [Pubmed]
  13. The effects of inferior olive lesion on strychnine seizure. Anderson, M.C., Chung, E.Y., Van Woert, M.H. Brain Res. Bull. (1990) [Pubmed]
  14. Endogenous estrogen formation is neuroprotective in model of cerebellar ataxia. Sierra, A., Azcoitia, I., Garcia-Segura, L. Endocrine (2003) [Pubmed]
  15. Effect of 3-acetylpyridine on the content of myelin in the developing rat brain. Nakashima, Y., Suzue, R. J. Nutr. Sci. Vitaminol. (1984) [Pubmed]
  16. Olivocerebellar projections modify hereditary Purkinje cell degeneration. Tolbert, D.L., Clark, B.R. Neuroscience (2000) [Pubmed]
  17. A herpes simplex virus vector overexpressing the glucose transporter gene protects the rat dentate gyrus from an antimetabolite toxin. Dash, R., Lawrence, M., Ho, D., Sapolsky, R. Exp. Neurol. (1996) [Pubmed]
  18. Granule neuron DNA damage following deafferentation in adult rats cerebellar cortex: a lesion model. Borsello, T., Di Luzio, A., Ciotti, M.T., Calissano, P., Galli, C. Neuroscience (2000) [Pubmed]
  19. Inferior olivary neurons: 3-acetylpyridine effects on glucose consumption, axonal transport, electrical activity and harmaline-induced tremor. Bernard, J.F., Buisseret-Delmas, C., Laplante, S. Brain Res. (1984) [Pubmed]
  20. Effect of 3-acetylpyridine on the development of rat brain. Nakashima, Y., Esashi, T. J. Nutr. Sci. Vitaminol. (1985) [Pubmed]
  21. Neuronal localization of specific angiotensin II binding sites in the rat inferior olivary nucleus. Walters, D.E., Speth, R.C. J. Neurochem. (1988) [Pubmed]
  22. Cerebellar output regulation by the climbing and mossy fibers with and without the inferior olive. Bardin, J.M., Batini, C., Billard, J.M., Buisseret-Delmas, C., Conrath-Verrier, M., Corvaja, N. J. Comp. Neurol. (1983) [Pubmed]
  23. Morphology of Purkinje cell axon terminals in intracerebellar nuclei following inferior olive lesion. Rossi, F., Cantino, D., Strata, P. Neuroscience (1987) [Pubmed]
  24. Neuroprotective actions of peripherally administered insulin-like growth factor I in the injured olivo-cerebellar pathway. Fernandez, A.M., Gonzalez de la Vega, A.G., Planas, B., Torres-Aleman, I. Eur. J. Neurosci. (1999) [Pubmed]
  25. Changes in the expression of the extracellular matrix molecules tenascin-C and tenascin-R after 3-acetylpyridine-induced lesion of the olivocerebellar system of the adult rat. Wintergerst, E.S., Bartsch, U., Batini, C., Schachner, M. Eur. J. Neurosci. (1997) [Pubmed]
  26. Neuroprotective effects of the dopamine agonists pramipexole and bromocriptine in 3-acetylpyridine-treated rats. Sethy, V.H., Wu, H., Oostveen, J.A., Hall, E.D. Brain Res. (1997) [Pubmed]
  27. Central neurotoxic effects of intraperitoneally administered 3-acetylpyridine, harmaline and niacinamide in Sprague-Dawley and Long-Evans rats: a critical review of central 3-acetylpyridine neurotoxicity. Balaban, C.D. Brain Res. (1985) [Pubmed]
  28. TRH receptor agonists ameliorate 3-acetylpyridine-induced ataxia through NMDA receptors in rats. Kinoshita, K., Watanabe, Y., Yamamura, M., Matsuoka, Y. Eur. J. Pharmacol. (1998) [Pubmed]
  29. Cerebellar nitric oxide synthase activity is reduced in nervous and Purkinje cell degeneration mutants but not in climbing fiber-lesioned mice. Ikeda, M., Morita, I., Murota, S., Sekiguchi, F., Yuasa, T., Miyatake, T. Neurosci. Lett. (1993) [Pubmed]
  30. Chemical lesion of the inferior olive reduces [125I]sarcosine1-angiotensin II binding to AT2 receptors in the cerebellar cortex of young rats. Jöhren, O., Häuser, W., Saavedra, J.M. Brain Res. (1998) [Pubmed]
  31. 28 K cholecalcin (CaBP) levels in abnormal cerebella: studies on mutant mice and harmaline- and 3-acetylpyridine-treated rats. Parkes, C.O., Mariani, J., Thomasset, M. Brain Res. (1985) [Pubmed]
  32. Maintenance of connexin 32 and 26 expression in primary cultured rat hepatocytes treated with 3-acetylpyridine. Higaki, N., Mitaka, T., Sato, F., Hirata, K., Mochizuki, Y. J. Gastroenterol. Hepatol. (2001) [Pubmed]
  33. Transitory disappearance of microglia during the regeneration of the lizard medial cortex. Lopez-Garcia, C., Nacher, J., Castellano, B., Luis de la Iglesia, J.A., Molowny, A. Glia (1994) [Pubmed]
  34. Immunocytochemical localization of tubulin and the high molecular weight microtubule-associated protein 2 in Purkinje cell dendrites deprived of climbing fibers. Caceres, A., Dotti, C. Neuroscience (1985) [Pubmed]
  35. 3-Acetylpyridine-induced degeneration in the dorsal root ganglia: involvement of small diameter neurons and influence of axotomy. Beiswanger, C.M., Roscoe-Graessle, T.L., Zerbe, N., Reuhl, K.R., Lowndes, H.E. Neuropathol. Appl. Neurobiol. (1993) [Pubmed]
  36. Reduction of GABAA and GABAB receptor densities in the cerebellar cortex from 3-acetylpyridine-induced ataxic rats. Kannari, K., Tomiyama, M., Matsunaga, M. Brain Res. (1994) [Pubmed]
  37. A new method for evaluation of motor deficits in 3-acetylpyridine-treated rats. Watanabe, Y., Kinoshita, K., Koguchi, A., Yamamura, M. J. Neurosci. Methods (1997) [Pubmed]
WikiGenes - Universities