Gene Review:
Serpine2 - serine (or cysteine) peptidase inhibitor,...
Mus musculus
Synonyms:
B230326M24Rik, GDN, Glia-derived nexin, PAI-1, PI-7, ...
- Protease nexin 1 in the murine kidney: glomerular localization and up-regulation in glomerulopathies. Moll, S., Schaeren-Wiemers, N., Wohlwend, A., Pastore, Y., Fulpius, T., Monard, D., Sappino, A.P., Schifferli, J.A., Vassalli, J.D., Izui, S. Kidney Int. (1996)
- Expression of trypsin-like proteases and protease nexin-1 in mdx mouse muscles. Sawada, H., Kikukawa, Y., Ban, S., Kakudo, T., Yokosawa, H. Biochem. Biophys. Res. Commun. (2004)
- Receptors for plasminogen activator, urokinase, in normal and Rous sarcoma virus-transformed mouse fibroblasts. Del Rosso, M., Dini, G., Fibbi, G. Cancer Res. (1985)
- Neurite outgrowth activity of protease nexin-1 on neuroblastoma cells requires thrombin inhibition. Gurwitz, D., Cunningham, D.D. J. Cell. Physiol. (1990)
- Male fertility defects in mice lacking the serine protease inhibitor protease nexin-1. Murer, V., Spetz, J.F., Hengst, U., Altrogge, L.M., de Agostini, A., Monard, D. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Cells regulate their mitogenic response to thrombin through release of protease nexin. Low, D.A., Scott, R.W., Baker, J.B., Cunningham, D.D. Nature (1982)
- Protease-nexin I as an androgen-dependent secretory product of the murine seminal vesicle. Vassalli, J.D., Huarte, J., Bosco, D., Sappino, A.P., Sappino, N., Velardi, A., Wohlwend, A., Ernø, H., Monard, D., Belin, D. EMBO J. (1993)
- Proteolytic action of thrombin is required for electrical activity-dependent synapse reduction. Liu, Y., Fields, R.D., Festoff, B.W., Nelson, P.G. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Sexually dimorphic expression of protease nexin-1 and vanin-1 in the developing mouse gonad prior to overt differentiation suggests a role in mammalian sexual development. Grimmond, S., Van Hateren, N., Siggers, P., Arkell, R., Larder, R., Soares, M.B., de Fatima Bonaldo, M., Smith, L., Tymowska-Lalanne, Z., Wells, C., Greenfield, A. Hum. Mol. Genet. (2000)
- Tissue-specific cancer-related serpin gene cluster at human chromosome band 3q26. Chang, W.S., Chang, N.T., Lin, S.C., Wu, C.W., Wu, F.Y. Genes Chromosomes Cancer (2000)
- Protease nexin-1 is expressed at the mouse met-/mesencephalic junction and FGF signaling regulates its promoter activity in primary met-/mesencephalic cells. Küry, P., Schaeren-Wiemers, N., Monard, D. Development (1997)
- Variable and multiple expression of Protease Nexin-1 during mouse organogenesis and nervous system development. Mansuy, I.M., van der Putten, H., Schmid, P., Meins, M., Botteri, F.M., Monard, D. Development (1993)
- Endogenous serine protease inhibitor modulates epileptic activity and hippocampal long-term potentiation. Lüthi, A., Van der Putten, H., Botteri, F.M., Mansuy, I.M., Meins, M., Frey, U., Sansig, G., Portet, C., Schmutz, M., Schröder, M., Nitsch, C., Laurent, J.P., Monard, D. J. Neurosci. (1997)
- Localization of protease nexin-1 gene Spi4 between villin and acetylcholine receptor gamma genes on mouse Chromosome 1. Voss, G.C., Botteri, F., Monard, D., Jockusch, H. Mamm. Genome (1996)
- Released protease-nexin regulates cellular binding, internalization, and degradation of serine proteases. Low, D.A., Baker, J.B., Koonce, W.C., Cunningham, D.D. Proc. Natl. Acad. Sci. U.S.A. (1981)
- Evidence that a variety of cultured cells secrete protease nexin and produce a distinct cytoplasmic serine protease-binding factor. Eaton, D.L., Baker, J.B. J. Cell. Physiol. (1983)
- Potential triple helix-mediated inhibition of IGF-I gene expression significantly reduces tumorigenicity of glioblastoma in an animal model. Shevelev, A., Burfeind, P., Schulze, E., Rininsland, F., Johnson, T.R., Trojan, J., Chernicky, C.L., Hélène, C., Ilan, J., Ilan, J. Cancer Gene Ther. (1997)
- A Krox binding site regulates protease nexin-1 promoter activity in embryonic heart, cartilage and parts of the nervous system. Ernø, H., Küry, P., Botteri, F.M., Monard, D. Mech. Dev. (1996)
- Protease nexin I, a serpin, inhibits plasminogen-dependent degradation of muscle extracellular matrix. Rao, J.S., Kahler, C.B., Baker, J.B., Festoff, B.W. Muscle Nerve (1989)
- Expression of mRNA for plasminogen activators and protease nexin-1 in innervated and denervated mouse skeletal muscle. Magnusson, C., Högklint, L., Libelius, R., Tågerud, S. J. Neurosci. Res. (2001)
- Regulation of prothrombin, thrombin receptor, and protease nexin-1 expression during development and after denervation in muscle. Kim, S., Buonanno, A., Nelson, P.G. J. Neurosci. Res. (1998)
- Two populations of layer v pyramidal cells of the mouse neocortex: development and sensitivity to anesthetics. Christophe, E., Doerflinger, N., Lavery, D.J., Molnár, Z., Charpak, S., Audinat, E. J. Neurophysiol. (2005)
- Apoptotic, injury-induced cell death in cultured mouse murine motor neurons. Citron, B.A., Zhang, S.X., Smirnova, I.V., Festoff, B.W. Neurosci. Lett. (1997)