Gene Review:
CBL - Cbl proto-oncogene, E3 ubiquitin protein...
Homo sapiens
Synonyms:
C-CBL, CBL2, Casitas B-lineage lymphoma proto-oncogene, E3 ubiquitin-protein ligase CBL, FRA11B, ...
- Identification of CBL, a proto-oncogene at 11q23.3, as a novel MLL fusion partner in a patient with de novo acute myeloid leukemia. Fu, J.F., Hsu, J.J., Tang, T.C., Shih, L.Y. Genes Chromosomes Cancer (2003)
- Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells. Sattler, M., Pride, Y.B., Quinnan, L.R., Verma, S., Malouf, N.A., Husson, H., Salgia, R., Lipkowitz, S., Griffin, J.D. Oncogene (2002)
- A novel dileucine lysosomal-sorting-signal mediates intracellular EGF-receptor retention independently of protein ubiquitylation. Tsacoumangos, A., Tsacoumango, A., Kil, S.J., Ma, L., Sönnichsen, F.D., Carlin, C. J. Cell. Sci. (2005)
- Formation of c-Cbl.phosphatidylinositol 3-kinase complexes on lymphocyte membranes by a p56lck-independent mechanism. Hartley, D., Corvera, S. J. Biol. Chem. (1996)
- Relationship of the human protooncogene CBL2 on 11q23 to the t(4;11), t(11;22), and t(11;14) breakpoints. Savage, P.D., Shapiro, M., Langdon, W.Y., Geurts van Kessel, A.D., Seuanez, H.N., Akao, Y., Croce, C., Morse, H.C., Kersey, J.H. Cytogenet. Cell Genet. (1991)
- Attitude towards computer-based learning: determinants as revealed by a controlled interventional study. Hahne, A.K., Benndorf, R., Frey, P., Herzig, S. Medical education. (2005)
- Association of a chromosome deletion syndrome with a fragile site within the proto-oncogene CBL2. Jones, C., Penny, L., Mattina, T., Yu, S., Baker, E., Voullaire, L., Langdon, W.Y., Sutherland, G.R., Richards, R.I., Tunnacliffe, A. Nature (1995)
- Cbl: many adaptations to regulate protein tyrosine kinases. Thien, C.B., Langdon, W.Y. Nat. Rev. Mol. Cell Biol. (2001)
- SHP-1 regulates Fcgamma receptor-mediated phagocytosis and the activation of RAC. Kant, A.M., De, P., Peng, X., Yi, T., Rawlings, D.J., Kim, J.S., Durden, D.L. Blood (2002)
- Cloning and characterization of a lymphoid-specific, inducible human protein tyrosine phosphatase, Lyp. Cohen, S., Dadi, H., Shaoul, E., Sharfe, N., Roifman, C.M. Blood (1999)
- Erythropoietin and interleukin-3 activate tyrosine phosphorylation of CBL and association with CRK adaptor proteins. Barber, D.L., Mason, J.M., Fukazawa, T., Reedquist, K.A., Druker, B.J., Band, H., D'Andrea, A.D. Blood (1997)
- Formalin-resistant leukocyte surface antigens in the diagnosis of cutaneous malignant lymphomas. Hauschild, A., Sterry, W. Am. J. Pathol. (1989)
- Acquired alkylating drug resistance of a human ovarian carcinoma cell line is unaffected by altered levels of pro- and anti-apoptotic proteins. Roy, G., Horton, J.K., Roy, R., Denning, T., Mitra, S., Boldogh, I. Oncogene (2000)
- Intrarenal octreotide treatment prevents sodium retention in liver cirrhotic rats: evidence for direct effects within the thick ascending limb of Henle's loop. Jonassen, T.E., Christensen, S., Marcussen, N., Petersen, J.S. Am. J. Physiol. Renal Physiol. (2006)
- Production and characterization of single chain Fv directed against beta2-agonist clenbuterol. Pan, K., Wang, H., Zhang, H.B., Liu, H.W., Lei, H.T., Huang, L., Sun, Y.M. J. Agric. Food Chem. (2006)
- The effect of an estrone D-lactam steroid ester derivative on breast cancer cells and its predicted binding interactions with the ligand binding domain of estrogen receptor-alpha. Kontos, M., Nikolopoulou, M., Trafalis, D.T., Geromichalos, G.D., Koukoulitsa, C., Camoutsis, J.C., Bastounis, E., Karamanakos, P. Oncol. Res. (2005)
- CBL-GRB2 interaction in myeloid immunoreceptor tyrosine activation motif signaling. Park, R.K., Kyono, W.T., Liu, Y., Durden, D.L. J. Immunol. (1998)
- All-trans-retinoic acid induces tyrosine phosphorylation of the CrkL adapter in acute promyelocytic leukemia cells. Alsayed, Y., Modi, S., Uddin, S., Mahmud, N., Druker, B.J., Fish, E.N., Hoffman, R., Platanias, L.C. Exp. Hematol. (2000)
- Interleukin 8 (IL-8) inhibits the interleukin 4 (IL-4)-induced but not the spontaneous growth of human B cells via mechanisms that may involve protein kinase C. Kimata, H., Fujimoto, M., Lindley, I., Furusho, K. Biochem. Biophys. Res. Commun. (1995)
- CD16-mediated activation of phosphatidylinositol-3 kinase (PI-3K) in human NK cells involves tyrosine phosphorylation of Cbl and its association with Grb2, Shc, pp36 and p85 PI-3K subunit. Cerboni, C., Gismondi, A., Palmieri, G., Piccoli, M., Frati, L., Santoni, A. Eur. J. Immunol. (1998)
- Protein tyrosine phosphatase inhibitors in Fc gamma RI-induced myeloid oxidant signaling. Erdreich-Epstein, A., Liu, M., Liu, Y., Durden, D.L. Exp. Cell Res. (1997)
- Effect of growth hormone and insulin-like growth factor-I on immunoglobulin production by and growth of human B cells. Kimata, H., Yoshida, A. J. Clin. Endocrinol. Metab. (1994)
- A gibberellin-regulated calcineurin B in rice localizes to the tonoplast and is implicated in vacuole function. Hwang, Y.S., Bethke, P.C., Cheong, Y.H., Chang, H.S., Zhu, T., Jones, R.L. Plant Physiol. (2005)
- The alloantigen-specific immunosuppressive activity of estradiol-chlorambucil conjugate (KM2210) and its beneficial effect on allogeneic bone marrow transplantation in mice. Matsudaira, T., Kodo, H., Okamoto, S., Tani, K., Tojo, A., Ozawa, K., Asano, K., Asano, S. Transplantation (1992)
- CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes. Reindl, C., Quentmeier, H., Petropoulos, K., Greif, P.A., Benthaus, T., Argiropoulos, B., Mellert, G., Vempati, S., Duyster, J., Buske, C., Bohlander, S.K., Humphries, K.R., Hiddemann, W., Spiekermann, K. Clin. Cancer Res. (2009)
- CSF-1 stimulation induces the formation of a multiprotein complex including CSF-1 receptor, c-Cbl, PI 3-kinase, Crk-II and Grb2. Husson, H., Mograbi, B., Schmid-Antomarchi, H., Fischer, S., Rossi, B. Oncogene (1997)
- Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL). Sattler, M., Salgia, R., Shrikhande, G., Verma, S., Pisick, E., Prasad, K.V., Griffin, J.D. J. Biol. Chem. (1997)
- Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH. Courbard, J.R., Fiore, F., Adélaïde, J., Borg, J.P., Birnbaum, D., Ollendorff, V. J. Biol. Chem. (2002)
- The CBL-related protein CBLB participates in FLT3 and interleukin-7 receptor signal transduction in pro-B cells. Lavagna-Sévenier, C., Marchetto, S., Birnbaum, D., Rosnet, O. J. Biol. Chem. (1998)
- CD38-mediated signaling events in murine pro-B cells expressing human CD38 with or without its cytoplasmic domain. Kitanaka, A., Suzuki, T., Ito, C., Nishigaki, H., Coustan-Smith, E., Tanaka, T., Kubota, Y., Campana, D. J. Immunol. (1999)
- Activation-dependent expression of the blood group-related lewis Y antigen on peripheral blood granulocytes. Dettke, M., Pálfi, G., Loibner, H. J. Leukoc. Biol. (2000)