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Chemical Compound Review

Fenilidrazina     phenylhydrazine

Synonyms: Phenyldiazane, Fenylhydrazine, Phenylhydrazin, SureCN7099, CCRIS 511, ...
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Disease relevance of phenylhydrazine


High impact information on phenylhydrazine


Chemical compound and disease context of phenylhydrazine


Biological context of phenylhydrazine


Anatomical context of phenylhydrazine


Associations of phenylhydrazine with other chemical compounds


Gene context of phenylhydrazine


Analytical, diagnostic and therapeutic context of phenylhydrazine

  • With phenylhydrazine concentrations below 30 mg/dL, even in the presence of multiple Heinz bodies, the RBC deformability measured by filtration through 2.6-, 4.5-, and 6.8-microns pores and the membrane deformability determined by a filter aspiration technique were not altered [23].
  • This lack of an ATP requirement means that the degradation of oxidant-damaged proteins does not require ligation to ubiquitin (even though phenylhydrazine treatment does make hemoglobin a very good substrate for ubiquitin conjugation) [34].
  • The oxidative metabolism of hydralazine, isoniazid, iproniazid, and phenylhydrazine has been studied using spin-trapping techniques [35].
  • UV-vis spectroscopic pH titration of phenylhydrazine adducts of 1(ox) and 4, 2, and 11, respectively, reveals a similar red shift in lambda(max) at alkaline pH with the same pK(a) (approximately 11.8) [36].
  • Splenectomy or injection of doses of phenylhydrazine-treated RBC which depressed splenic clearance function increased the susceptibility to septic peritonitis induced by cecal ligation and puncture [37].


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