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MeSH Review


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Disease relevance of Microsurgery


High impact information on Microsurgery


Chemical compound and disease context of Microsurgery


Biological context of Microsurgery


Anatomical context of Microsurgery

  • A comparison of glyceryl trinitrate and labetalol as hypotensive agents in microsurgery of the middle ear [21].
  • In embryos deprived of secondary mesenchyme cell (SMC) by microsurgery, the number of SRC decreased considerably [22].
  • Thus, the CO2 laser can significantly reduce postoperative adhesions in microsurgical uterine tube reanastomosis but without any significant histologic difference in tissue reunion, compared with conventional microsurgery [23].
  • Plasma membranes of such cells have been freshly prepared by freehand microsurgery and are tightly fixed over a 30-micrometers phi hole between two compartments of a microchamber containing 2.0 mM GABA in 7.5 microliters and 0.2 mM GABA in 75 microliters, respectively [24].
  • SETTING: Cell Biology Laboratory and the Laboratory for Intraocular Microsurgery and Implants, Goldschleger Eye Research Institute, Sackler School of Medicine, Tel-Aviv University, Chaim Sheba Medical Center, Tel-Hashomer, Israel. METHODS: In an in vitro study, cultured bovine corneal endothelial cells were exposed to diluted PI [25].

Associations of Microsurgery with chemical compounds

  • Ninety-five patients undergoing microsurgery of the middle ear were anaesthetised using thiopentone, nitrous oxide, oxygen and halothane via a low flow circle system, with carbon-dioxide absorption [21].
  • Additional studies will be required to determine if normalization of the circadian cortisol rhythm occurs in all patients with Cushing's disease who are cured after transsphenoidal microsurgery and who also show normal ACTH reserve [26].
  • We previously reported that vascularized bone allograft using immunosuppressants, such as cyclosporine A (CsA), is one approach for reconstruction of large bone defects in both experimental animals (Microsurgery 15:663; 1994) and clinically in humans (Lancet 347:970, 1996) [27].
  • METHODS: The concentration of putrescine, spermidine, and spermine, and the activity of ODC were biochemically quantified in tissue samples obtained during open microsurgery of 670 patients with brain tumours [28].
  • CO2 laser microsurgery differs from previous methods in that extremely fine and controlled therapy can be conducted with minimal damage to surrounding tissues and organs [29].

Gene context of Microsurgery

  • Our results suggest potential benefits via inhibition of iNOS to improve clinical outcomes not only for hand surgeons who work in the microsurgery field, but also for other physicians whose work involves ischemia/reperfusion injury [30].
  • In one out of two patients who had previously undergone unsuccessful pituitary microsurgery, neither basal nor oCRH-induced ACTH increases led to correct localization of the microadenoma within the pituitary [31].
  • CRH test after pituitary microsurgery suggests tertiary adrenocortical insufficiency in successful operated patients with Cushing's disease [32].
  • All 20 had bilateral proximal tubal obstruction without other tubal disease, and all had been recommended for tubal microsurgery or in vitro fertilization [33].
  • To characterize trophoblast cell-specific secretions, the inner cell mass was removed from all embryos by microsurgery on Day 13 [34].

Analytical, diagnostic and therapeutic context of Microsurgery


  1. Long term follow-up of women with surgically treated prolactin-secreting pituitary tumors. Schlechte, J.A., Sherman, B.M., Chapler, F.K., VanGilder, J. J. Clin. Endocrinol. Metab. (1986) [Pubmed]
  2. Cushing's syndrome. Schteingart, D.E. Endocrinol. Metab. Clin. North Am. (1989) [Pubmed]
  3. Primary microsurgery for postinflammatory tubal infertility. Jacobs, L.A., Thie, J., Patton, P.E., Williams, T.J. Fertil. Steril. (1988) [Pubmed]
  4. Simultaneous intrauterine twins and tubal pregnancy after conservative microsurgery for ectopic pregnancy in a patient with a single tube: case report. Oelsner, G., Morad, J., Ben-Rafael, Z., Mashiach, S. Fertil. Steril. (1985) [Pubmed]
  5. Transanal endoscopic microsurgery in large, sessile adenomas of the rectum. A 10-year experience. Said, S., Stippel, D. Surgical endoscopy. (1995) [Pubmed]
  6. Tests of prolactin secretion in diagnosis of prolactinomas. Cowden, E.A., Ratcliffe, J.G., Thomson, J.A., Macpherson, P., Doyle, D., Teasdale, G.M. Lancet (1979) [Pubmed]
  7. De novo formation of centrosomes in vertebrate cells arrested during S phase. Khodjakov, A., Rieder, C.L., Sluder, G., Cassels, G., Sibon, O., Wang, C.L. J. Cell Biol. (2002) [Pubmed]
  8. Feeding status and serotonin rapidly and reversibly modulate a Caenorhabditis elegans chemosensory circuit. Chao, M.Y., Komatsu, H., Fukuto, H.S., Dionne, H.M., Hart, A.C. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  9. Interferon alpha-2a therapy in 18 hemangioblastomas. Niemelä, M., Mäenpää, H., Salven, P., Summanen, P., Poussa, K., Laatikainen, L., Jääskeläinen, J., Joensuu, H. Clin. Cancer Res. (2001) [Pubmed]
  10. Improved diagnostic accuracy of inferior petrosal sinus sampling over imaging for localizing pituitary pathology in patients with Cushing's disease. Booth, G.L., Redelmeier, D.A., Grosman, H., Kovacs, K., Smyth, H.S., Ezzat, S. J. Clin. Endocrinol. Metab. (1998) [Pubmed]
  11. Absorption of lidocaine following topical application in microvascular procedures on rabbits. Hou, S.M., Liu, T.K., Yu, H.Y. J. Orthop. Res. (1991) [Pubmed]
  12. Combined (hormonal and microsurgical) therapy in infertile women with endometriosis. Donnez, J., Lemaire-Rubbers, M., Karaman, Y., Nisolle-Pochet, M., Casanas-Roux, F. Fertil. Steril. (1987) [Pubmed]
  13. Short-term preoperative treatment of macroprolactinomas by dopamine agonists. Fahlbusch, R., Buchfelder, M., Schrell, U. J. Neurosurg. (1987) [Pubmed]
  14. The proliferative potential of human pituitary tumors in situ. Nagashima, T., Murovic, J.A., Hoshino, T., Wilson, C.B., DeArmond, S.J. J. Neurosurg. (1986) [Pubmed]
  15. Assessment of definitive residual pituitary-adrenal function and of hydrocortisone replacement therapy 10 to 14 days after microsurgery for pituitary adenomas. Stracke, H., Schröder, O., Bleyl, H., Schatz, H. Horm. Metab. Res. (1984) [Pubmed]
  16. First and subsequent pregnancies after tubal microsurgery: evaluation of the fertility index. Gillett, W.R., Clarke, R.H., Herbison, G.P. Fertil. Steril. (1997) [Pubmed]
  17. Oocyte recovery, in vitro insemination, and transfer into the oviduct after its microsurgical repair at a single laparotomy. Tesarík, J., Pilka, L., Dvorák, M., Trávník, P. Fertil. Steril. (1983) [Pubmed]
  18. Tubal surgery and subsequent artificial insemination by donor. Lauritsen, J.G., Vangsted, P., Pagel, J.D., Starup, J. Acta obstetricia et gynecologica Scandinavica. (1983) [Pubmed]
  19. Glycine as an irrigant during microsurgical hemostasis. A microsurgeon's observations. Soderstrom, R.M. The Journal of reproductive medicine. (1991) [Pubmed]
  20. Carbon dioxide microsurgery in gynecology. Bellina, J.H. International advances in surgical oncology. (1978) [Pubmed]
  21. A comparison of glyceryl trinitrate and labetalol as hypotensive agents in microsurgery of the middle ear. Eltringham, R.J., Young, P.N., Littlejohns, P.A., Robinson, J.M. Eur. Heart J. (1988) [Pubmed]
  22. The 5-HT receptor cell is a new member of secondary mesenchyme cell descendants and forms a major blastocoelar network in sea urchin larvae. Katow, H., Yaguchi, S., Kiyomoto, M., Washio, M. Mech. Dev. (2004) [Pubmed]
  23. Clinical and histologic evaluation of laser reanastomosis of the uterine tube. Choe, J.K., Dawood, M.Y., Bardawil, W.A., Andrews, A.H. Fertil. Steril. (1984) [Pubmed]
  24. The effect of S100 protein on the plasma membrane function of neurons. Hydén, H., Lange, P.W. Cell. Mol. Neurobiol. (1981) [Pubmed]
  25. Corneal endothelial cytotoxicity of diluted povidone--iodine. Naor, J., Savion, N., Blumenthal, M., Assia, E.I. Journal of cataract and refractive surgery. (2001) [Pubmed]
  26. Circadian cortisol secretory rhythms in Cushing's disease. Boyar, R.M., Witkin, M., Carruth, A., Ramsey, J. J. Clin. Endocrinol. Metab. (1979) [Pubmed]
  27. Effects of vitamin D analog, 22-oxa-1,25-dihydroxyvitamin D(3), on bone reconstruction by vascularized bone allograft. Merida, L., Shigetomi, M., Ihara, K., Tsubone, T., Ikeda, K., Yamaguchi, A., Sugiyama, T., Kawai, S. Bone (2002) [Pubmed]
  28. Polyamine metabolism in brain tumours: diagnostic relevance of quantitative biochemistry. Ernestus, R.I., Röhn, G., Schröder, R., Els, T., Klekner A, n.u.l.l., Paschen, W., Klug, N. J. Neurol. Neurosurg. Psychiatr. (2001) [Pubmed]
  29. The CO2 laser as an ideal microsurgical tool. Ohshiro, T. Lasers in surgery and medicine. (1986) [Pubmed]
  30. Nitric oxide involvement in reperfusion injury of denervated muscle. Qi, W.N., Zhang, L., Chen, L.E., Seaber, A.V., Urbaniak, J.R. The Journal of hand surgery. (2004) [Pubmed]
  31. Bilateral and simultaneous venous sampling of inferior petrosal sinuses for ACTH and PRL determination: preoperative localization of ACTH-secreting microadenomas. Vignati, F., Berselli, M.E., Scialfa, G., Boccardi, E., Loli, P. J. Endocrinol. Invest. (1989) [Pubmed]
  32. CRH test after pituitary microsurgery suggests tertiary adrenocortical insufficiency in successful operated patients with Cushing's disease. Schrell, U., Fahlbusch, R., Buchfelder, M., Riedl, S., Stalla, G.K., Müller, O.A. Horm. Metab. Res. Suppl. (1987) [Pubmed]
  33. Nonsurgical fallopian tube recanalization for treatment of infertility. Thurmond, A.S., Rösch, J. Radiology. (1990) [Pubmed]
  34. Secretion of biologically active interferon tau by in vitro-derived bovine trophoblastic tissue. Stojkovic, M., Wolf, E., Büttner, M., Berg, U., Charpigny, G., Schmitt, A., Brem, G. Biol. Reprod. (1995) [Pubmed]
  35. Microsurgical salpingostomy is not an obsolete procedure. Winston, R.M., Margara, R.A. British journal of obstetrics and gynaecology. (1991) [Pubmed]
  36. Therapeutic strategies in tubal infertility with distal pathology. Audibert, F., Hédon, B., Arnal, F., Humeau, C., Boulot, P., Bachelard, B., Benos, P., Laffargue, F., Viala, J.L. Hum. Reprod. (1991) [Pubmed]
  37. The effect of treatment on experimentally produced endometrial peritoneal implants. Golan, A., Dargenio, R., Winston, R.M. Fertil. Steril. (1986) [Pubmed]
  38. Pregnancy following salpingostomy: comparison between CO2 laser and electrosurgery procedures. Mage, G., Bruhat, M.A. Fertil. Steril. (1983) [Pubmed]
  39. Laparoscopic microsurgical anastomosis of the blocked, solitary post-ectopic Fallopian tube: case report. Templeman, C., Davis, C., Janik, G., Koh, C. Hum. Reprod. (2002) [Pubmed]
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