Disease relevance of Rabbits

• OBJECTIVE: We recently implicated in vivo oxidative stress in the development of osteonecrosis in a steroid-induced osteonecrosis model in the domestic rabbit [1].
• The gene coding for phosphoglucomutase (PGM) from Oryctolagus cuniculus (rabbit) has been expressed in Escherichia coli under a T7 expression system with a His-tag [2].
• Pasteurella multocida infection in the domestic rabbit: immunization with a streptomycin-dependent mutant [3].
• The preventive effect of vitamin A acid (13-cis-retinoic acid) on skin papillomas induced in rabbits (Oryctolagus cuniculus) by the bite of bed bugs (Cimex lectularius) pre-irradiated with gamma rays was investigated [4].
• DESIGN: Silicone rubber endocasts from 14 adult New Zealand white rabbits (Oryctolagus cuniculus) with familial nonsyndromic coronal suture synostosis (five with bilateral coronal suture synostosis and nine with unilateral coronal suture synostosis) were made to assess middle meningeal vessel and dural venous sinus form [5].

Psychiatry related information on Rabbits

• In utero cocaine, discriminative avoidance learning with low-salient stimuli and learning-related neuronal activity in rabbits (Oryctolagus cuniculus) [6].

High impact information on Rabbits

• Male Wistar rats and male domestic rabbits received 14C- and/or 3H-labeled glucose intravenously, while the insulin preparations were administered by either the subcutaneous (s.c.) or the intravenous (i.v.) route [7].
• Known CD1 genes are grouped into the following three families, on the basis of evolutionary relationship: (1) the human HCD1B gene and a partial sequence from the domestic rabbit, (2) the human HCD1A and HCD1C genes, and (3) the human HCD1D and HCD1E genes plus the two mouse genes and a sequence from the cottontail rabbit [8].
• In addition, lithocholic acid was present as its sulfated amidate, whereas in the domestic rabbit, lithocholic acid was conjugated solely with glycine [9].
• In adult domestic rabbits, the dominant bile acid present was deoxycholic acid (88% of total bile acids), a secondary bile acid formed by the bacterial 7-dehydroxylation of cholic acid [9].
• The adult brush rabbit had a bile acid composition similar to that of the domestic rabbit, but about one-third of all bile acids were conjugated with taurine [9].

Biological context of Rabbits

• The cortex of the rabbit (Oryctolagus cuniculus) is rich in melatonin binding sites, and particularly abundant is the parietal cortex [10].
• Oestrous behaviour and circulating progesterone and oestrogen levels during pseudopregnancy in the domestic rabbit [11].
• The effect of dietary sucrose on lipid metabolism in Dutch belted rabbits (Oryctolagus cuniculus) [12].
• Phylogeography of the European rabbit (Oryctolagus cuniculus) in the Iberian Peninsula inferred from RFLP analysis of the cytochrome b gene [13].
• Effect of photoperiod and exogenous melatonin on correlates of estrus in the domestic rabbit [14].

Anatomical context of Rabbits

• Effect of photoperiod and melatonin on testis development and regression in wild European rabbits (Oryctolagus cuniculus) [15].
• The reproductive cycle of wild rabbits (Oryctolagus cuniculus) living in Zembra Island (North Tunisia) is dependent on an external factor, the photoperiod: the gonads are inhibited by long days and stimulated by short days or melatonin implants [16].
• In this study, vibrotactile stimulation of the mystacial vibrissae was examined as an alternative CS in the rabbit (Oryctolagus cuniculus) [17].
• Microscopic analysis of the temporomandibular joint in rabbits (Oryctolagus cuniculus L.) using an occlusal interference [18].
• Ramipril inhibition of rabbit (Oryctolagus cuniculus) small intestinal brush border membrane angiotensin converting enzyme [19].

Associations of Rabbits with chemical compounds

• In the present study, the medial septum was selectively lesioned with ibotenic acid in rabbits (Oryctolagus cuniculus), whose performance in a delay eyeblink conditioning paradigm was compared with that of intact controls. sham-operated controls, and intact controls given a systemic injection of scopolamine [20].
• The effect of dietary sucrose and hydrogenated coconut oil on atherosclerosis in Dutch belted rabbits (Oryctolagus cuniculus) [21].
• Relation between circulating sex steroid concentrations and sexual behaviour during pregnancy and post partum in the domestic rabbit [22].
• Two rabbit (Oryctolagus cuniculus) inbred strains (AX/JU and IIIVO/JU) have been used for genetic analysis of quantitative traits related to dietary cholesterol susceptibility [23].
• Seasonal changes in plasma testosterone, thyroxine, and cortisol levels in wild rabbits (Oryctolagus cuniculus algirus) of Zembra island [24].

Gene context of Rabbits

• All four sequences are related to the human CD1B and domestic rabbit CD1B-like sequences at both nucleotide and amino acid level [25].
• Genetic polymorphism of rabbit (Oryctolagus cuniculus) tissue acid phosphatases (ACP2 and ACP3) [26].
• In order to examine the gene regulation in rabbit pathophysiological models we attempted to clone full-length cDNAs encoding uPA and tPA from kidney extracts of rabbit (Oryctolagus cuniculus) by reverse transcription-polymerase chain reaction and rapid amplification of cDNA ends [27].
• Heterogeneity of Es-1 esterases in the rabbit (Oryctolagus cuniculus) [28].
• We have cloned and sequenced the p53-encoding rabbit cDNA (Oryctolagus cuniculus) [29].

Analytical, diagnostic and therapeutic context of Rabbits

• Four new alleles at the rabbit (Oryctolagus cuniculus) mannose-6-phosphate isomerase (E.C. 5.3.1.8, MPI) locus are proposed to account for phenotypes observed after starch gel electrophoresis and enzymatic staining of red cell lysates and tissues [30].
• Pharmacokinetics of tetracycline in the domestic rabbit following intravenous or oral administration [31].

References