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Chemical Compound Review

Cyclic AMP, 8-bromo     8-(6-amino-8-bromo-purin-9- yl)-3-hydroxy-3...

Synonyms: CHEMBL85519, AGN-PC-00IQQN, SureCN5951342, NSC-171719, AC1L1CIC, ...
 
 
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Disease relevance of Cyclic AMP, 8-bromo

 

High impact information on Cyclic AMP, 8-bromo

 

Chemical compound and disease context of Cyclic AMP, 8-bromo

 

Biological context of Cyclic AMP, 8-bromo

 

Anatomical context of Cyclic AMP, 8-bromo

  • We further show that VGF mRNA is induced in PC12 cells to a greater extent by depolarization and by phorbol-12-myristate-13-acetate treatment than by 8-bromo-cyclic AMP treatment [17].
  • Exposure of the normally non-fusing BeWo cells to 1.5 mM 8-bromo cyclic AMP induced cellular fusion and syncytium formation [18].
  • When veratrine-induced release of [3H]norepinephrine from cortex synaptosomes was examined, the facilitatory effects of forskolin, 8-bromo-cyclic AMP, and ZK 62771 were even more pronounced than in brain slices [19].
  • The PKA pathway seemed to inhibit both neoplastic and normal IFN-gamma-induced HLA-DR expression; addition of thyroid-stimulating hormone to normal thyroid cells, as well as 8-bromo cyclic AMP and forskolin to normal and neoplastic cells, reduced the amount of IFN-gamma-induced HLA-DR [20].
  • Regulation of low density lipoprotein receptor synthesis in cultured luteinized human granulosa cells by human chorionic gonadotropin and 8-bromo-cyclic AMP [21].
 

Associations of Cyclic AMP, 8-bromo with other chemical compounds

 

Gene context of Cyclic AMP, 8-bromo

 

Analytical, diagnostic and therapeutic context of Cyclic AMP, 8-bromo

References

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  18. E-cadherin expression during the differentiation of human trophoblasts. Coutifaris, C., Kao, L.C., Sehdev, H.M., Chin, U., Babalola, G.O., Blaschuk, O.W., Strauss, J.F. Development (1991) [Pubmed]
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  22. Cyclic AMP-modulated phosphorylation of intermediate filament proteins in cultured avian myogenic cells. Gard, D.L., Lazarides, E. Mol. Cell. Biol. (1982) [Pubmed]
  23. Evidence for the presence of cholesterol side chain cleavage cytochrome P-450 and adrenodoxin in fresh granulosa cells. Effects of follicle-stimulating hormone and cyclic AMP on cholesterol side chain cleavage cytochrome P-450 synthesis and activity. Funkenstein, B., Waterman, M.R., Masters, B.S., Simpson, E.R. J. Biol. Chem. (1983) [Pubmed]
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  30. Nitric oxide activates extracellular signal-regulated kinase 1/2 and enhances declustering of ionotropic glutamate receptor subunit 2/3 in rat cerebellar Purkinje cells. Endo, S., Launey, T. Neurosci. Lett. (2003) [Pubmed]
  31. Retinoic acid inhibits human thyroid peroxidase and thyroglobulin gene expression in cultured human thyrocytes. Namba, H., Yamashita, S., Morita, S., Villadolid, M.C., Kimura, H., Yokoyama, N., Izumi, M., Ishikawa, N., Ito, K., Nagataki, S. J. Endocrinol. Invest. (1993) [Pubmed]
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