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Chemical Compound Review

AC1MIWWM     disodium; molybdenum; oxygen(-2) anion

Synonyms: CCRIS 3927, 12680-49-8, 7631-95-0 (Parent), Molybdenum sodium oxide, disodium; molybdenum; oxygen(2-)
 
 
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Disease relevance of CCRIS 3927

 

High impact information on CCRIS 3927

 

Chemical compound and disease context of CCRIS 3927

 

Biological context of CCRIS 3927

 

Anatomical context of CCRIS 3927

 

Associations of CCRIS 3927 with other chemical compounds

 

Gene context of CCRIS 3927

  • With a modified assay (the presence of sodium molybdate and a reduction in the amount of charcoal used to adsorb "excess" ligand) we found that cytosol from LS180 cells contains a high concentration of AhR (400-500 fmol/mg cytosolic protein) when detected by [3H]TCDD or [3H]MC [28].
  • Routine addition of sodium molybdate to samples analyzed for PR by centrifugation overnight can be expected to yield an increased percent of receptor-positive patients with higher average concentration of receptor, compared with results of previous methodology [29].
  • The hormone-dependent interaction of vaults with estrogen receptor was reproducible in vitro and was prevented by sodium molybdate [30].
  • Expression of the human cDNA in a rabbit reticulocyte lysate system allowed functional analysis of ligand binding, agonist-induced and Ah receptor nuclear translocator-dependent DNA binding, and receptor stabilization by sodium molybdate [31].
  • After the inclusion of sodium molybdate in the reconstitution mixture, active sulfite oxidase was obtained, revealing that in vitro MPT synthase and aposulfite oxidase are sufficient for the insertion of MPT into sulfite oxidase and the conversion of MPT into Moco in the presence of high concentrations of molybdate [26].
 

Analytical, diagnostic and therapeutic context of CCRIS 3927

References

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  15. Effect of 17 beta-estradiol on the growth of estrogen receptor-positive human melanoma in vitro and in athymic mice. Feucht, K.A., Walker, M.J., Das Gupta, T.K., Beattie, C.W. Cancer Res. (1988) [Pubmed]
  16. Sulfate-reducing bacteria in floating macrophyte rhizospheres from an Amazonian floodplain lake in Bolivia and their association with Hg methylation. Achá, D., Iñiguez, V., Roulet, M., Guimarães, J.R., Luna, R., Alanoca, L., Sanchez, S. Appl. Environ. Microbiol. (2005) [Pubmed]
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  21. Action of glycerol and sodium molybdate in stabilization of the progesterone receptor from rat trophoblast. Ogle, T.F. J. Biol. Chem. (1983) [Pubmed]
  22. Glucocorticoid binding by human fetal membranes at term. López Bernal, A., Anderson, A.B., Demers, L.M., Turnbull, A.C. J. Clin. Endocrinol. Metab. (1982) [Pubmed]
  23. Use of chromatofocusing to distinguish estradiol receptor from ovarian-dependent and -independent rat mammary tumors. Coufalik, A.H., Feldman, M., Platica, M., Toth, L., Dreiling, D., Hollander, V.P. Cancer Res. (1983) [Pubmed]
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  30. Interaction of vault particles with estrogen receptor in the MCF-7 breast cancer cell. Abbondanza, C., Rossi, V., Roscigno, A., Gallo, L., Belsito, A., Piluso, G., Medici, N., Nigro, V., Molinari, A.M., Moncharmont, B., Puca, G.A. J. Cell Biol. (1998) [Pubmed]
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  32. Interaction of the Mr = 90,000 heat shock protein with the steroid-binding domain of the glucocorticoid receptor. Denis, M., Gustafsson, J.A., Wikström, A.C. J. Biol. Chem. (1988) [Pubmed]
  33. A new affinity resin for purification of non-transformed avian progesterone receptor. Grandics, P., Puri, R.K., Toft, D.O. Endocrinology (1982) [Pubmed]
  34. High-resolution separation of molybdate-stabilized progestin receptors using high-performance liquid chromatography. van der Walt, L.A., Wittliff, J.L. J. Chromatogr. (1988) [Pubmed]
  35. ATP-dependent activation of glucocorticoid-receptor complexes from the rat's heart. Kôrge, P. J. Steroid Biochem. (1984) [Pubmed]
 
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