Chemical Compound Review:
Alliosan 3-prop-2- enylsulfinylsulfanylprop-1- ene
Synonyms:
Allicin, Allimed, DADSO, CHEMBL359965, CPD-9275, ...
- Antimalarial activity of allicin, a biologically active compound from garlic cloves. Coppi, A., Cabinian, M., Mirelman, D., Sinnis, P. Antimicrob. Agents Chemother. (2006)
- Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis. Shadkchan, Y., Shemesh, E., Mirelman, D., Miron, T., Rabinkov, A., Wilchek, M., Osherov, N. J. Antimicrob. Chemother. (2004)
- Allicin in garlic protects against coronary endothelial dysfunction and right heart hypertrophy in pulmonary hypertensive rats. Sun, X., Ku, D.D. Am. J. Physiol. Heart Circ. Physiol. (2006)
- Allicin stimulates lymphocytes and elicits an antitumor effect: a possible role of p21ras. Patya, M., Zahalka, M.A., Vanichkin, A., Rabinkov, A., Miron, T., Mirelman, D., Wilchek, M., Lander, H.M., Novogrodsky, A. Int. Immunol. (2004)
- Pungent products from garlic activate the sensory ion channel TRPA1. Bautista, D.M., Movahed, P., Hinman, A., Axelsson, H.E., Sterner, O., Högestätt, E.D., Julius, D., Jordt, S.E., Zygmunt, P.M. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Selective expression of glutathione S-transferase genes in the murine gastrointestinal tract in response to dietary organosulfur compounds. Andorfer, J.H., Tchaikovskaya, T., Listowsky, I. Carcinogenesis (2004)
- The effects of allicin on weight in fructose-induced hyperinsulinemic, hyperlipidemic, hypertensive rats. Elkayam, A., Mirelman, D., Peleg, E., Wilchek, M., Miron, T., Rabinkov, A., Oron-Herman, M., Rosenthal, T. Am. J. Hypertens. (2003)
- Induction of total insensitivity to capsaicin and hypersensitivity to garlic extract in human by decreased expression of TRPV1. Park, J.J., Lee, J., Kim, M.A., Back, S.K., Hong, S.K., Na, H.S. Neurosci. Lett. (2007)
- Inhibition of GSH-dependent PGH2 isomerase in mammary adenocarcinoma cells by allicin. Shalinsky, D.R., McNamara, D.B., Agrawal, K.C. Prostaglandins (1989)
- Caspase-independent cell death by allicin in human epithelial carcinoma cells: involvement of PKA. Park, S.Y., Cho, S.J., Kwon, H.C., Lee, K.R., Rhee, D.K., Pyo, S. Cancer Lett. (2005)
- In vitro mechanism of inhibition of bacterial cell growth by allicin. Feldberg, R.S., Chang, S.C., Kotik, A.N., Nadler, M., Neuwirth, Z., Sundstrom, D.C., Thompson, N.H. Antimicrob. Agents Chemother. (1988)
- Allicin from garlic strongly inhibits cysteine proteinases and cytopathic effects of Entamoeba histolytica. Ankri, S., Miron, T., Rabinkov, A., Wilchek, M., Mirelman, D. Antimicrob. Agents Chemother. (1997)
- Ajoene, the antiplatelet compound derived from garlic, specifically inhibits platelet release reaction by affecting the plasma membrane internal microviscosity. Rendu, F., Daveloose, D., Debouzy, J.C., Bourdeau, N., Levy-Toledano, S., Jain, M.K., Apitz-Castro, R. Biochem. Pharmacol. (1989)
- Suppression of Mycobacterium tuberculosis induced reactive oxygen species (ROS) and TNF-alpha mRNA expression in human monocytes by allicin. Hasan, N., Yusuf, N., Toossi, Z., Islam, N. FEBS Lett. (2006)
- Effect of allicin and ajoene, two compounds of garlic, on inducible nitric oxide synthase. Dirsch, V.M., Kiemer, A.K., Wagner, H., Vollmar, A.M. Atherosclerosis (1998)
- Allicin, a naturally occurring antibiotic from garlic, specifically inhibits acetyl-CoA synthetase. Focke, M., Feld, A., Lichtenthaler, K. FEBS Lett. (1990)
- Determination of allicin, S-allylcysteine and volatile metabolites of garlic in breath, plasma or simulated gastric fluids. Rosen, R.T., Hiserodt, R.D., Fukuda, E.K., Ruiz, R.J., Zhou, Z., Lech, J., Rosen, S.L., Hartman, T.G. J. Nutr. (2001)
- Allicin release under simulated gastrointestinal conditions from garlic powder tablets employed in clinical trials on serum cholesterol. Lawson, L.D., Wang, Z.J., Papadimitriou, D. Planta Med. (2001)
- Enhancement of the Fungicidal Activity of Amphotericin B by Allicin, an Allyl-Sulfur Compound from Garlic, against the Yeast Saccharomyces cerevisiae as a Model System. Ogita, A., Fujita, K., Taniguchi, M., Tanaka, T. Planta Med. (2006)
- Characterization of the formation of allicin and other thiosulfinates from garlic. Lawson, L.D., Hughes, B.G. Planta Med. (1992)
- Allylmercaptocaptopril: a new antihypertensive drug. Miron, T., Rabinkov, A., Peleg, E., Rosenthal, T., Mirelman, D., Wilchek, M. Am. J. Hypertens. (2004)
- Metabolism of diallyl disulfide by human liver microsomal cytochromes P-450 and flavin-containing monooxygenases. Teyssier, C., Guenot, L., Suschetet, M., Siess, M.H. Drug Metab. Dispos. (1999)
- Allicin inhibits SDF-1alpha-induced T cell interactions with fibronectin and endothelial cells by down-regulating cytoskeleton rearrangement, Pyk-2 phosphorylation and VLA-4 expression. Sela, U., Ganor, S., Hecht, I., Brill, A., Miron, T., Rabinkov, A., Wilchek, M., Mirelman, D., Lider, O., Hershkoviz, R. Immunology (2004)
- Allicin characterization and its determination by HPLC. Jansen, H., Müller, B., Knobloch, K. Planta Med. (1987)
- Quantitative determination of allicin in garlic: supercritical fluid extraction and standard addition of alliin. Rybak, M.E., Calvey, E.M., Harnly, J.M. J. Agric. Food Chem. (2004)
- Hypocholesterolemic effect of an enteric-coated garlic supplement. Kannar, D., Wattanapenpaiboon, N., Savige, G.S., Wahlqvist, M.L. Journal of the American College of Nutrition. (2001)