The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

BIPHENYLENE     biphenylene

Synonyms: Diphenylene, PubChem9106, CHEBI:33079, ANW-58468, NSC-101862, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of biphenylene


High impact information on biphenylene


Chemical compound and disease context of biphenylene


Biological context of biphenylene


Anatomical context of biphenylene


Associations of biphenylene with other chemical compounds


Gene context of biphenylene


Analytical, diagnostic and therapeutic context of biphenylene


  1. Differential inhibition by iodonium compounds of induced erythropoietin expression. Goldwasser, E., Alibali, P., Gardner, A. J. Biol. Chem. (1995) [Pubmed]
  2. Lysophosphatidic acid stimulates p21-activated kinase in vascular smooth muscle cells. Schmitz, U., Thömmes, K., Beier, I., Vetter, H. Biochem. Biophys. Res. Commun. (2002) [Pubmed]
  3. Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts. Nakahira, K., Kim, H.P., Geng, X.H., Nakao, A., Wang, X., Murase, N., Drain, P.F., Wang, X., Sasidhar, M., Nabel, E.G., Takahashi, T., Lukacs, N.W., Ryter, S.W., Morita, K., Choi, A.M. J. Exp. Med. (2006) [Pubmed]
  4. Simultaneous activation of NADPH oxidase-related proton and electron currents in human neutrophils. DeCoursey, T.E., Cherny, V.V., Zhou, W., Thomas, L.L. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  5. Elicitor-stimulated ion fluxes and O2- from the oxidative burst are essential components in triggering defense gene activation and phytoalexin synthesis in parsley. Jabs, T., Tschope, M., Colling, C., Hahlbrock, K., Scheel, D. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  6. Redox changes of cultured endothelial cells and actin dynamics. Moldovan, L., Moldovan, N.I., Sohn, R.H., Parikh, S.A., Goldschmidt-Clermont, P.J. Circ. Res. (2000) [Pubmed]
  7. A role for reactive oxygen species in endothelial cell anoikis. Li, A.E., Ito, H., Rovira, I.I., Kim, K.S., Takeda, K., Yu, Z.Y., Ferrans, V.J., Finkel, T. Circ. Res. (1999) [Pubmed]
  8. Acute hypoxia simultaneously induces the expression of gp91phox and endothelial nitric oxide synthase in the porcine pulmonary artery. Muzaffar, S., Shukla, N., Angelini, G.D., Jeremy, J.Y. Thorax (2005) [Pubmed]
  9. Mitogen activated protein kinase (MAPK) pathway regulates heme oxygenase-1 gene expression by hypoxia in vascular cells. Ryter, S.W., Xi, S., Hartsfield, C.L., Choi, A.M. Antioxid. Redox Signal. (2002) [Pubmed]
  10. Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells. Rocic, P., Seshiah, P., Griendling, K.K. J. Biol. Chem. (2003) [Pubmed]
  11. Tumor necrosis factor-alpha increases airway smooth muscle oxidants production through a NADPH oxidase-like system to enhance myosin light chain phosphorylation and contractility. Thabut, G., El-Benna, J., Samb, A., Corda, S., Megret, J., Leseche, G., Vicaut, E., Aubier, M., Boczkowski, J. J. Biol. Chem. (2002) [Pubmed]
  12. Characterization of mitochondrial and extra-mitochondrial oxygen consuming reactions in human hematopoietic stem cells. Novel evidence of the occurrence of NAD(P)H oxidase activity. Piccoli, C., Ria, R., Scrima, R., Cela, O., D'Aprile, A., Boffoli, D., Falzetti, F., Tabilio, A., Capitanio, N. J. Biol. Chem. (2005) [Pubmed]
  13. Peroxidase-dependent apoplastic oxidative burst in Arabidopsis required for pathogen resistance. Bindschedler, L.V., Dewdney, J., Blee, K.A., Stone, J.M., Asai, T., Plotnikov, J., Denoux, C., Hayes, T., Gerrish, C., Davies, D.R., Ausubel, F.M., Paul Bolwell, G. Plant J. (2006) [Pubmed]
  14. A hepatitis C virus-encoded, nonstructural protein (NS3) triggers dysfunction and apoptosis in lymphocytes: role of NADPH oxidase-derived oxygen radicals. Thorén, F., Romero, A., Lindh, M., Dahlgren, C., Hellstrand, K. J. Leukoc. Biol. (2004) [Pubmed]
  15. Functional expression of NADPH oxidase components (alpha- and beta-subunits of cytochrome b558 and 45-kDa flavoprotein) by intrinsic human glomerular mesangial cells. Radeke, H.H., Cross, A.R., Hancock, J.T., Jones, O.T., Nakamura, M., Kaever, V., Resch, K. J. Biol. Chem. (1991) [Pubmed]
  16. Oxidative stress in scleroderma: maintenance of scleroderma fibroblast phenotype by the constitutive up-regulation of reactive oxygen species generation through the NADPH oxidase complex pathway. Sambo, P., Baroni, S.S., Luchetti, M., Paroncini, P., Dusi, S., Orlandini, G., Gabrielli, A. Arthritis Rheum. (2001) [Pubmed]
  17. Microglia proliferation is regulated by hydrogen peroxide from NADPH oxidase. Mander, P.K., Jekabsone, A., Brown, G.C. J. Immunol. (2006) [Pubmed]
  18. Reactive oxygen species mediate virus-induced STAT activation: role of tyrosine phosphatases. Liu, T., Castro, S., Brasier, A.R., Jamaluddin, M., Garofalo, R.P., Casola, A. J. Biol. Chem. (2004) [Pubmed]
  19. Cis-unsaturated Fatty acids stimulate reactive oxygen species generation and lipid peroxidation in human spermatozoa. Aitken, R.J., Wingate, J.K., De Iuliis, G.N., Koppers, A.J., McLaughlin, E.A. J. Clin. Endocrinol. Metab. (2006) [Pubmed]
  20. Angiotensin II activates Akt/protein kinase B by an arachidonic acid/redox-dependent pathway and independent of phosphoinositide 3-kinase. Gorin, Y., Kim, N.H., Feliers, D., Bhandari, B., Choudhury, G.G., Abboud, H.E. FASEB J. (2001) [Pubmed]
  21. Roles of tyrosine kinases in the regulation of nitric oxide synthesis in murine liver cells: modulation of NF-kappa B activity by tyrosine kinases. Lee, B.S., Kang, H.S., Pyun, K.H., Choi, I. Hepatology (1997) [Pubmed]
  22. Reactive oxygen species mediate the activation of Akt/protein kinase B by angiotensin II in vascular smooth muscle cells. Ushio-Fukai, M., Alexander, R.W., Akers, M., Yin, Q., Fujio, Y., Walsh, K., Griendling, K.K. J. Biol. Chem. (1999) [Pubmed]
  23. Characterization of a Rac1 signaling pathway to cyclin D(1) expression in airway smooth muscle cells. Page, K., Li, J., Hodge, J.A., Liu, P.T., Vanden Hoek, T.L., Becker, L.B., Pestell, R.G., Rosner, M.R., Hershenson, M.B. J. Biol. Chem. (1999) [Pubmed]
  24. Hydrogen peroxide-mediated transcriptional induction of macrophage colony-stimulating factor by TGF-beta1. Hong, Y.H., Peng, H.B., La Fata, V., Liao, J.K. J. Immunol. (1997) [Pubmed]
  25. Convergence of redox-sensitive and mitogen-activated protein kinase signaling pathways in tumor necrosis factor-alpha-mediated monocyte chemoattractant protein-1 induction in vascular smooth muscle cells. De Keulenaer, G.W., Ushio-Fukai, M., Yin, Q., Chung, A.B., Lyons, P.R., Ishizaka, N., Rengarajan, K., Taylor, W.R., Alexander, R.W., Griendling, K.K. Arterioscler. Thromb. Vasc. Biol. (2000) [Pubmed]
  26. A constitutive NADPH oxidase-like system containing gp91phox homologs in human keratinocytes. Chamulitrat, W., Stremmel, W., Kawahara, T., Rokutan, K., Fujii, H., Wingler, K., Schmidt, H.H., Schmidt, R. J. Invest. Dermatol. (2004) [Pubmed]
  27. An oxidative stress-mediated death pathway in irradiated human leukemia cells mapped using multilaser flow cytometry. Sheng-Tanner, X., Bump, E.A., Hedley, D.W. Radiat. Res. (1998) [Pubmed]
  28. Endothelin-1 and smooth muscle cells: induction of jun amino-terminal kinase through an oxygen radical-sensitive mechanism. Fei, J., Viedt, C., Soto, U., Elsing, C., Jahn, L., Kreuzer, J. Arterioscler. Thromb. Vasc. Biol. (2000) [Pubmed]
  29. Superoxide, H2O2, and iron are required for TNF-alpha-induced MCP-1 gene expression in endothelial cells: role of Rac1 and NADPH oxidase. Chen, X.L., Zhang, Q., Zhao, R., Medford, R.M. Am. J. Physiol. Heart Circ. Physiol. (2004) [Pubmed]
  30. NADPH oxidase does not account fully for O2-sensing in model airway chemoreceptor cells. O'Kelly, I., Peers, C., Kemp, P.J. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
WikiGenes - Universities