Gene Review:
Adcyap1r1 - adenylate cyclase activating polypeptide 1...
Mus musculus
Synonyms:
2900024I10Rik, AI846590, PAC1, PAC1R, PACAP type I receptor, ...
- Anti-inflammatory role in septic shock of pituitary adenylate cyclase-activating polypeptide receptor. Martinez, C., Abad, C., Delgado, M., Arranz, A., Juarranz, M.G., Rodriguez-Henche, N., Brabet, P., Leceta, J., Gomariz, R.P. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Analysis of the role of the PAC1 receptor in neutrophil recruitment, acute-phase response, and nitric oxide production in septic shock. Martínez, C., Juarranz, Y., Abad, C., Arranz, A., Miguel, B.G., Rosignoli, F., Leceta, J., Gomariz, R.P. J. Leukoc. Biol. (2005)
- Impaired long-term potentiation in vivo in the dentate gyrus of pituitary adenylate cyclase-activating polypeptide (PACAP) or PACAP type 1 receptor-mutant mice. Matsuyama, S., Matsumoto, A., Hashimoto, H., Shintani, N., Baba, A. Neuroreport (2003)
- A vasoactive intestinal peptide antagonist inhibits the growth of glioblastoma cells. Sharma, A., Walters, J., Gozes, Y., Fridkin, M., Brenneman, D., Gozes, I., Moody, T.W. J. Mol. Neurosci. (2001)
- Pulmonary hypertension and right heart failure in pituitary adenylate cyclase-activating polypeptide type I receptor-deficient mice. Otto, C., Hein, L., Brede, M., Jahns, R., Engelhardt, S., Gröne, H.J., Schütz, G. Circulation (2004)
- Altered emotional behavior in PACAP-type-I-receptor-deficient mice. Otto, C., Martin, M., Wolfer, D.P., Lipp, H.P., Maldonado, R., Schütz, G. Brain Res. Mol. Brain Res. (2001)
- Altered social behavior in pituitary adenylate cyclase-activating polypeptide type I receptor-deficient mice. Nicot, A., Otto, T., Brabet, P., Dicicco-Bloom, E.M. J. Neurosci. (2004)
- PAC1 receptor-deficient mice display impaired insulinotropic response to glucose and reduced glucose tolerance. Jamen, F., Persson, K., Bertrand, G., Rodriguez-Henche, N., Puech, R., Bockaert, J., Ahrén, B., Brabet, P. J. Clin. Invest. (2000)
- Neural tube expression of pituitary adenylate cyclase-activating peptide (PACAP) and receptor: potential role in patterning and neurogenesis. Waschek, J.A., Casillas, R.A., Nguyen, T.B., DiCicco-Bloom, E.M., Carpenter, E.M., Rodriguez, W.I. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Differential requirements for calcium and Src family kinases in platelet GPIIb/IIIa activation and thromboxane generation downstream of different G-protein pathways. Dorsam, R.T., Kim, S., Murugappan, S., Rachoor, S., Shankar, H., Jin, J., Kunapuli, S.P. Blood (2005)
- Induction of fibrinogen binding and platelet aggregation as a potential intrinsic property of various glycoprotein IIb/IIIa (alphaIIbbeta3) inhibitors. Peter, K., Schwarz, M., Ylänne, J., Kohler, B., Moser, M., Nordt, T., Salbach, P., Kübler, W., Bode, C. Blood (1998)
- Activation of the mitogen-activated protein kinase pathway induces transcription of the PAC-1 phosphatase gene. Grumont, R.J., Rasko, J.E., Strasser, A., Gerondakis, S. Mol. Cell. Biol. (1996)
- Ectopic alphaIIbbeta3 integrin signaling involves 12-lipoxygenase- and PKC-mediated serine phosphorylation events in melanoma cells. Rásó, E., Tóvári, J., Tóth, K., Paku, S., Trikha, M., Honn, K.V., Tímár, J. Thromb. Haemost. (2001)
- Ligand-mimetic anti-alphaIIb beta3 antibody PAC-1 inhibits tyrosine signaling, proliferation and lung colonization of melanoma cells. Rásó, E., Tóvári, J., Ladányi, A., Varga, N., Tímár, J. Pathol. Oncol. Res. (2005)
- Expression of PACAP, and PACAP type 1 (PAC1) receptor mRNA during development of the mouse embryo. Sheward, W.J., Lutz, E.M., Copp, A.J., Harmar, A.J. Brain Res. Dev. Brain Res. (1998)
- Up-regulation of the PACAP type-1 receptor (PAC1) promoter by neurotrophins in rat PC12 cells and mouse cerebellar granule cells via the Ras/mitogen-activated protein kinase cascade. Jamen, F., Bouschet, T., Laden, J.C., Bockaert, J., Brabet, P. J. Neurochem. (2002)
- Structure of the gene encoding the mouse pituitary adenylate cyclase-activating polypeptide receptor. Aino, H., Hashimoto, H., Ogawa, N., Nishino, A., Yamamoto, K., Nogi, H., Nagata, S., Baba, A. Gene (1995)
- VIP and PACAP induce selective neuronal differentiation of mouse embryonic stem cells. Cazillis, M., Gonzalez, B.J., Billardon, C., Lombet, A., Fraichard, A., Samarut, J., Gressens, P., Vaudry, H., Rostène, W. Eur. J. Neurosci. (2004)
- Embryonic expression of pituitary adenylyl cyclase-activating polypeptide and its selective type I receptor gene in the frog Xenopus laevis neural tube. Hu, Z., Lelievre, V., Rodriguez, W.I., Tam, J., Cheng, J.W., Cohen-Cory, S., Waschek, J.A. J. Comp. Neurol. (2001)
- Pituitary adenylate cyclase-activating polypeptide promotes differentiation of mouse neural stem cells into astrocytes. Ohno, F., Watanabe, J., Sekihara, H., Hirabayashi, T., Arata, S., Kikuyama, S., Shioda, S., Nakaya, K., Nakajo, S. Regul. Pept. (2005)
- Pituitary adenylate cyclase activating polypeptide-mediated intracrine signaling in the testicular germ cells. Li, M., Funahashi, H., Mbikay, M., Shioda, S., Arimura, A. Endocrine (2004)
- Markedly reduced chronic nociceptive response in mice lacking the PAC1 receptor. Jongsma, H., Pettersson, L.M., Zhang Yz, n.u.l.l., Reimer, M.K., Kanje, M., Waldenström, A., Sundler, F., Danielsen, N. Neuroreport (2001)
- Differential expression of glutamate transporters EAAT1 and EAAT2 in mice deficient for PACAP-type I receptor. Zink, M., Schmitt, A., Henn, F.A., Gass, P. Journal of neural transmission (Vienna, Austria : 1996) (2004)
- Mutation of a ligand binding domain of beta 3 integrin. Integral role of oxygenated residues in alpha IIb beta 3 (GPIIb-IIIa) receptor function. Bajt, M.L., Loftus, J.C. J. Biol. Chem. (1994)
- Reduced expression of brain-derived neurotrophic factor in mice deficient for pituitary adenylate cyclase activating polypeptide type-I-receptor. Zink, M., Otto, C., Zörner, B., Zacher, C., Schütz, G., Henn, F.A., Gass, P. Neurosci. Lett. (2004)
- The neuropeptide PACAP contributes to the glucagon response to insulin-induced hypoglycaemia in mice. Persson, K., Ahrén, B. Acta Physiol. Scand. (2002)
- Dissociation between light-induced phase shift of the circadian rhythm and clock gene expression in mice lacking the pituitary adenylate cyclase activating polypeptide type 1 receptor. Hannibal, J., Jamen, F., Nielsen, H.S., Journot, L., Brabet, P., Fahrenkrug, J. J. Neurosci. (2001)
- Altered calmodulin response to light in the suprachiasmatic nucleus of PAC1 receptor knockout mice revealed by proteomic analysis. Fahrenkrug, J., Hannibal, J., Honoré, B., Vorum, H. J. Mol. Neurosci. (2005)