The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Neural Pathways

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Neural Pathways


Psychiatry related information on Neural Pathways


High impact information on Neural Pathways


Chemical compound and disease context of Neural Pathways


Biological context of Neural Pathways


Anatomical context of Neural Pathways


Associations of Neural Pathways with chemical compounds

  • To provide a link between the clock and the sun compass, we identified a CRYPTOCHROME-staining neural pathway that likely connects the circadian clock to polarized light input entering brain [30].
  • Pancreatic responses to intraduodenal administration of maltose, hyperosmolar NaCl, and light mucosal stroking were examined in rats pretreated with various pharmacological antagonists or after surgical or chemical ablation of vagal and 5-HT neural pathways [31].
  • CONCLUSIONS: These results indicate that intragastric capsaicin predominantly stimulates motility in the proximal half of the colon through neural pathways, probably through a vagovagal reflex, but sympathetic involvement cannot be excluded [32].
  • This effect is reversed by hexamethonium, suggesting that a neural pathway is involved [33].
  • To determine the nature of the neural pathways mediating the bombesin-induced somatostatin release, atropine (100 nmol/L) was used [34].

Gene context of Neural Pathways

  • The excitatory effect is also dependent on sensory neural pathways and requires both NK1 and NK2 receptors [35].
  • In conclusion, we have found that the proinflammatory cytokine IL-1beta specifically activates certain neurochemically defined neural pathways and that these changes may lead to disturbances in motility observed in the inflamed bowel [36].
  • Furthermore, the data support the notion that rolipram, the PDE4-specific inhibitor that acts as an antidepressant in humans, may mediate its behavioral effects through PDE4B, which is highly localized to neural pathways known to underlie reward and affect in mammals [37].
  • Recent studies in female mice that cannot synthesize oxytocin (OT) suggest that central OT neural pathways attenuate the response of the hypothalamic-pituitary-adrenal (HPA) axis to certain stressors [38].
  • It appears therefore that, as expected, NPY and alpha-MSH closely interact in the control of feeding, whereas the neural pathways by which NPY affects growth and reproduction are distinct and not sensitive to MC peptide modulation [39].

Analytical, diagnostic and therapeutic context of Neural Pathways


  1. A cholinergic link in the reflex release of vasopressin by hypotension in the rat. Bisset, G.W., Chowdrey, H.S. J. Physiol. (Lond.) (1984) [Pubmed]
  2. Colocalization of nitric oxide synthase and some neurotransmitters in the intramural ganglia of the guinea pig urinary bladder. Zhou, Y., Ling, E.A. J. Comp. Neurol. (1998) [Pubmed]
  3. Selective lesions of neural pathways following viral inoculation of the olfactory bulb. McLean, J.H., Shipley, M.T., Bernstein, D.I., Corbett, D. Exp. Neurol. (1993) [Pubmed]
  4. Peptide YY inhibits intestinal Cl- secretion in experimental porcine cryptosporidiosis through a prostaglandin-activated neural pathway. Argenzio, R.A., Armstrong, M., Blikslager, A., Rhoads, J.M. J. Pharmacol. Exp. Ther. (1997) [Pubmed]
  5. Retrograde transport of intact poliovirus through the axon via the fast transport system. Ohka, S., Yang, W.X., Terada, E., Iwasaki, K., Nomoto, A. Virology (1998) [Pubmed]
  6. The circumventricular organs form a potential neural pathway for lactate sensitivity: implications for panic disorder. Shekhar, A., Keim, S.R. J. Neurosci. (1997) [Pubmed]
  7. A neurobiological basis of social attachment. Insel, T.R. The American journal of psychiatry. (1997) [Pubmed]
  8. Neurotrophic factors and Alzheimer's disease. Wainer, B.H. Neurobiol. Aging (1989) [Pubmed]
  9. Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system. Ortiz, J., Fitzgerald, L.W., Charlton, M., Lane, S., Trevisan, L., Guitart, X., Shoemaker, W., Duman, R.S., Nestler, E.J. Synapse (1995) [Pubmed]
  10. Ethanol affects hypothalamic neurons projecting to the hippocampus and inhibits dentate granule cell LTP. Wayner, M.J., Chitwood, R., Armstrong, D.L., Phelix, C. Alcohol (1997) [Pubmed]
  11. Inhibin beta in central neural pathways involved in the control of oxytocin secretion. Sawchenko, P.E., Plotsky, P.M., Pfeiffer, S.W., Cunningham, E.T., Vaughan, J., Rivier, J., Vale, W. Nature (1988) [Pubmed]
  12. Modulation of stress-induced ACTH release by corticotropin-releasing factor, catecholamines and vasopressin. Rivier, C., Vale, W. Nature (1983) [Pubmed]
  13. Autoradiographic distribution of substance P receptors in rat central nervous system. Quirion, R., Shults, C.W., Moody, T.W., Pert, C.B., Chase, T.N., O'Donohue, T.L. Nature (1983) [Pubmed]
  14. Spinothalamic lamina I neurons selectively sensitive to histamine: a central neural pathway for itch. Andrew, D., Craig, A.D. Nat. Neurosci. (2001) [Pubmed]
  15. Estrogen-induced remodeling of hypothalamic neural circuitry. Flanagan-Cato, L.M. Frontiers in neuroendocrinology. (2000) [Pubmed]
  16. Acute reserpine administration elicits long-term spontaneous oral dyskinesia. Sussman, A.N., Tran-Nguyen, L.T., Neisewander, J.L. Eur. J. Pharmacol. (1997) [Pubmed]
  17. Mapping of neural and signal transduction pathways for lordosis in the search for estrogen actions on the central nervous system. Kow, L.M., Pfaff, D.W. Behav. Brain Res. (1998) [Pubmed]
  18. Neuroblastoma: the result of multistep transformation? Tonini, G.P. Stem Cells (1993) [Pubmed]
  19. Effects of p-chlorophenylalanine on ventilatory control in goats. Mitchell, G.S., Smith, C.A., Vidruk, E.H., Jameson, L.C., Dempsey, J.A. Journal of applied physiology: respiratory, environmental and exercise physiology. (1983) [Pubmed]
  20. Corelease of galanin and NE from pancreatic sympathetic nerves during severe hypoglycemia in dogs. Havel, P.J., Mundinger, T.O., Veith, R.C., Dunning, B.E., Taborsky, G.J. Am. J. Physiol. (1992) [Pubmed]
  21. A genetic approach to visualization of multisynaptic neural pathways using plant lectin transgene. Yoshihara, Y., Mizuno, T., Nakahira, M., Kawasaki, M., Watanabe, Y., Kagamiyama, H., Jishage, K., Ueda, O., Suzuki, H., Tabuchi, K., Sawamoto, K., Okano, H., Noda, T., Mori, K. Neuron (1999) [Pubmed]
  22. Modulation of neural carbohydrate epitope expression in Drosophila melanogaster cells. Rendic, D., Linder, A., Paschinger, K., Borth, N., Wilson, I.B., Fabini, G. J. Biol. Chem. (2006) [Pubmed]
  23. Regional changes in rat brain angiotensinogen following bilateral nephrectomy. Gregory, T.J., Wallis, C.J., Printz, M.P. Hypertension (1982) [Pubmed]
  24. Are human milk long-chain polyunsaturated fatty acids related to visual and neural development in breast-fed term infants? Innis, S.M., Gilley, J., Werker, J. J. Pediatr. (2001) [Pubmed]
  25. The brain renin-angiotensin system: location and physiological roles. McKinley, M.J., Albiston, A.L., Allen, A.M., Mathai, M.L., May, C.N., McAllen, R.M., Oldfield, B.J., Mendelsohn, F.A., Chai, S.Y. Int. J. Biochem. Cell Biol. (2003) [Pubmed]
  26. Two specific markers for neural differentiation of embryonal carcinoma cells. Eddé, B., Jakob, H., Darmon, M. EMBO J. (1983) [Pubmed]
  27. Impaired hippocampal plasticity in mice lacking the Cbeta1 catalytic subunit of cAMP-dependent protein kinase. Qi, M., Zhuo, M., Skålhegg, B.S., Brandon, E.P., Kandel, E.R., McKnight, G.S., Idzerda, R.L. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  28. Effects of dietary monosaccharides on sympathetic nervous system activity in adipose tissues of male rats. Young, J.B., Weiss, J., Boufath, N. Diabetes (2004) [Pubmed]
  29. Effects of serotonin on the internal anal sphincter: in vivo manometric study in rats. Goldberg, M., Hanani, M., Nissan, S. Gut (1986) [Pubmed]
  30. Connecting the navigational clock to sun compass input in monarch butterfly brain. Sauman, I., Briscoe, A.D., Zhu, H., Shi, D., Froy, O., Stalleicken, J., Yuan, Q., Casselman, A., Reppert, S.M. Neuron (2005) [Pubmed]
  31. Serotonin released from intestinal enterochromaffin cells mediates luminal non-cholecystokinin-stimulated pancreatic secretion in rats. Li, Y., Hao, Y., Zhu, J., Owyang, C. Gastroenterology (2000) [Pubmed]
  32. Intragastric capsaicin stimulates colonic motility via a neural reflex in conscious dogs. Shibata, C., Sasaki, I., Naito, H., Tsuchiya, T., Takahashi, M., Ohtani, N., Matsuno, S. Gastroenterology (1995) [Pubmed]
  33. Cigarette smoke aggravates experimental colitis in rats. Galeazzi, F., Blennerhassett, P.A., Qiu, B., O'Byrne, P.M., Collins, S.M. Gastroenterology (1999) [Pubmed]
  34. Role of gastrin in bombesin-stimulated somatostatin release. Guo, Y.S., Thompson, J.C., Singh, P. Gastroenterology (1990) [Pubmed]
  35. PAR-2 agonists induce contraction of murine small intestine through neurokinin receptors. Zhao, A., Shea-Donohue, T. Am. J. Physiol. Gastrointest. Liver Physiol. (2003) [Pubmed]
  36. Interleukin-1beta activates specific populations of enteric neurons and enteric glia in the guinea pig ileum and colon. Tjwa, E.T., Bradley, J.M., Keenan, C.M., Kroese, A.B., Sharkey, K.A. Am. J. Physiol. Gastrointest. Liver Physiol. (2003) [Pubmed]
  37. Cyclic AMP phosphodiesterases are localized in regions of the mouse brain associated with reinforcement, movement, and affect. Cherry, J.A., Davis, R.L. J. Comp. Neurol. (1999) [Pubmed]
  38. Corticosterone release is heightened in food or water deprived oxytocin deficient male mice. Mantella, R.C., Vollmer, R.R., Amico, J.A. Brain Res. (2005) [Pubmed]
  39. The melanocortin agonist Melanotan-II reduces the orexigenic and adipogenic effects of neuropeptide Y (NPY) but does not affect the NPY-driven suppressive effects on the gonadotropic and somatotropic axes in the male rat. Raposinho, P.D., White, R.B., Aubert, M.L. J. Neuroendocrinol. (2003) [Pubmed]
  40. Relationship between regional brain angiotensinogen and local blood flow and volume in the adrenalectomized rat: application of approach to quantification of brain corticosterone receptors. Wallis, C.J., Gregory, T.J., Printz, M.P. J. Neurochem. (1982) [Pubmed]
  41. Receptors and pathways mediating the effects of prostaglandin E2 on airway tone. Tilley, S.L., Hartney, J.M., Erikson, C.J., Jania, C., Nguyen, M., Stock, J., McNeisch, J., Valancius, C., Panettieri, R.A., Penn, R.B., Koller, B.H. Am. J. Physiol. Lung Cell Mol. Physiol. (2003) [Pubmed]
  42. Morphine-like effects of clonidine on the EEG, slow wave sleep and behavior in the dog. Pickworth, W.B., Sharpe, L.G., Gupta, V.N. Eur. J. Pharmacol. (1982) [Pubmed]
  43. Methyl palmoxirate increases eating behavior and brain Fos-like immunoreactivity in rats. Horn, C.C., Friedman, M.I. Brain Res. (1998) [Pubmed]
  44. Effect of epidural bupivacaine on somatosensory evoked potentials after dermatomal stimulation. Lund, C., Selmar, P., Hansen, O.B., Hjortsø, N.C., Kehlet, H. Anesth. Analg. (1987) [Pubmed]
WikiGenes - Universities