Gene Review:
Mmp3 - matrix metallopeptidase 3
Rattus norvegicus
Synonyms:
MMP-3, Matrix metalloproteinase-3, PTR1 protein, SL-1, Stromelysin-1, ...
- Stromelysin-1 and gelatinase A are upregulated before TNF-alpha in LPS-stimulated neuroinflammation. Mun-Bryce, S., Lukes, A., Wallace, J., Lukes-Marx, M., Rosenberg, G.A. Brain Res. (2002)
- Purification and properties of extracellular matrix-degrading metallo-proteinase overproduced by Rous sarcoma virus-transformed rat liver cell line, and its identification as transin. Umenishi, F., Yasumitsu, H., Ashida, Y., Yamauti, J., Umeda, M., Miyazaki, K. J. Biochem. (1990)
- Spatial and temporal pattern of expression of interstitial collagenase, stromelysin/transin, gelatinase A, and TIMP-1 during experimental gastric ulcer healing. Calabrò, A., Grappone, C., Pellegrini, G., Evangelista, S., Tramontana, M., Schuppan, D., Herbst, H., Milani, S. Digestion (2004)
- Differential regulation of matrix metalloproteinase-3 gene expression in endometriotic lesions compared with endometrium. Cox, K.E., Piva, M., Sharpe-Timms, K.L. Biol. Reprod. (2001)
- NGF induction of the gene encoding the protease transin accompanies neuronal differentiation in PC12 cells. Machida, C.M., Rodland, K.D., Matrisian, L., Magun, B.E., Ciment, G. Neuron (1989)
- Rat hepatic lipocytes synthesize and secrete transin (stromelysin) in early primary culture. Vyas, S.K., Leyland, H., Gentry, J., Arthur, M.J. Gastroenterology (1995)
- The transcriptional corepressor NAB2 inhibits NGF-induced differentiation of PC12 cells. Qu, Z., Wolfraim, L.A., Svaren, J., Ehrengruber, M.U., Davidson, N., Milbrandt, J. J. Cell Biol. (1998)
- Expression of the transin, c-fos, and c-jun genes in rat transplantable osteosarcomas and malignant fibrous histiocytomas. Honoki, K., Tsutsumi, M., Tsujiuchi, T., Kondoh, S., Shiraiwa, K., Miyauchi, Y., Mii, Y., Tamai, S., Konishi, Y., Bowden, G.T. Mol. Carcinog. (1992)
- Transcription factor Ets-1 is essential for mesangial matrix remodeling. Mizui, M., Isaka, Y., Takabatake, Y., Sato, Y., Kawachi, H., Shimizu, F., Takahara, S., Ito, T., Imai, E. Kidney Int. (2006)
- Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts. Matrisian, L.M., Leroy, P., Ruhlmann, C., Gesnel, M.C., Breathnach, R. Mol. Cell. Biol. (1986)
- Peptide YY and neuropeptide Y induce villin expression, reduce adhesion, and enhance migration in small intestinal cells through the regulation of CD63, matrix metalloproteinase-3, and Cdc42 activity. Lee, M., Hadi, M., Halldén, G., Aponte, G.W. J. Biol. Chem. (2005)
- Proteolytic cleavage of extracellular secreted {alpha}-synuclein via matrix metalloproteinases. Sung, J.Y., Park, S.M., Lee, C.H., Um, J.W., Lee, H.J., Kim, J., Oh, Y.J., Lee, S.T., Paik, S.R., Chung, K.C. J. Biol. Chem. (2005)
- Elevation of hippocampal MMP-3 expression and activity during trauma-induced synaptogenesis. Kim, H.J., Fillmore, H.L., Reeves, T.M., Phillips, L.L. Exp. Neurol. (2005)
- Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures. Rosenberg, G.A., Cunningham, L.A., Wallace, J., Alexander, S., Estrada, E.Y., Grossetete, M., Razhagi, A., Miller, K., Gearing, A. Brain Res. (2001)
- Altered expression of matrix metalloproteinases within mineralizing bone cells in vitro in the presence of fluoride. Waddington, R.J., Langley, M.S. Connect. Tissue Res. (2003)
- NGF-induction of the metalloproteinase-transin/stromelysin in PC12 cells: involvement of multiple protein kinases. Machida, C.M., Scott, J.D., Ciment, G. J. Cell Biol. (1991)
- Mutational analysis of the transin (rat stromelysin) autoinhibitor region demonstrates a role for residues surrounding the "cysteine switch". Park, A.J., Matrisian, L.M., Kells, A.F., Pearson, R., Yuan, Z.Y., Navre, M. J. Biol. Chem. (1991)
- Cytokine interactions promote synergistic fibronectin accumulation by mesangial cells. Pawluczyk, I.Z., Harris, K.P. Kidney Int. (1998)
- Activation of matrix metalloproteinase-3 and agrin cleavage in cerebral ischemia/reperfusion. Solé, S., Petegnief, V., Gorina, R., Chamorro, A., Planas, A.M. J. Neuropathol. Exp. Neurol. (2004)
- Heparin selectively inhibits gene expression of matrix metalloproteinase transin in cultured mesangial cells. Kitamura, M., Maruyama, N., Mitarai, T., Nagasawa, R., Yokoo, T., Sakai, O. Biochem. Biophys. Res. Commun. (1994)
- Regulation of Peripheral Inflammation by Spinal p38 MAP Kinase in Rats. Boyle, D.L., Jones, T.L., Hammaker, D., Svensson, C.I., Rosengren, S., Albani, S., Sorkin, L., Firestein, G.S. PLoS Med. (2006)
- Dynamic changes in the expression of matrix metalloproteinases and their inhibitors, TIMPs, during hepatic fibrosis induced by alcohol in rats. Xu, G.F., Li, P.T., Wang, X.Y., Jia, X., Tian, D.L., Jiang, L.D., Yang, J.X. World J. Gastroenterol. (2004)
- Spatiotemporal expression patterns of metalloproteinases and their inhibitors in the postnatal developing rat cerebellum. Vaillant, C., Didier-Bazès, M., Hutter, A., Belin, M.F., Thomasset, N. J. Neurosci. (1999)
- The first stage of transforming growth factor beta1 activation is release of the large latent complex from the extracellular matrix of growth plate chondrocytes by matrix vesicle stromelysin-1 (MMP-3). Maeda, S., Dean, D.D., Gomez, R., Schwartz, Z., Boyan, B.D. Calcif. Tissue Int. (2002)
- Enhanced synthesis of gelatinase and stromelysin by myoepithelial cells during involution of the rat mammary gland. Dickson, S.R., Warburton, M.J. J. Histochem. Cytochem. (1992)
- Effect of unilateral nephrectomy on gene expression of metalloproteinases and their inhibitors. Koide, H., Nakamura, T., Ebihara, I., Tomino, Y. Nephron (1997)
- Differences in proliferation and invasion by normal, transformed and NF1 Schwann cell cultures are influenced by matrix metalloproteinase expression. Muir, D. Clin. Exp. Metastasis (1995)