Gene Review:
CAMK2G - calcium/calmodulin-dependent protein...
Homo sapiens
Synonyms:
CAMK, CAMK-II, CAMKG, CaM kinase II subunit gamma, CaMK-II subunit gamma, ...
- Human calcium/calmodulin-dependent protein kinase II gamma gene (CAMK2G): cloning, genomic structure and detection of variants in subjects with type II diabetes. Gloyn, A.L., Desai, M., Clark, A., Levy, J.C., Holman, R.R., Frayling, T.M., Hattersley, A.T., Ashcroft, S.J. Diabetologia (2002)
- Cloning and analysis of two new isoforms of multifunctional Ca2+/calmodulin-dependent protein kinase. Expression in multiple human tissues. Nghiem, P., Saati, S.M., Martens, C.L., Gardner, P., Schulman, H. J. Biol. Chem. (1993)
- CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy. Backs, J., Song, K., Bezprozvannaya, S., Chang, S., Olson, E.N. J. Clin. Invest. (2006)
- Ca2+/calmodulin-dependent protein kinase II: localization in the interphase nucleus and the mitotic apparatus of mammalian cells. Ohta, Y., Ohba, T., Miyamoto, E. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Global forebrain ischemia induces a posttranslational modification of multifunctional calcium- and calmodulin-dependent kinase II. Churn, S.B., Taft, W.C., Billingsley, M.S., Sankaran, B., DeLorenzo, R.J. J. Neurochem. (1992)
- Calcium/calmodulin-dependent protein kinase II immunostaining is preserved in Alzheimer's disease hippocampal neurons. Simonian, N.A., Elvhage, T., Czernik, A.J., Greengard, P., Hyman, B.T. Brain Res. (1994)
- Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy. Robitaille, J., MacDonald, M.L., Kaykas, A., Sheldahl, L.C., Zeisler, J., Dubé, M.P., Zhang, L.H., Singaraja, R.R., Guernsey, D.L., Zheng, B., Siebert, L.F., Hoskin-Mott, A., Trese, M.T., Pimstone, S.N., Shastry, B.S., Moon, R.T., Hayden, M.R., Goldberg, Y.P., Samuels, M.E. Nat. Genet. (2002)
- Mechanisms of organophosphorus ester-induced delayed neurotoxicity: type I and type II. Abou-Donia, M.B., Lapadula, D.M. Annu. Rev. Pharmacol. Toxicol. (1990)
- The CaM kinase II hypothesis for the storage of synaptic memory. Lisman, J. Trends Neurosci. (1994)
- Anti-immunoglobulin M activates nuclear calcium/calmodulin-dependent protein kinase II in human B lymphocytes. Valentine, M.A., Czernik, A.J., Rachie, N., Hidaka, H., Fisher, C.L., Cambier, J.C., Bomsztyk, K. J. Exp. Med. (1995)
- Activation of Ca2+/calmodulin-dependent protein kinase II by stimulation with bradykinin in neuroblastoma x glioma hybrid NG108-15 cells. Yamakawa, T., Fukunaga, K., Higashida, H., Miyamoto, E. Brain Res. (1992)
- Lithium-induced activation of Akt and CaM kinase II contributes to its neuroprotective action in a rat microsphere embolism model. Sasaki, T., Han, F., Shioda, N., Moriguchi, S., Kasahara, J., Ishiguro, K., Fukunaga, K. Brain Res. (2006)
- Role of calcium in inactivation of calcium/calmodulin dependent protein kinase II after cerebral ischemia. Hiestand, D.M., Haley, B.E., Kindy, M.S. J. Neurol. Sci. (1992)
- FK506 attenuates the post-ischemic perturbation of protein kinases and tyrosine phosphorylation in the gerbil hippocampal CA1 sectors. Katsura, K.I., Kurihara, J., Watanabe, M., Takahashi, K., Katayama, Y. Acta Neurochir. Suppl. (2003)
- Ca2+/calmodulin-dependent kinase II phosphorylates the epidermal growth factor receptor on multiple sites in the cytoplasmic tail and serine 744 within the kinase domain to regulate signal generation. Feinmesser, R.L., Wicks, S.J., Taverner, C.J., Chantry, A. J. Biol. Chem. (1999)
- Regulation of intrasteric inhibition of the multifunctional calcium/calmodulin-dependent protein kinase. Cruzalegui, F.H., Kapiloff, M.S., Morfin, J.P., Kemp, B.E., Rosenfeld, M.G., Means, A.R. Proc. Natl. Acad. Sci. U.S.A. (1992)
- Signal transduction molecules at the glutamatergic postsynaptic membrane. Kennedy, M.B. Brain Res. Brain Res. Rev. (1998)
- Calcium-dependent threonine phosphorylation of nonmuscle myosin in stimulated RBL-2H3 mast cells. Buxton, D.B., Adelstein, R.S. J. Biol. Chem. (2000)
- Human islets of Langerhans express multiple isoforms of calcium/calmodulin-dependent protein kinase II. Breen, M.A., Ashcroft, S.J. Biochem. Biophys. Res. Commun. (1997)
- A truncated isoform of Ca2+/calmodulin-dependent protein kinase II expressed in human islets of Langerhans may result from trans-splicing. Breen, M.A., Ashcroft, S.J. FEBS Lett. (1997)
- Expression of Ca2+/calmodulin-dependent protein kinase types II and IV, and reduced DNA synthesis due to the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenyl piperazine) in small cell lung carcinoma. Williams, C.L., Phelps, S.H., Porter, R.A. Biochem. Pharmacol. (1996)
- HER-2/c-erbB2 is phosphorylated by calmodulin-dependent protein kinase II on a single site in the cytoplasmic tail at threonine-1172. Feinmesser, R.L., Gray, K., Means, A.R., Chantry, A. Oncogene (1996)
- Inositol trisphosphate receptor: phosphorylation by protein kinase C and calcium calmodulin-dependent protein kinases in reconstituted lipid vesicles. Ferris, C.D., Huganir, R.L., Bredt, D.S., Cameron, A.M., Snyder, S.H. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Regulation by synapsin I and Ca(2+)-calmodulin-dependent protein kinase II of the transmitter release in squid giant synapse. Llinás, R., Gruner, J.A., Sugimori, M., McGuinness, T.L., Greengard, P. J. Physiol. (Lond.) (1991)
- Schwann cell lines derived from malignant peripheral nerve sheath tumors respond abnormally to platelet-derived growth factor-BB. Dang, I., DeVries, G.H. J. Neurosci. Res. (2005)
- Regulation of activating transcription factor-1 and the cAMP response element-binding protein by Ca2+/calmodulin-dependent protein kinases type I, II, and IV. Sun, P., Lou, L., Maurer, R.A. J. Biol. Chem. (1996)
- In vitro modulation of the interaction between HA95 and LAP2beta by cAMP signaling. Martins, S.B., Marstad, A., Collas, P. Biochemistry (2003)
- Membrane depolarization and calcium influx induce glucagon gene transcription in pancreatic islet cells through the cyclic AMP-responsive element. Schwaninger, M., Lux, G., Blume, R., Oetjen, E., Hidaka, H., Knepel, W. J. Biol. Chem. (1993)
- Activity and regulation by growth factors of calmodulin-dependent protein kinase III (elongation factor 2-kinase) in human breast cancer. Parmer, T.G., Ward, M.D., Yurkow, E.J., Vyas, V.H., Kearney, T.J., Hait, W.N. Br. J. Cancer (1999)
- Enhanced expression and activation of Ca(2+)/calmodulin-dependent protein kinase IV in hepatocellular carcinoma. Tamura, N., Tai, Y., Sugimoto, K., Kobayashi, R., Konishi, R., Nishioka, M., Masaki, T., Nagahata, S., Tokuda, M. Cancer (2000)
- Inactivation of smad-transforming growth factor beta signaling by Ca(2+)-calmodulin-dependent protein kinase II. Wicks, S.J., Lui, S., Abdel-Wahab, N., Mason, R.M., Chantry, A. Mol. Cell. Biol. (2000)
- Localization of the CAMKG gene encoding gamma isoforms of multifunctional calcium/calmodulin-dependent protein kinase (CaM kinase) to human chromosome 10 band q22 and mouse chromosome 14. Li, X., Nghiem, P., Schulman, H., Francke, U. Cytogenet. Cell Genet. (1994)
- Carbachol stimulates binding of a photoreactive calmodulin derivative to calmodulin-binding proteins in intact SK-N-SH human neuroblastoma cells. Mangels, L.A., Gnegy, M.E. J. Biol. Chem. (1992)
- Novel Ca2+/calmodulin-dependent protein kinase II gamma-subunit variants expressed in vascular smooth muscle, brain, and cardiomyocytes. Singer, H.A., Benscoter, H.A., Schworer, C.M. J. Biol. Chem. (1997)