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Chemical Compound Review

AC1MJ0TP     (2R,4S,5R,6R)-5-amino-2,4- dihydroxy-6-(1,2...

Synonyms: 114-04-5, Neuraminic acid
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Disease relevance of Neuraminic acid


High impact information on Neuraminic acid


Chemical compound and disease context of Neuraminic acid


Biological context of Neuraminic acid


Anatomical context of Neuraminic acid


Associations of Neuraminic acid with other chemical compounds


Gene context of Neuraminic acid


Analytical, diagnostic and therapeutic context of Neuraminic acid


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  2. A human monoclonal macroglobulin with specificity for alpha(2----8)-linked poly-N-acetyl neuraminic acid, the capsular polysaccharide of group B meningococci and Escherichia coli K1, which crossreacts with polynucleotides and with denatured DNA. Kabat, E.A., Nickerson, K.G., Liao, J., Grossbard, L., Osserman, E.F., Glickman, E., Chess, L., Robbins, J.B., Schneerson, R., Yang, Y.H. J. Exp. Med. (1986) [Pubmed]
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  10. The breast tumor-associated epitope defined by monoclonal antibody 3E1.2 is an O-linked mucin carbohydrate containing N-glycolylneuraminic acid. Devine, P.L., Clark, B.A., Birrell, G.W., Layton, G.T., Ward, B.G., Alewood, P.F., McKenzie, I.F. Cancer Res. (1991) [Pubmed]
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  13. Epithelial cell surface sites involved in the polyvalent adherence of Porphyromonas gingivalis: a convincing role for neuraminic acid and glucuronic acid. Agnani, G., Tricot-Doleux, S., Houalet, S., Bonnaure-Mallet, M. Infect. Immun. (2003) [Pubmed]
  14. Escherichia coli strains binding neuraminyl alpha 2-3 galactosides. Parkkinen, J., Finne, J., Achtman, M., Väisänen, V., Korhonen, T.K. Biochem. Biophys. Res. Commun. (1983) [Pubmed]
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  19. Inhibition of adhesion of S-fimbriated Escherichia coli to buccal epithelial cells by human milk fat globule membrane components: a novel aspect of the protective function of mucins in the nonimmunoglobulin fraction. Schroten, H., Hanisch, F.G., Plogmann, R., Hacker, J., Uhlenbruck, G., Nobis-Bosch, R., Wahn, V. Infect. Immun. (1992) [Pubmed]
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  22. Biochemical engineering of neural cell surfaces by the synthetic N-propanoyl-substituted neuraminic acid precursor. Schmidt, C., Stehling, P., Schnitzer, J., Reutter, W., Horstkorte, R. J. Biol. Chem. (1998) [Pubmed]
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  26. Characterization of a deaminated neuraminic acid-containing glycoprotein from the skin mucus of the loach, Misgurnus anguillicaudatus. Kimura, M., Hama, Y., Sumi, T., Asakawa, M., Rao, B.N., Horne, A.P., Li, S.C., Li, Y.T., Nakagawa, H. J. Biol. Chem. (1994) [Pubmed]
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  28. Wheat germ agglutinin and other selected lectins increase synthesis of decay-accelerating factor in human endothelial cells. Bryant, R.W., Granzow, C.A., Siegel, M.I., Egan, R.W., Billah, M.M. J. Immunol. (1991) [Pubmed]
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  30. Interaction of fibroblast growth factor-2 (FGF-2) with free gangliosides: biochemical characterization and biological consequences in endothelial cell cultures. Rusnati, M., Tanghetti, E., Urbinati, C., Tulipano, G., Marchesini, S., Ziche, M., Presta, M. Mol. Biol. Cell (1999) [Pubmed]
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  33. Multiple N-acetyl neuraminic acid synthetase (neuB) genes in Campylobacter jejuni: identification and characterization of the gene involved in sialylation of lipo-oligosaccharide. Linton, D., Karlyshev, A.V., Hitchen, P.G., Morris, H.R., Dell, A., Gregson, N.A., Wren, B.W. Mol. Microbiol. (2000) [Pubmed]
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  35. Beta-lactamase with high molecular weight: evidence for an interaction with neuraminic acid-containing structures. Jouvenot, M., Deschaseaux, M.L., Michel-Briand, Y., Adessi, G.L. J. Antimicrob. Chemother. (1984) [Pubmed]
  36. Biosynthesis of a nonphysiological sialic acid in different rat organs, using N-propanoyl-D-hexosamines as precursors. Kayser, H., Zeitler, R., Kannicht, C., Grunow, D., Nuck, R., Reutter, W. J. Biol. Chem. (1992) [Pubmed]
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