Gene Review:
Chrna7 - cholinergic receptor, nicotinic, alpha...
Mus musculus
Synonyms:
Acra7, Neuronal acetylcholine receptor subunit alpha-7, alpha7, alpha7 nicotinic receptor, alpha7-nAChR
Spencer,
Weil,
Hill,
Hussain,
Richardson,
Cusdin,
Chen,
Randall,
Bowers,
McClure-Begley,
Keller,
Paylor,
Collins,
Wehner,
Mousavi,
Nordberg,
Stefan,
Claiborn,
Stasiek,
Chai,
Ohta,
Longnecker,
Greally,
Nicholls,
Adams,
Yonchek,
Stitzel,
Bray,
Son,
Kumar,
Meizel,
van Westerloo,
Giebelen,
Florquin,
Bruno,
Larosa,
Ulloa,
Tracey,
van der Poll,
- The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice. van Westerloo, D.J., Giebelen, I.A., Florquin, S., Bruno, M.J., Larosa, G.J., Ulloa, L., Tracey, K.J., van der Poll, T. Gastroenterology (2006)
- Differential regulation of keratinocyte chemokinesis and chemotaxis through distinct nicotinic receptor subtypes. Chernyavsky, A.I., Arredondo, J., Marubio, L.M., Grando, S.A. J. Cell. Sci. (2004)
- Multiple calcium channels and kinases mediate alpha7 nicotinic receptor neuroprotection in PC12 cells. Ren, K., Puig, V., Papke, R.L., Itoh, Y., Hughes, J.A., Meyer, E.M. J. Neurochem. (2005)
- alpha7 Nicotinic acetylcholine receptor knockout selectively enhances ethanol-, but not beta-amyloid-induced neurotoxicity. de Fiebre, N.C., de Fiebre, C.M. Neurosci. Lett. (2005)
- Altered baroreflex responses in alpha7 deficient mice. Franceschini, D., Orr-Urtreger, A., Yu, W., Mackey, L.Y., Bond, R.A., Armstrong, D., Patrick, J.W., Beaudet, A.L., De Biasi, M. Behav. Brain Res. (2000)
- Targeted deletion of the kynurenine aminotransferase ii gene reveals a critical role of endogenous kynurenic acid in the regulation of synaptic transmission via alpha7 nicotinic receptors in the hippocampus. Alkondon, M., Pereira, E.F., Yu, P., Arruda, E.Z., Almeida, L.E., Guidetti, P., Fawcett, W.P., Sapko, M.T., Randall, W.R., Schwarcz, R., Tagle, D.A., Albuquerque, E.X. J. Neurosci. (2004)
- Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol. Bowers, B.J., McClure-Begley, T.D., Keller, J.J., Paylor, R., Collins, A.C., Wehner, J.M. Alcohol. Clin. Exp. Res. (2005)
- Impaired performance of alpha7 nicotinic receptor knockout mice in the five-choice serial reaction time task. Hoyle, E., Genn, R.F., Fernandes, C., Stolerman, I.P. Psychopharmacology (Berl.) (2006)
- Tolerance to nicotine in mice lacking alpha7 nicotinic receptors. Naylor, C., Quarta, D., Fernandes, C., Stolerman, I.P. Psychopharmacology (Berl.) (2005)
- Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. Wang, H., Liao, H., Ochani, M., Justiniani, M., Lin, X., Yang, L., Al-Abed, Y., Wang, H., Metz, C., Miller, E.J., Tracey, K.J., Ulloa, L. Nat. Med. (2004)
- Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Wang, H., Yu, M., Ochani, M., Amella, C.A., Tanovic, M., Susarla, S., Li, J.H., Wang, H., Yang, H., Ulloa, L., Al-Abed, Y., Czura, C.J., Tracey, K.J. Nature (2003)
- Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway. de Jonge, W.J., van der Zanden, E.P., The, F.O., Bijlsma, M.F., van Westerloo, D.J., Bennink, R.J., Berthoud, H.R., Uematsu, S., Akira, S., van den Wijngaard, R.M., Boeckxstaens, G.E. Nat. Immunol. (2005)
- Splenectomy inactivates the cholinergic antiinflammatory pathway during lethal endotoxemia and polymicrobial sepsis. Huston, J.M., Ochani, M., Rosas-Ballina, M., Liao, H., Ochani, K., Pavlov, V.A., Gallowitsch-Puerta, M., Ashok, M., Czura, C.J., Foxwell, B., Tracey, K.J., Ulloa, L. J. Exp. Med. (2006)
- Protection against MDMA-induced dopaminergic neurotoxicity in mice by methyllycaconitine: Involvement of nicotinic receptors. Chipana, C., Camarasa, J., Pubill, D., Escubedo, E. Neuropharmacology (2006)
- Mice deficient in CHRNA7, a subunit of the nicotinic acetylcholine receptor, produce sperm with impaired motility. Bray, C., Son, J.H., Kumar, P., Meizel, S. Biol. Reprod. (2005)
- Genetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes. Stefan, M., Claiborn, K.C., Stasiek, E., Chai, J.H., Ohta, T., Longnecker, R., Greally, J.M., Nicholls, R.D. BMC Genomics (2005)
- Cloning and mapping of the mouse alpha 7-neuronal nicotinic acetylcholine receptor. Orr-Urtreger, A., Seldin, M.F., Baldini, A., Beaudet, A.L. Genomics (1995)
- Development of hippocampal alpha7 nicotinic receptors in C3H and DBA/2 congenic mice. Adams, C.E., Yonchek, J.C., Stitzel, J.A. Brain Res. (2006)
- Expression of the alpha7, alpha4 and alpha3 nicotinic receptor subtype in the brain and adrenal medulla of transgenic mice carrying genes coding for human AChE and beta-amyloid. Mousavi, M., Nordberg, A. Int. J. Dev. Neurosci. (2006)
- Failure of nicotine-dependent enhancement of synaptic efficacy at Schaffer-collateral CA1 synapses of AD11 anti-nerve growth factor transgenic mice. Sola, E., Capsoni, S., Rosato-Siri, M., Cattaneo, A., Cherubini, E. Eur. J. Neurosci. (2006)
- Mouse muscle denervation increases expression of an alpha7 nicotinic receptor with unusual pharmacology. Tsuneki, H., Salas, R., Dani, J.A. J. Physiol. (Lond.) (2003)
- Mice homozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth. Orr-Urtreger, A., Broide, R.S., Kasten, M.R., Dang, H., Dani, J.A., Beaudet, A.L., Patrick, J.W. J. Neurochem. (2000)
- Transgenic mice over-expressing human beta-amyloid have functional nicotinic alpha 7 receptors. Spencer, J.P., Weil, A., Hill, K., Hussain, I., Richardson, J.C., Cusdin, F.S., Chen, Y.H., Randall, A.D. Neuroscience (2006)
- Cholinergic modulation of microglial activation by alpha 7 nicotinic receptors. Shytle, R.D., Mori, T., Townsend, K., Vendrame, M., Sun, N., Zeng, J., Ehrhart, J., Silver, A.A., Sanberg, P.R., Tan, J. J. Neurochem. (2004)
- A decrease of reelin expression as a putative vulnerability factor in schizophrenia. Impagnatiello, F., Guidotti, A.R., Pesold, C., Dwivedi, Y., Caruncho, H., Pisu, M.G., Uzunov, D.P., Smalheiser, N.R., Davis, J.M., Pandey, G.N., Pappas, G.D., Tueting, P., Sharma, R.P., Costa, E. Proc. Natl. Acad. Sci. U.S.A. (1998)
- Differential expression of alpha-bungarotoxin-sensitive neuronal nicotinic receptors in adrenergic chromaffin cells: a role for transcription factor Egr-1. Criado, M., Domínguez del Toro, E., Carrasco-Serrano, C., Smillie, F.I., Juíz, J.M., Viniegra, S., Ballesta, J.J. J. Neurosci. (1997)
- Involvement of nicotinic acetylcholine receptors in suppression of antimicrobial activity and cytokine responses of alveolar macrophages to Legionella pneumophila infection by nicotine. Matsunaga, K., Klein, T.W., Friedman, H., Yamamoto, Y. J. Immunol. (2001)
- Characterization of nicotinic acetylcholine receptors expressed in primary cultures of cerebellar granule cells. Didier, M., Berman, S.A., Lindstrom, J., Bursztajn, S. Brain Res. Mol. Brain Res. (1995)