Gene Review:
Pdgfa - platelet-derived growth factor alpha...
Rattus norvegicus
Synonyms:
PDGF subunit A, PDGF-1, Platelet-derived growth factor A chain, Platelet-derived growth factor alpha polypeptide, Platelet-derived growth factor subunit A, ...
- Insulin but not PDGF relies on actin remodeling and on VAMP2 for GLUT4 translocation in myoblasts. Török, D., Patel, N., Jebailey, L., Thong, F.S., Randhawa, V.K., Klip, A., Rudich, A. J. Cell. Sci. (2004)
- Suppression of early growth response factor-1 with egr-1 antisense oligodeoxynucleotide aggravates experimental duodenal ulcers. Khomenko, T., Szabo, S., Deng, X., Jadus, M.R., Ishikawa, H., Osapay, K., Sandor, Z., Chen, L. Am. J. Physiol. Gastrointest. Liver Physiol. (2006)
- Increased expression of PDGF A- and B-chain genes in rat lungs with hypoxic pulmonary hypertension. Katayose, D., Ohe, M., Yamauchi, K., Ogata, M., Shirato, K., Fujita, H., Shibahara, S., Takishima, T. Am. J. Physiol. (1993)
- Ca2+ channel activation by platelet-derived growth factor-induced tyrosine phosphorylation and Ras guanine triphosphate-binding proteins in rat glomerular mesangial cells. Ma, H., Matsunaga, H., Li, B., Schieffer, B., Marrero, M.B., Ling, B.N. J. Clin. Invest. (1996)
- Expression of platelet-derived growth factor after intrastriatal ibotenic acid injury. Sjöborg, M., Pietz, K., Ahgren, A., Yamada, N., Lindvall, O., Funa, K., Odin, P. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (1998)
- PAF and PDGF increase cytosolic [Ca2+] and phospholipase activity in mesangial cells. Bonventre, J.V., Weber, P.C., Gronich, J.H. Am. J. Physiol. (1988)
- A role for platelet-derived growth factor in normal gliogenesis in the central nervous system. Richardson, W.D., Pringle, N., Mosley, M.J., Westermark, B., Dubois-Dalcq, M. Cell (1988)
- Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors. Huang, J.S., Huang, S.S., Deuel, T.F. Cell (1984)
- Immunohistochemical characterization of glomerular PDGF B-chain and PDGF beta-receptor expression in diabetic rats. Nakagawa, H., Sasahara, M., Haneda, M., Koya, D., Hazama, F., Kikkawa, R. Diabetes Res. Clin. Pract. (2000)
- Platelet-derived growth factor and growth-related genes in rat lung. II. Effect of exposure to 85% O2. Han, R.N., Buch, S., Freeman, B.A., Post, M., Tanswell, A.K. Am. J. Physiol. (1992)
- Angiotensin II stimulates MAP kinase kinase kinase activity in vascular smooth muscle cells, Role of Raf. Liao, D.F., Duff, J.L., Daum, G., Pelech, S.L., Berk, B.C. Circ. Res. (1996)
- Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors. Pietras, K., Ostman, A., Sjöquist, M., Buchdunger, E., Reed, R.K., Heldin, C.H., Rubin, K. Cancer Res. (2001)
- Effects of hypertension and aging on platelet-derived growth factor and platelet-derived growth factor receptor expression in rat aorta and heart. Sarzani, R., Arnaldi, G., Takasaki, I., Brecher, P., Chobanian, A.V. Hypertension (1991)
- NHERF2 increases platelet-derived growth factor-induced proliferation through PI-3-kinase/Akt-, ERK-, and Src family kinase-dependent pathway. Jung Kang, Y., Su Jeon, E., Jin Lee, H., Oh, Y.S., Suh, P.G., Sup Jung, J., Donowitz, M., Ho Kim, J. Cell. Signal. (2004)
- The phyto-chemical (-)-epigallocatechin gallate suppresses gene expression of epidermal growth factor receptor in rat hepatic stellate cells in vitro by reducing the activity of Egr-1. Fu, Y., Chen, A. Biochem. Pharmacol. (2006)
- Expression patterns of PDGF-A, -B, -C and -D and the PDGF-receptors alpha and beta in activated rat hepatic stellate cells (HSC). Breitkopf, K., Roeyen, C., Sawitza, I., Wickert, L., Floege, J., Gressner, A.M. Cytokine (2005)
- Blood lipid mediator sphingosine 1-phosphate potently stimulates platelet-derived growth factor-A and -B chain expression through S1P1-Gi-Ras-MAPK-dependent induction of Kruppel-like factor 5. Usui, S., Sugimoto, N., Takuwa, N., Sakagami, S., Takata, S., Kaneko, S., Takuwa, Y. J. Biol. Chem. (2004)
- The Effect of FK778 on Acute Rat Renal Allograft Rejection and Expression of Platelet-Derived Growth Factor and Transforming Growth Factor-Beta. Rintala, J.M., Savikko, J., Rintala, S.E., von Willebrand, E. Transplant. Proc. (2006)
- Chrysotile asbestos upregulates gene expression and production of alpha-receptors for platelet-derived growth factor (PDGF-AA) on rat lung fibroblasts. Bonner, J.C., Goodell, A.L., Coin, P.G., Brody, A.R. J. Clin. Invest. (1993)
- Angiotensin II induces transactivation of two different populations of the platelet-derived growth factor beta receptor. Key role for the p66 adaptor protein Shc. Heeneman, S., Haendeler, J., Saito, Y., Ishida, M., Berk, B.C. J. Biol. Chem. (2000)
- NF1/X represses PDGF A-chain transcription by interacting with Sp1 and antagonizing Sp1 occupancy of the promoter. Rafty, L.A., Santiago, F.S., Khachigian, L.M. EMBO J. (2002)
- Carvedilol inhibits platelet-derived growth factor-induced extracellular matrix synthesis by inhibiting cellular reactive oxygen species and mitogen-activated protein kinase activation. Park, J., Ha, H., Kim, M.S., Ahn, H.J., Huh, K.H., Kim, Y.S. J. Heart Lung Transplant. (2006)
- Expression and developmental control of platelet-derived growth factor A-chain and B-chain/Sis genes in rat aortic smooth muscle cells. Majesky, M.W., Benditt, E.P., Schwartz, S.M. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Induction of PDGF receptor-alpha in rat myofibroblasts during pulmonary fibrogenesis in vivo. Bonner, J.C., Lindroos, P.M., Rice, A.B., Moomaw, C.R., Morgan, D.L. Am. J. Physiol. (1998)
- Effects of PDGF A-chain antisense oligodeoxynucleotides on growth of cardiovascular organs in stroke-prone spontaneously hypertensive rats. Kishioka, H., Fukuda, N., Wen-Yang, H., Nakayama, M., Watanabe, Y., Kanmatsuse, K. Am. J. Hypertens. (2001)
- Crosstalk between PDGF and IGF-I receptors in rat liver myofibroblasts: implication for liver fibrogenesis. Novosyadlyy, R., Dudas, J., Pannem, R., Ramadori, G., Scharf, J.G. Lab. Invest. (2006)
- Expression and localization of platelet-derived growth factor ligand and receptor protein during acute and chronic rejection of rat cardiac allografts. Lemström, K.B., Koskinen, P.K. Circulation (1997)
- Neuroblastoma cells express c-sis and produce a transforming growth factor antigenically related to the platelet-derived growth factor. van Zoelen, E.J., van de Ven, W.J., Franssen, H.J., van Oostwaard, T.M., van der Saag, P.T., Heldin, C.H., de Laat, S.W. Mol. Cell. Biol. (1985)