Gene Review:
Il1r1 - interleukin 1 receptor, type I
Rattus norvegicus
Synonyms:
CD121 antigen-like family member A, IL-1R-1, IL-1R-alpha, IL-1RT-1, IL-1RT1, ...
- Chronic hypoxia modulates the interleukin-1beta-stimulated inducible nitric oxide synthase pathway in cardiac myocytes. Kacimi, R., Long, C.S., Karliner, J.S. Circulation (1997)
- Brain tumor development in rats is associated with changes in central nervous system cytokine and neuropeptide systems. Ilyin, S.E., Gayle, D., González-Gómez, I., Miele, M.E., Plata-Salamán, C.R. Brain Res. Bull. (1999)
- IL-1 up-regulates osteopontin expression in experimental crescentic glomerulonephritis in the rat. Yu, X.Q., Fan, J.M., Nikolic-Paterson, D.J., Yang, N., Mu, W., Pichler, R., Johnson, R.J., Atkins, R.C., Lan, H.Y. Am. J. Pathol. (1999)
- Central cyclooxygenase inhibitors reduced IL-1beta-induced hyperalgesia in temporomandibular joint of freely moving rats. Ahn, D.K., Chae, J.M., Choi, H.S., Kyung, H.M., Kwon, O.W., Park, H.S., Youn, D.H., Bae, Y.C. Pain (2005)
- 3,4-Methylenedioxymethamphetamine increases interleukin-1beta levels and activates microglia in rat brain: studies on the relationship with acute hyperthermia and 5-HT depletion. Orio, L., O'Shea, E., Sanchez, V., Pradillo, J.M., Escobedo, I., Camarero, J., Moro, M.A., Green, A.R., Colado, M.I. J. Neurochem. (2004)
- Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase. Corbett, J.A., McDaniel, M.L. J. Exp. Med. (1995)
- The morphogenic/cytotoxic and prostaglandin-stimulating activities of interleukin-1 beta in the rat ovary are nitric oxide independent. Ben-Shlomo, I., Adashi, E.Y., Payne, D.W. J. Clin. Invest. (1994)
- Induction of plasminogen activator inhibitor type 1 and type 1 collagen expression in rat cardiac microvascular endothelial cells by interleukin-1 and its dependence on oxygen-centered free radicals. Okada, H., Woodcock-Mitchell, J., Mitchell, J., Sakamoto, T., Marutsuka, K., Sobel, B.E., Fujii, S. Circulation (1998)
- Interleukin-1 mediates a rapid inflammatory response after injection of adenoviral vectors into the brain. Cartmell, T., Southgate, T., Rees, G.S., Castro, M.G., Lowenstein, P.R., Luheshi, G.N. J. Neurosci. (1999)
- Activation of vagal afferents after intravenous injection of interleukin-1beta: role of endogenous prostaglandins. Ek, M., Kurosawa, M., Lundeberg, T., Ericsson, A. J. Neurosci. (1998)
- Evaluation of an interleukin-1 receptor antagonist in the rat acetic acid-induced colitis model. Thomas, T.K., Will, P.C., Srivastava, A., Wilson, C.L., Harbison, M., Little, J., Chesonis, R.S., Pignatello, M., Schmolze, D., Symington, J. Agents Actions (1991)
- Granulocyte infiltration in experimental colitis in the rat is interleukin-1 dependent and leukotriene independent. McCafferty, D.M., Rioux, K.J., Wallace, J.L. Eicosanoids (1992)
- Up-regulation of IL-1 receptor through PI3K/Akt is essential for the induction of iNOS gene expression in hepatocytes. Teshima, S., Nakanishi, H., Nishizawa, M., Kitagawa, K., Kaibori, M., Yamada, M., Habara, K., Kwon, A.H., Kamiyama, Y., Ito, S., Okumura, T. J. Hepatol. (2004)
- Interleukin-1-induced neurotoxicity is mediated by glia and requires caspase activation and free radical release. Thornton, P., Pinteaux, E., Gibson, R.M., Allan, S.M., Rothwell, N.J. J. Neurochem. (2006)
- Strain-dependent difference in inducible nitric oxide synthesis (iNOS) expression in rat pancreatic islets correlates with interferon regulating factor 1 (IRF-1) and heat shock protein 70 (HSP70) expression. Johannesen, J., Pociot, F., Karlsen, A.E., Mandrup-Poulsen, T., Nerup, J. Eur. Cytokine Netw. (2001)
- Adenoviral overexpression of interleukin-1 receptor antagonist protein increases beta-cell replication in rat pancreatic islets. Téllez, N., Montolio, M., Biarnés, M., Castaño, E., Soler, J., Montanya, E. Gene Ther. (2005)
- Induction of nitric oxide synthase activity by cytokines in ventricular myocytes is necessary but not sufficient to decrease contractile responsiveness to beta-adrenergic agonists. Ungureanu-Longrois, D., Balligand, J.L., Simmons, W.W., Okada, I., Kobzik, L., Lowenstein, C.J., Kunkel, S.L., Michel, T., Kelly, R.A., Smith, T.W. Circ. Res. (1995)
- Interleukin-1beta enhances GABAA receptor cell-surface expression by a phosphatidylinositol 3-kinase/Akt pathway: relevance to sepsis-associated encephalopathy. Serantes, R., Arnalich, F., Figueroa, M., Salinas, M., Andrés-Mateos, E., Codoceo, R., Renart, J., Matute, C., Cavada, C., Cuadrado, A., Montiel, C. J. Biol. Chem. (2006)
- Amphotericin B potentiates the activation of inducible nitric oxide synthase and causes nitric oxide-dependent mitochondrial dysfunction in cytokine-treated rodent astrocytes. Trajkovic, V., Markovic, M., Samardzic, T., Miljkovic, D.J., Popadic, D., Mostarica Stojkovic, M. Glia (2001)
- Visualization and characterization of interleukin 1 receptors in brain. Farrar, W.L., Kilian, P.L., Ruff, M.R., Hill, J.M., Pert, C.B. J. Immunol. (1987)
- In vivo transfer of engineered macrophages into the glomerulus: endogenous TGF-beta-mediated defense against macrophage-induced glomerular cell activation. Sütö, T.S., Fine, L.G., Shimizu, F., Kitamura, M. J. Immunol. (1997)
- Pirfenidone inhibits the induction of iNOS stimulated by interleukin-1beta at a step of NF-kappaB DNA binding in hepatocytes. Nakanishi, H., Kaibori, M., Teshima, S., Yoshida, H., Kwon, A.H., Kamiyama, Y., Nishizawa, M., Ito, S., Okumura, T. J. Hepatol. (2004)
- Induction of guanosine triphosphate-cyclohydrolase by follicle-stimulating hormone enhances interleukin-1 beta-stimulated nitric oxide synthase activity in granulosa cells. Tabraue, C., Diaz Peñate, R., Gallardo, G., Hernandez, I., Quintana, J., Lopez Blanco, F., Gonzalez Reyes, J., Fanjul, L.F., Ruiz de Galarreta, C.M. Endocrinology (1997)
- Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes. Blanco, A.M., Vallés, S.L., Pascual, M., Guerri, C. J. Immunol. (2005)
- Modulation of rat mast cell reactivity by IL-1 beta. Divergent effects on nitric oxide and platelet-activating factor release. Hogaboam, C.M., Befus, A.D., Wallace, J.L. J. Immunol. (1993)
- Interleukin-1 beta stimulates ovarian phosphoipase A2 (PLA2) expression and activity: up-regulation of both secretory and cytosolic PLA2. Kol, S., Ben-Shlomo, I., Ando, M., Payne, D.W., Adashi, E.Y. Endocrinology (1997)
- IL-1 beta, IL-1 receptor type I and iNOS gene expression in rat brain vasculature and perivascular areas. Wong, M.L., Bongiorno, P.B., al-Shekhlee, A., Esposito, A., Khatri, P., Licinio, J. Neuroreport (1996)
- Dibutyryl cyclic AMP and inflammatory cytokines mediate C3 expression in Schwann cells. Dashiell, S.M., Vanguri, P., Koski, C.L. Glia (1997)
- The inhibitor cytokine interleukin-1 receptor antagonist synergistically augments cyclosporine immunosuppression in a rat cardiac allograft model. Shiraishi, M., Csete, M., Yasunaga, C., McDiarmid, S.V., Vannice, J.L., Busuttil, R.W., Shaked, A. J. Surg. Res. (1995)
- Rat homolog of mouse interleukin-1 receptor accessory protein: cloning, localization and modulation studies. Liu, C., Chalmers, D., Maki, R., De Souza, E.B. J. Neuroimmunol. (1996)
- Insulin-like growth factor I affects the intraovarian interleukin-1 system: evidence for suppression of type I interleukin-1 receptor expression and enhancement of secretory phospholipase A2 expression and activity. Kol, S., Ben-Shlomo, I., Ando, M., Adashi, E.Y. Mol. Hum. Reprod. (1997)
- A novel nonhepatic hydroxycholesterol 7 alpha-hydroxylase that is markedly stimulated by interleukin-1 beta. Characterization in the immature rat ovary. Payne, D.W., Shackleton, C., Toms, H., Ben-Shlomo, I., Kol, S., deMoura, M., Strauss, J.F., Adashi, E.Y. J. Biol. Chem. (1995)
- Learning modulation by endogenous hippocampal IL-1: blockade of endogenous IL-1 facilitates memory formation. Depino, A.M., Alonso, M., Ferrari, C., del Rey, A., Anthony, D., Besedovsky, H., Medina, J.H., Pitossi, F. Hippocampus. (2004)
- Intracerebroventricular interleukin-1 alpha increases immunocyte beta-endorphin concentrations in the rat: involvement of corticotropin-releasing hormone, catecholamines, and serotonin. Sacerdote, P., Bianchi, M., Manfredi, B., Panerai, A.E. Endocrinology (1994)
- Signaling pathways of interleukin-1 actions in the brain: anatomical distribution of phospho-ERK1/2 in the brain of rat treated systemically with interleukin-1beta. Nadjar, A., Combe, C., Busquet, P., Dantzer, R., Parnet, P. Neuroscience (2005)
- The involvement of bradykinin B1 and B2 receptor mechanisms in cytokine-induced mechanical hyperalgesia in the rat. Davis, A.J., Perkins, M.N. Br. J. Pharmacol. (1994)
- Concordant and discordant interleukin-1-mediated signaling in lung fibroblast thy-1 subpopulations. Hagood, J.S., Mangalwadi, A., Guo, B., MacEwen, M.W., Salazar, L., Fuller, G.M. Am. J. Respir. Cell Mol. Biol. (2002)
- Interleukin-4 ameliorates experimental glomerulonephritis and up-regulates glomerular gene expression of IL-1 decoy receptor. Tam, F.W., Smith, J., Karkar, A.M., Pusey, C.D., Rees, A.J. Kidney Int. (1997)
- Interleukin-1 beta (IL-1 beta) modulates prostaglandin production and the natural IL-1 receptor antagonist inhibits ovulation in the optimally stimulated rat ovarian perfusion model. Peterson, C.M., Hales, H.A., Hatasaka, H.H., Mitchell, M.D., Rittenhouse, L., Jones, K.P. Endocrinology (1993)
- Expression of interleukin-1 beta in rat dorsal root ganglia. Copray, J.C., Mantingh, I., Brouwer, N., Biber, K., Küst, B.M., Liem, R.S., Huitinga, I., Tilders, F.J., Van Dam, A.M., Boddeke, H.W. J. Neuroimmunol. (2001)
- The MAP kinase cascades are activated during post-ischemic liver reperfusion. Bendinelli, P., Piccoletti, R., Maroni, P., Bernelli-Zazzera, A. FEBS Lett. (1996)