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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Rats, Nude

 
 
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Disease relevance of Rats, Nude

 

Psychiatry related information on Rats, Nude

  • Furthermore, nude rats bearing LC-6-JCK showed reduced locomotor activity, less eating and drinking and low blood phosphorus; and anti-PTHrP antibody restored them [6].
 

High impact information on Rats, Nude

 

Chemical compound and disease context of Rats, Nude

 

Biological context of Rats, Nude

 

Anatomical context of Rats, Nude

 

Associations of Rats, Nude with chemical compounds

  • Furthermore, no significant increase in substance P concentration was seen in congenitally athymic rats infected with T. spiralis [25].
  • However, when athymic rats were reconstituted with splenic mononuclear cells, increased tension to carbachol or 5-hydroxytryptamine was observed after infection [26].
  • Blood histamine concentration increased significantly in Ws/Ws and +/+ rats but did not increase in nude rats [27].
  • In nude rats carrying both a C6 and a C6tk tumor, the average ratio of tracer accumulation between the tumors was 15 +/- 5 at 2 h postinjection [28].
  • Likewise, the antitumor effects of linomide are also produced in prostatic cancer-bearing athymic nude rats [29].
 

Gene context of Rats, Nude

  • We found previously that expression of rat Crry on a human tumor cell line enhances tumorigenicity in nude rats [30].
  • Variant forms of rat epidermal growth factor present in the urine of nude rats bearing human tumors [31].
  • The average volume of new bone induced by 10(7) PFU of BMP vector in athymic nude rats was 0.37+/-0.03 cm(3) for ADCMVBMP-2, 0.89+/-0.07 cm(3) for ADCMVBMP-4, 1.02+/-0.07 cm(3) for ADCMVBMP-6, 0.24+/-0.05 cm(3) for ADCMVBMP-7, and 0.63+/-0.07 cm(3) for ADCMVBMP-9 [32].
  • Athymic rats given Ad-IL-1ra (n = 6) had serum levels of 493 +/- 62 pg/ml IL-1ra 14 days after transduction, and IL-1ra was detected for up to 98 days [33].
  • Moreover, immunohistological analysis of ischemic limbs from nude rats revealed that VEGF is also released from recruited human EPC in vivo [34].
 

Analytical, diagnostic and therapeutic context of Rats, Nude

References

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  18. In vivo endochondral bone formation using a bone morphogenetic protein 2 adenoviral vector. Alden, T.D., Pittman, D.D., Hankins, G.R., Beres, E.J., Engh, J.A., Das, S., Hudson, S.B., Kerns, K.M., Kallmes, D.F., Helm, G.A. Hum. Gene Ther. (1999) [Pubmed]
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  21. Molecular biologic characteristics of seven new cell lines of squamous cell carcinomas of the head and neck and comparison to fresh tumor tissue. Welkoborsky, H.J., Jacob, R., Riazimand, S.H., Bernauer, H.S., Mann, W.J. Oncology (2003) [Pubmed]
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  23. Natural killer cell- and macrophage-mediated rejection of concordant xenografts in the absence of T and B cell responses. Lin, Y., Vandeputte, M., Waer, M. J. Immunol. (1997) [Pubmed]
  24. In vivo assessment of isolated pancreatic islet viability using the streptozotocin-induced diabetic nude rat. Lake, S.P., Chamberlain, J., Husken, P., Bell, P.R., James, R.F. Diabetologia (1988) [Pubmed]
  25. Increased levels of substance P in the myenteric plexus of Trichinella-infected rats. Swain, M.G., Agro, A., Blennerhassett, P., Stanisz, A., Collins, S.M. Gastroenterology (1992) [Pubmed]
  26. T-lymphocyte modulation of intestinal muscle function in the Trichinella-infected rat. Vermillion, D.L., Ernst, P.B., Collins, S.M. Gastroenterology (1991) [Pubmed]
  27. Infection of Nippostrongylus brasiliensis induces normal increase of basophils in mast cell-deficient Ws/Ws rats with a small deletion at the kinase domain of c-kit. Kasugai, T., Okada, M., Morimoto, M., Arizono, N., Maeyama, K., Yamada, M., Tei, H., Dohmae, K., Onoue, H., Newlands, G.F. Blood (1993) [Pubmed]
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  30. Expression of rat complement control protein Crry on tumor cells inhibits rat natural killer cell-mediated cytotoxicity. Caragine, T.A., Imai, M., Frey, A.B., Tomlinson, S. Blood (2002) [Pubmed]
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  32. Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat. Li, J.Z., Li, H., Sasaki, T., Holman, D., Beres, B., Dumont, R.J., Pittman, D.D., Hankins, G.R., Helm, G.A. Gene Ther. (2003) [Pubmed]
  33. Systemic delivery of the interleukin-1 receptor antagonist protein using a new strategy of direct adenoviral-mediated gene transfer to skeletal muscle capillary endothelium in the isolated rat hindlimb. Welling, T.H., Davidson, B.L., Zelenock, J.A., Stanley, J.C., Gordon, D., Roessler, B.J., Messina, L.M. Hum. Gene Ther. (1996) [Pubmed]
  34. Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells. Urbich, C., Aicher, A., Heeschen, C., Dernbach, E., Hofmann, W.K., Zeiher, A.M., Dimmeler, S. J. Mol. Cell. Cardiol. (2005) [Pubmed]
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