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MeSH Review

Chemistry, Clinical

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Disease relevance of Chemistry, Clinical


High impact information on Chemistry, Clinical


Chemical compound and disease context of Chemistry, Clinical


Biological context of Chemistry, Clinical


Anatomical context of Chemistry, Clinical

  • Red blood cell (RBC) electrolyte concentrations were determined, with a method that can be applied easily in any clinical chemistry laboratory, in 18 patients not on digoxin therapy and 37 patients on maintenance digoxin therapy for various diagnoses [20].
  • International Federation of Clinical Chemistry. Committee on Standards. Expert Panel on Enzymes. Approved recommendation (1978) on IFCC methods for the measurement of catalytic concentration of enzymes. Part 1. General considerations concerning the determination of the catalytic concentration of an enzyme in the blood serum or plasma of man [21].
  • Blood samples for clinical chemistry and haematology were obtained and lungs, heart, adrenals, kidneys, liver, spleen, stomach, intestine, testes (males), uterus and ovaries (females) were weighed and prepared for histopathological examination [22].

Associations of Chemistry, Clinical with chemical compounds

  • For these reasons, the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) agreed to establish a Committee on 'Standardization of Markers of Cardiac Damage' (C-SMCD) [23].
  • References and texts in the fields of diabetes and clinical chemistry commonly report that ascorbic acid when given orally or parenterally gives a false-positive reaction to the copper reduction glucose test (Clinitest) [24].
  • Physiological and clinical chemistry of biopterin [25].
  • We compared two officially recommended methods for determination of aspartate aminotransferase (EC that of the International Federation of Clinical Chemistry (IFCC) and that of the Deutsche Gesellschaft für Klinische Chemie (DGKC) [26].
  • TIBC values were determined for 49 healthy individuals and 148 patients with this modified TIBC assay and with a commercial, fully automated TIBC method (Dimension clinical chemistry system), and calculation of TIBC based on the sum of the serum iron and unsaturated iron-binding capacity was performed for 97 patients [27].

Gene context of Chemistry, Clinical


Analytical, diagnostic and therapeutic context of Chemistry, Clinical


  1. Tolerability profile of zolmitriptan (Zomig; 311C90), a novel dual central and peripherally acting 5HT1B/1D agonist. International clinical experience based on > 3000 subjects treated with zolmitriptan. Edmeads, J.G., Millson, D.S. Cephalalgia : an international journal of headache. (1997) [Pubmed]
  2. Surgically induced uremia in rats. II: Osseous PTH-susceptible signaling systems as predictors of bone resorption. Jablonski, G., Danielsen, C.C., Mosekilde, L., Gordeladze, J.O. Calcif. Tissue Int. (1994) [Pubmed]
  3. Study of haptoglobin-hemoglobin complexes by titration curves, capillary electrophoresis and capillary isoelectric focusing. Righetti, P.G., Conti, M., Gelfi, C. Journal of chromatography. A. (1997) [Pubmed]
  4. 14-Week toxicity and cell proliferation of methyleugenol administered by gavage to F344 rats and B6C3F1 mice. Abdo, K.M., Cunningham, M.L., Snell, M.L., Herbert, R.A., Travlos, G.S., Eldridge, S.R., Bucher, J.R. Food Chem. Toxicol. (2001) [Pubmed]
  5. Monitoring acrylic fiber workers for liver toxicity and exposure to dimethylacetamide. 2. Serum clinical chemistry results of dimethylacetamide-exposed workers. Spies, G.J., Rhyne, R.H., Evans, R.A., Wetzel, K.E., Ragland, D.T., Turney, H.G., Leet, T.L., Oglesby, J.L. J. Occup. Environ. Med. (1995) [Pubmed]
  6. Associations of plasma high-density lipoprotein cholesterol with clinical chemistry data. Patten, R.L., Hewitt, D., Waldman, G.T., Jones, G., Little, J.A. Circulation (1980) [Pubmed]
  7. Interleukin-1 receptor type I gene-deficient bile duct-ligated mice are partially protected against endotoxin. Sewnath, M.E., Van Der Poll, T., Ten Kate, F.J., Van Noorden, C.J., Gouma, D.J. Hepatology (2002) [Pubmed]
  8. Absence of thrombin-activatable fibrinolysis inhibitor protects against sepsis-induced liver injury in mice. Renckens, R., Roelofs, J.J., ter Horst, S.A., van 't Veer, C., Havik, S.R., Florquin, S., Wagenaar, G.T., Meijers, J.C., van der Poll, T. J. Immunol. (2005) [Pubmed]
  9. IL-10-deficient mice demonstrate multiple organ failure and increased mortality during Escherichia coli peritonitis despite an accelerated bacterial clearance. Sewnath, M.E., Olszyna, D.P., Birjmohun, R., ten Kate, F.J., Gouma, D.J., van Der Poll, T. J. Immunol. (2001) [Pubmed]
  10. Age-related differences in the toxicity of ochratoxin A in female rats. Dortant, P.M., Peters-Volleberg, G.W., Van Loveren, H., Marquardt, R.R., Speijers, G.J. Food Chem. Toxicol. (2001) [Pubmed]
  11. Optimization and evaluation of cardiac enzymes and isoenzymes measured on a random access analyzer. Savory, J., Stallings, R.G., Bruns, D.E., Savory, M.G., Margrey, M., Boyd, J.C. Ann. Clin. Lab. Sci. (1985) [Pubmed]
  12. One-year time sequence inhalation toxicity study of vinyl chloride in rats. I. Growth, mortality, haematology, clinical chemistry and organ weights. Feron, V.J., Kruysse, A., Til, H.P. Toxicology (1979) [Pubmed]
  13. Chemical analysis of gallstones. Steen, G., Blijenberg, B.G. European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies. (1991) [Pubmed]
  14. Developmental toxicity of L-selenomethionine in Macaca fascicularis. Tarantal, A.F., Willhite, C.C., Lasley, B.L., Murphy, C.J., Miller, C.J., Cukierski, M.J., Book, S.A., Hendrickx, A.G. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1991) [Pubmed]
  15. Levonorgestrel implants (Norplant II) for male contraception clinical trials: combination with transdermal and injectable testosterone. Gonzalo, I.T., Swerdloff, R.S., Nelson, A.L., Clevenger, B., Garcia, R., Berman, N., Wang, C. J. Clin. Endocrinol. Metab. (2002) [Pubmed]
  16. Hypercholesterolemia in ENU-induced mouse mutants. Mohr, M., Klempt, M., Rathkolb, B., de Angelis, M.H., Wolf, E., Aigner, B. J. Lipid Res. (2004) [Pubmed]
  17. Olestra dose response on fat-soluble and water-soluble nutrients in the pig. Cooper, D.A., Berry, D.A., Spendel, V.A., King, D., Kiorpes, A.L., Peters, J.C. J. Nutr. (1997) [Pubmed]
  18. Treatment of male hypogonadism with testosterone undecanoate injected at extended intervals of 12 weeks: a phase II study. von Eckardstein, S., Nieschlag, E. J. Androl. (2002) [Pubmed]
  19. Toxicology of aflatoxin B1, warfarin, and cadmium in young pigs: clinical chemistry and blood coagulation. Osuna, O., Edds, G.T. Am. J. Vet. Res. (1982) [Pubmed]
  20. Red blood cell electrolytes for monitoring digoxin therapy in adults. van Boxtel, C.J., Koopmans, R., Oosterhuis, B., Hoek, F.J. Therapeutic drug monitoring. (1985) [Pubmed]
  21. International Federation of Clinical Chemistry. Committee on Standards. Expert Panel on Enzymes. Approved recommendation (1978) on IFCC methods for the measurement of catalytic concentration of enzymes. Part 1. General considerations concerning the determination of the catalytic concentration of an enzyme in the blood serum or plasma of man. Bowers, G.N., Bergmeyer, H.U., Hørder, M., Moss, D.W. Clin. Chim. Acta (1979) [Pubmed]
  22. A subchronic toxicity study of Rokanol B-2 in rats. Krysiak, B., Rydzyński, K., Stetkiewicz, J., Stetkiewicz, I. International journal of occupational medicine and environmental health. (1996) [Pubmed]
  23. Standardization activities of markers of cardiac damage: the need of a comprehensive approach. Panteghini, M. Eur. Heart J. (1998) [Pubmed]
  24. Noneffect of oral urinary copper ascorbic acid on reduction glucose test. Nahata, M.C., McLeod, D.C. Diabetes Care (1978) [Pubmed]
  25. Physiological and clinical chemistry of biopterin. Nagatsu, T., Matsuura, S., Sugimoto, T. Medicinal research reviews. (1989) [Pubmed]
  26. Clinical implications of differences between two recommended procedures for determination of aspartate aminotransferase. Dols, J.L., van Zanten, A.P. Clin. Chem. (1983) [Pubmed]
  27. Modification of fully automated total iron-binding capacity (TIBC) assay in serum and comparison with dimension TIBC method. Yamanishi, H., Iyama, S., Yamaguchi, Y., Kanakura, Y., Iwatani, Y. Clin. Chem. (2002) [Pubmed]
  28. Suppression and transient induction of lymphokines in cancer patients after administration of polyethylene glycolated interleukin-2. Shih, Y., Konrad, M.W., Warren, M.K., Childs, A., Paradise, C., Meyers, F.J., Groves, E.S. Eur. J. Immunol. (1992) [Pubmed]
  29. Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin. Meier, U., Gressner, A.M. Clin. Chem. (2004) [Pubmed]
  30. Mid-molecule parathyroid hormone assay comparison. Ivie, W.M., Orwoll, E.S., McClung, M.R., Kenny, T.A., Swanson, J.R. Clin. Biochem. (1986) [Pubmed]
  31. Epitope analysis of a prostate-specific antigen (PSA) C-terminal-specific monoclonal antibody and new aspects for the discrepancy between equimolar and skewed PSA assays. Nagasaki, H., Watanabe, M., Komatsu, N., Kaneko, T., Dubé, J.Y., Kajita, T., Saitoh, Y., Ohta, Y. Clin. Chem. (1999) [Pubmed]
  32. Morphologic and molecular changes induced by recombinant human leptin in the white and brown adipose tissues of C57BL/6 mice. Sarmiento, U., Benson, B., Kaufman, S., Ross, L., Qi, M., Scully, S., DiPalma, C. Lab. Invest. (1997) [Pubmed]
  33. Automated homogeneous immunoassay for gentamicin on the dimension clinical chemistry system. Wei, T.Q., Chu, V.P., Craig, A.R., Duffy, J.E., Obzansky, D.M., Kilgore, D., Masulli, I.S., Sanders, C.M., Thompson, J.C. Clin. Chem. (1999) [Pubmed]
  34. Effects of intravenous infusion of ascorbate on common clinical chemistry tests. Badrick, T.C., Campbell, B. Clin. Chem. (1992) [Pubmed]
  35. Multicenter trial of the quantitative BTA TRAK assay in the detection of bladder cancer. Thomas, L., Leyh, H., Marberger, M., Bombardieri, E., Bassi, P., Pagano, F., Pansadoro, V., Sternberg, C.N., Boccon-Gibod, L., Ravery, V., Le Guludec, D., Meulemans, A., Conort, P., Ishak, L. Clin. Chem. (1999) [Pubmed]
  36. A placebo-controlled evaluation of single, escalating doses of CL 284,846, a non-benzodiazepine hypnotic. Beer, B., Ieni, J.R., Wu, W.H., Clody, D., Amorusi, P., Rose, J., Mant, T., Gaudreault, J., Cato, A., Stern, W. Journal of clinical pharmacology. (1994) [Pubmed]
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