Gene Review:
Klra1 - killer cell lectin-like receptor,...
Mus musculus
Synonyms:
A1, CH29-493D4.3, Klra22, Ly-49, Ly-49a, ...
- Critical Residues at the Ly49 Natural Killer Receptor's Homodimer Interface Determine Functional Recognition of m157, a Mouse Cytomegalovirus MHC Class I-Like Protein. Kielczewska, A., Kim, H.S., Lanier, L.L., Dimasi, N., Vidal, S.M. J. Immunol. (2007)
- The lymphoproliferative defect in CTLA-4-deficient mice is ameliorated by an inhibitory NK cell receptor. Chambers, C.A., Kang, J., Wu, Y., Held, W., Raulet, D.H., Allison, J.P. Blood (2002)
- Impaired anti-viral T cell responses due to expression of the Ly49A inhibitory receptor. Zajac, A.J., Vance, R.E., Held, W., Sourdive, D.J., Altman, J.D., Raulet, D.H., Ahmed, R. J. Immunol. (1999)
- Heterogeneous nuclear ribonucleoprotein A1 regulates RNA synthesis of a cytoplasmic virus. Shi, S.T., Huang, P., Li, H.P., Lai, M.M. EMBO J. (2000)
- The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5' splice site selection in vivo. Yang, X., Bani, M.R., Lu, S.J., Rowan, S., Ben-David, Y., Chabot, B. Proc. Natl. Acad. Sci. U.S.A. (1994)
- The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: the NK gene complex. Yokoyama, W.M., Seaman, W.E. Annu. Rev. Immunol. (1993)
- Crystal structure of a lectin-like natural killer cell receptor bound to its MHC class I ligand. Tormo, J., Natarajan, K., Margulies, D.H., Mariuzza, R.A. Nature (1999)
- Allelic exclusion of Ly49-family genes encoding class I MHC-specific receptors on NK cells. Held, W., Roland, J., Raulet, D.H. Nature (1995)
- Evidence for epigenetic maintenance of Ly49a monoallelic gene expression. Rouhi, A., Gagnier, L., Takei, F., Mager, D.L. J. Immunol. (2006)
- Class I MHC-binding characteristics of the 129/J Ly49 repertoire. Makrigiannis, A.P., Pau, A.T., Saleh, A., Winkler-Pickett, R., Ortaldo, J.R., Anderson, S.K. J. Immunol. (2001)
- Chromosomal location of the Ly-49 (A1, YE1/48) multigene family. Genetic association with the NK 1.1 antigen. Yokoyama, W.M., Kehn, P.J., Cohen, D.I., Shevach, E.M. J. Immunol. (1990)
- Thymus-dependent modulation of Ly49 inhibitory receptor expression on NK1.1+gamma/delta T cells. Hara, T., Nishimura, H., Hasegawa, Y., Yoshikai, Y. Immunology (2001)
- Transgenic expression of the Ly49A natural killer cell receptor confers class I major histocompatibility complex (MHC)-specific inhibition and prevents bone marrow allograft rejection. Held, W., Cado, D., Raulet, D.H. J. Exp. Med. (1996)
- Cloning and characterization of a novel activating Ly49 closely related to Ly49A. Makrigiannis, A.P., Gosselin, P., Mason, L.H., Taylor, L.S., McVicar, D.W., Ortaldo, J.R., Anderson, S.K. J. Immunol. (1999)
- The involvement of herpes simplex virus type 1 glycoproteins in cell-mediated immunity. Carter, V.C., Schaffer, P.A., Tevethia, S.S. J. Immunol. (1981)
- Cross-species dependence of ly49 recognition on the supertype defining B-pocket of a class I MHC molecule. Lavender, K.J., Kane, K.P. J. Immunol. (2006)
- Biochemical characterization of hamster oviductin as a sulphated zona pellucida-binding glycoprotein. Malette, B., Bleau, G. Biochem. J. (1993)
- H-2Dd engagement of Ly49A leads directly to Ly49A phosphorylation and recruitment of SHP1. Daws, M.R., Eriksson, M., Oberg, L., Ullén, A., Sentman, C.L. Immunology (1999)
- Heterogeneity among Ly-49C natural killer (NK) cells: characterization of highly related receptors with differing functions and expression patterns. Brennan, J., Lemieux, S., Freeman, J.D., Mager, D.L., Takei, F. J. Exp. Med. (1996)
- Interactions of Ly49 Family Receptors with MHC Class I Ligands in trans and cis. Scarpellino, L., Oeschger, F., Guillaume, P., Coudert, J.D., Lévy, F., Leclercq, G., Held, W. J. Immunol. (2007)
- Cutting edge: Ly49A inhibits TCR/CD3-induced apoptosis and IL-2 secretion. Roger, J., Chalifour, A., Lemieux, S., Duplay, P. J. Immunol. (2001)
- Arrested natural killer cell development associated with transgene insertion into the Atf2 locus. Kim, S., Song, Y.J., Higuchi, D.A., Kang, H.P., Pratt, J.R., Yang, L., Hong, C.M., Poursine-Laurent, J., Iizuka, K., French, A.R., Sunwoo, J.B., Ishii, S., Reimold, A.M., Yokoyama, W.M. Blood (2006)
- ATF-2-binding regulatory element is responsible for the Ly49A expression in murine T lymphoid line, EL-4. Kubo, S., Nagasawa, R., Nishimura, H., Shigemoto, K., Maruyama, N. Biochim. Biophys. Acta (1999)
- A role for the src family kinase Fyn in NK cell activation and the formation of the repertoire of Ly49 receptors. Lowin-Kropf, B., Kunz, B., Schneider, P., Held, W. Eur. J. Immunol. (2002)
- Cloning and functional characteristics of murine large granular lymphocyte-1: a member of the Ly-49 gene family (Ly-49G2). Mason, L.H., Ortaldo, J.R., Young, H.A., Kumar, V., Bennett, M., Anderson, S.K. J. Exp. Med. (1995)
- Ly-49 multigene family expressed by IL-2-activated NK cells. Smith, H.R., Karlhofer, F.M., Yokoyama, W.M. J. Immunol. (1994)
- Receptor/ligand avidity determines the capacity of Ly49 inhibitory receptors to interfere with T-cell receptor-mediated activation. Chalifour, A., Roger, J., Lemieux, S., Duplay, P. Immunology (2003)
- Crystal structure of the Ly49I natural killer cell receptor reveals variability in dimerization mode within the Ly49 family. Dimasi, N., Sawicki, M.W., Reineck, L.A., Li, Y., Natarajan, K., Margulies, D.H., Mariuzza, R.A. J. Mol. Biol. (2002)
- NKG2D receptor-mediated NK cell function is regulated by inhibitory Ly49 receptors. Regunathan, J., Chen, Y., Wang, D., Malarkannan, S. Blood (2005)
- Ly49A allelic variation and MHC class I specificity. Mehta, I.K., Wang, J., Roland, J., Margulies, D.H., Yokoyama, W.M. Immunogenetics (2001)
- External and internal calibration of the MHC class I-specific receptor Ly49A on murine natural killer cells. Kåse, A., Johansson, M.H., Olsson-Alheim, M.Y., Kärre, K., Höglund, P. J. Immunol. (1998)
- MHC class I expression protects target cells from lysis by Ly49-deficient fetal NK cells. Toomey, J.A., Shrestha, S., de la Rue, S.A., Gays, F., Robinson, J.H., Chrzanowska-Lightowlers, Z.M., Brooks, C.G. Eur. J. Immunol. (1998)
- Role of interaction between Ly49 inhibitory receptors and cognate MHC I molecules in IL2-induced development of NK cells in murine bone marrow cell cultures. Das, A., Saxena, R.K. Immunol. Lett. (2004)
- Characterization of the Ly49I promoter. Gosselin, P., Makrigiannis, A.P., Nalewaik, R., Anderson, S.K. Immunogenetics (2000)