Gene Review:
Tnfrsf10b - tumor necrosis factor receptor superfamily...
Mus musculus
Synonyms:
DR5, Death receptor 5, Dr5, KILLER, Killer, ...
- Induction of tumor-specific T cell immunity by anti-DR5 antibody therapy. Takeda, K., Yamaguchi, N., Akiba, H., Kojima, Y., Hayakawa, Y., Tanner, J.E., Sayers, T.J., Seki, N., Okumura, K., Yagita, H., Smyth, M.J. J. Exp. Med. (2004)
- Inducible silencing of KILLER/DR5 in vivo promotes bioluminescent colon tumor xenograft growth and confers resistance to chemotherapeutic agent 5-fluorouracil. Wang, S., El-Deiry, W.S. Cancer Res. (2004)
- The sequential treatment with ionizing radiation followed by TRAIL/Apo-2L reduces tumor growth and induces apoptosis of breast tumor xenografts in nude mice. Shankar, S., Singh, T.R., Chen, X., Thakkar, H., Firnin, J., Srivastava, R.K. Int. J. Oncol. (2004)
- Tumor-infiltrating CD4+ T lymphocytes express APO2 ligand (APO2L)/TRAIL upon specific stimulation with autologous lung carcinoma cells: role of IFN-alpha on APO2L/TRAIL expression and -mediated cytotoxicity. Dorothée, G., Vergnon, I., Menez, J., Echchakir, H., Grunenwald, D., Kubin, M., Chouaib, S., Mami-Chouaib, F. J. Immunol. (2002)
- Eradication of established tumors in mice by a combination antibody-based therapy. Uno, T., Takeda, K., Kojima, Y., Yoshizawa, H., Akiba, H., Mittler, R.S., Gejyo, F., Okumura, K., Yagita, H., Smyth, M.J. Nat. Med. (2006)
- Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Ichikawa, K., Liu, W., Zhao, L., Wang, Z., Liu, D., Ohtsuka, T., Zhang, H., Mountz, J.D., Koopman, W.J., Kimberly, R.P., Zhou, T. Nat. Med. (2001)
- An autosomal dominant locus, Nka, mapping to the Ly-49 region of a rat natural killer (NK) gene complex, controls NK cell lysis of allogeneic lymphocytes. Dissen, E., Ryan, J.C., Seaman, W.E., Fossum, S. J. Exp. Med. (1996)
- Retinoic acid-responsive enhancers located 3' of the Hox A and Hox B homeobox gene clusters. Functional analysis. Langston, A.W., Thompson, J.R., Gudas, L.J. J. Biol. Chem. (1997)
- Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model. Buchsbaum, D.J., Zhou, T., Grizzle, W.E., Oliver, P.G., Hammond, C.J., Zhang, S., Carpenter, M., LoBuglio, A.F. Clin. Cancer Res. (2003)
- Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor. Wu, G.S., Burns, T.F., Zhan, Y., Alnemri, E.S., El-Deiry, W.S. Cancer Res. (1999)
- DR5 knockout mice are compromised in radiation-induced apoptosis. Finnberg, N., Gruber, J.J., Fei, P., Rudolph, D., Bric, A., Kim, S.H., Burns, T.F., Ajuha, H., Page, R., Wu, G.S., Chen, Y., McKenna, W.G., Bernhard, E., Lowe, S., Mak, T., El-Deiry, W.S. Mol. Cell. Biol. (2005)
- Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Chinnaiyan, A.M., Prasad, U., Shankar, S., Hamstra, D.A., Shanaiah, M., Chenevert, T.L., Ross, B.D., Rehemtulla, A. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Promoter of TRAIL-R2 gene. Yoshida, T., Sakai, T. Vitam. Horm. (2004)
- TRAIL and KILLER are expressed and induce apoptosis in the murine preimplantation embryo. Riley, J.K., Heeley, J.M., Wyman, A.H., Schlichting, E.L., Moley, K.H. Biol. Reprod. (2004)
- TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Hao, C., Song, J.H., Hsi, B., Lewis, J., Song, D.K., Petruk, K.C., Tyrrell, D.L., Kneteman, N.M. Cancer Res. (2004)
- Cyclooxygenase-2 inhibitor and interferon-beta synergistically induce apoptosis in human hepatoma cells in vitro and in vivo. Nakamoto, N., Higuchi, H., Kanamori, H., Kurita, S., Tada, S., Takaishi, H., Toda, K., Yamada, T., Kumagai, N., Saito, H., Hibi, T. Int. J. Oncol. (2006)
- TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications. Mitsiades, C.S., Treon, S.P., Mitsiades, N., Shima, Y., Richardson, P., Schlossman, R., Hideshima, T., Anderson, K.C. Blood (2001)
- Uterine natural killer cells do not require interleukin-2 for their differentiation or maturation. Croy, B.A., Guimond, M.J., Luross, J., Hahnel, A., Wang, B., van den Heuvel, M. Am. J. Reprod. Immunol. (1997)
- Expression of Fas system-related genes in the testis during development and after toxicant exposure. Boekelheide, K., Lee, J., Shipp, E.B., Richburg, J.H., Li, G. Toxicol. Lett. (1998)
- Interrelationships among brain, endocrine and immune response in ageing and successful ageing: role of metallothionein III isoform. Giacconi, R., Cipriano, C., Muzzioli, M., Gasparini, N., Orlando, F., Mocchegiani, E. Mech. Ageing Dev. (2003)
- Interleukin-12 is not essential for silicosis in mice. Davis, G.S., Pfeiffer, L.M., Hemenway, D.R., Rincon, M. Particle and fibre toxicology [electronic resource]. (2006)
- Enhanced apoptosis and tumor regression induced by a direct agonist antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2. Motoki, K., Mori, E., Matsumoto, A., Thomas, M., Tomura, T., Humphreys, R., Albert, V., Muto, M., Yoshida, H., Aoki, M., Tamada, T., Kuroki, R., Yoshida, H., Ishida, I., Ware, C.F., Kataoka, S. Clin. Cancer Res. (2005)
- Analysis by sequential immunoprecipitations of the specificities of the monoclonal antibodies TU22,34,35,36,37,39,43,58 and YD1/63.HLK directed against human HLA class II antigens. Ziegler, A., Heinig, J., Müller, C., Götz, H., Thinnes, F.P., Uchańska-Ziegler, B., Wernet, P. Immunobiology (1986)
- Analysis of TRAIL receptor expression using anti-TRAIL death receptor-5 monoclonal antibodies. Ma, Y., Yang, D., Chen, Y. Chin. Med. J. (2003)