Gene Review:
Npy4r - neuropeptide Y receptor Y4
Mus musculus
Synonyms:
NPY4-R, NPYR-D, NYYR-D, Neuropeptide Y receptor type 4, PP1, ...
- Y4 receptor knockout rescues fertility in ob/ob mice. Sainsbury, A., Schwarzer, C., Couzens, M., Jenkins, A., Oakes, S.R., Ormandy, C.J., Herzog, H. Genes Dev. (2002)
- Synergistic effects of Y2 and Y4 receptors on adiposity and bone mass revealed in double knockout mice. Sainsbury, A., Baldock, P.A., Schwarzer, C., Ueno, N., Enriquez, R.F., Couzens, M., Inui, A., Herzog, H., Gardiner, E.M. Mol. Cell. Biol. (2003)
- Signal therapy of human pancreatic cancer and NF1-deficient breast cancer xenograft in mice by a combination of PP1 and GL-2003, anti-PAK1 drugs (Tyr-kinase inhibitors). Hirokawa, Y., Levitzki, A., Lessene, G., Baell, J., Xiao, Y., Zhu, H., Maruta, H. Cancer Lett. (2007)
- Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits. Mattingly, R.R., Macara, I.G. Nature (1996)
- Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis. Grishin, A.V., Azhipa, O., Semenov, I., Corey, S.J. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Phosphorylation-dependent targeting of cAMP response element binding protein to the ubiquitin/proteasome pathway in hypoxia. Taylor, C.T., Furuta, G.T., Synnestvedt, K., Colgan, S.P. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Regulation of collagenolytic protease secretion through c-Src in osteoclasts. Furuyama, N., Fujisawa, Y. Biochem. Biophys. Res. Commun. (2000)
- Comparison of protein phosphatase inhibition activities and mouse toxicities of microcystins. Chen, Y.M., Lee, T.H., Lee, S.J., Huang, H.B., Huang, R., Chou, H.N. Toxicon (2006)
- Monitoring of microcystin-protein phosphatase adduct formation with immunochemical methods. Liu, B.H., Yu, F.Y., Huang, X., Chu, F.S. Toxicon (2000)
- Cardiac function in neuropeptide Y Y4 receptor-knockout mice. Smith-White, M.A., Herzog, H., Potter, E.K. Regul. Pept. (2002)
- Lyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitors. Lannutti, B.J., Drachman, J.G. Blood (2004)
- Ultrarapid caspase-3 dependent apoptosis induction by serine/threonine phosphatase inhibitors. Fladmark, K.E., Brustugun, O.T., Hovland, R., Boe, R., Gjertsen, B.T., Zhivotovsky, B., Døskeland, S.O. Cell Death Differ. (1999)
- Y2Y4 receptor double knockout protects against obesity due to a high-fat diet or Y1 receptor deficiency in mice. Sainsbury, A., Bergen, H.T., Boey, D., Bamming, D., Cooney, G.J., Lin, S., Couzens, M., Stroth, N., Lee, N.J., Lindner, D., Singewald, N., Karl, T., Duffy, L., Enriquez, R., Slack, K., Sperk, G., Herzog, H. Diabetes (2006)
- Species differences in the expression and distribution of the neuropeptide Y Y1, Y2, Y4, and Y5 receptors in rodents, guinea pig, and primates brains. Dumont, Y., Jacques, D., Bouchard, P., Quirion, R. J. Comp. Neurol. (1998)
- Cloning and characterization of a novel receptor to pancreatic polypeptide, a member of the neuropeptide Y receptor family. Gregor, P., Millham, M.L., Feng, Y., DeCarr, L.B., McCaleb, M.L., Cornfield, L.J. FEBS Lett. (1996)
- Temporal and spatial expression of tissue inhibitors of metalloproteinases during the natural ovulatory cycle of the mouse. Inderdeo, D.S., Edwards, D.R., Han, V.K., Khokha, R. Biol. Reprod. (1996)
- Endogenous neuropeptide Y depresses the afferent signaling of gastric acid challenge to the mouse brainstem via neuropeptide Y type Y2 and Y4 receptors. Wultsch, T., Painsipp, E., Thoeringer, C.K., Herzog, H., Sperk, G., Holzer, P. Neuroscience (2005)
- Modulation of human estrogen receptor alpha F promoter by a protein kinase C/c-Src-dependent mechanism in osteoblast-like cells. Longo, M., Peruzzi, B., Fortunati, D., De Luca, V., Denger, S., Caselli, G., Migliaccio, S., Teti, A. J. Mol. Endocrinol. (2006)
- Differential reelin-induced enhancement of NMDA and AMPA receptor activity in the adult hippocampus. Qiu, S., Zhao, L.F., Korwek, K.M., Weeber, E.J. J. Neurosci. (2006)
- Mechanisms of neuropeptide Y, peptide YY, and pancreatic polypeptide inhibition of identified green fluorescent protein-expressing GABA neurons in the hypothalamic neuroendocrine arcuate nucleus. Acuna-Goycolea, C., Tamamaki, N., Yanagawa, Y., Obata, K., van den Pol, A.N. J. Neurosci. (2005)
- Role of P-selectin, beta2-integrins, and Src tyrosine kinases in mouse neutrophil-platelet adhesion. Evangelista, V., Manarini, S., Coller, B.S., Smyth, S.S. J. Thromb. Haemost. (2003)
- Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the SRC family kinase Hck. Zhou, H.R., Jia, Q., Pestka, J.J. Toxicol. Sci. (2005)
- Identification and distribution of mRNA encoding the Y1, Y2, Y4, and Y5 receptors for peptides of the PP-fold family in the rat intestine and colon. Goumain, M., Voisin, T., Lorinet, A.M., Laburthe, M. Biochem. Biophys. Res. Commun. (1998)
- Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase. Kwon, Y.G., Lee, S.Y., Choi, Y., Greengard, P., Nairn, A.C. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Protein serine/threonine phosphatase-1 dephosphorylates p53 at Ser-15 and Ser-37 to modulate its transcriptional and apoptotic activities. Li, D.W., Liu, J.P., Schmid, P.C., Schlosser, R., Feng, H., Liu, W.B., Yan, Q., Gong, L., Sun, S.M., Deng, M., Liu, Y. Oncogene (2006)