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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Goats

 
 
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Disease relevance of Goats

 

High impact information on Goats

  • Infection of goat synovial membrane (GSM) cells by caprine arthritis-encephalitis virus (CAEV) was inhibited by incubation of cells with CAEV gp 135 envelope glycoprotein (SU) expressed by recombinant vaccinia virus [6].
  • Precipitin lines formed between serum from a goat infected with caprine arthritis-encephalitis virus (CAEV) and radiolabelled viral proteins in polyethylene glycol-concentrated culture medium were excised from immunodiffusion (ID) plates and analysed by polyacrylamide gel electrophoresis [7].
  • In this report, we describe a short peptide, containing a T helper- and a B-cell epitope, located in the Gag protein of the caprine arthritis encephalitis virus (CAEV) [8].
  • SRY promoter of Shiba goat (Capra hircus var Shiba), a native Japanese miniature goat, showed the tissue-specific activity in the cells from urogenital ridges of the male mouse, but not in the cells from female mice, indicating a possibly different mechanism among species in the regulation of Sry expression [9].
  • The myostatin coding sequence was determined from duiker (Sylvicapra grimmia caffra), eland (Taurotragus derbianus), gaur (Bos gaurus), ibex (Capra ibex), impala (Aepyceros melampus rednilis), pronghorn (Antilocapra americana), and tahr (Hemitragus jemlahicus) [10].
 

Chemical compound and disease context of Goats

 

Biological context of Goats

 

Anatomical context of Goats

 

Associations of Goats with chemical compounds

  • The distribution of caprine leucocyte antigens (CLA) in goats from four different breeds (n = 546) affected by caprine arthritis-encephalitis virus (CAEV)-induced arthritis were determined and compared breed for breed with those of infected but clinically healthy controls (n = 402) [24].
  • Four Saanen goats were immunized with affinity purified gp135 surface glycoprotein (SU) of caprine arthritis-encephalitis virus isolate 79-63 (CAEV-63) and evaluated for homologous and crossreactive serum neutralizing antibodies [25].
  • Effects of oxytocin and an oxytocin antagonist on testosterone secretion during the oestrous cycle of the goat (Capra hircus) [26].
  • Abolition of the seasonal release of luteinizing hormone and testosterone in Alpine male goats (Capra hircus) by short photoperiodic cycles [27].
  • Photoperiod induction of fertile oestrus and changes in LH and progesterone concentrations in yearling dairy goats (Capra hircus) [28].
 

Gene context of Goats

  • CONCLUSION: Therefore, along with the caprine CD18-encoding cDNA, which has been available for a few months, the sequence data revealed here will allow the Capra hircus LFA-1 expression in vitro as a tool to explore the specificities of inflammation in the caprine species [22].
  • Experiments with several MAD and MIR electron-density maps of 2.4-2.8 A resolution reveal that CAPRA is capable of building approximately 90% of the backbone of a protein molecule, with an r.m.s. error for Calpha coordinates of around 0.9 A [29].
  • The COII gene was sequenced in representatives of three bovine tribes (Bovini, Boselaphini, and Tragelaphini) and the outgroup taxon Capra (subfamily Caprinae) [30].
  • The complete variable region sequences of 10K44-7A1 and 10K26-12A1 light chains were established based on the sequence analysis of tryptic peptides, intact light chains and reference sequences obtained previously [Siegelman M. and Capra, J.D. (1981) Proc. Natl Acad. Sci. USA, 78, 7679-7683] [31].
  • We have studied the expression of the inducible form of nitric oxide synthase (iNOS) in joints of goats infected with the caprine arthritis encephalitis virus (CAEV) [32].
 

Analytical, diagnostic and therapeutic context of Goats

References

  1. STAT1 pathway is involved in activation of caprine arthritis-encephalitis virus long terminal repeat in monocytes. Sepp, T., Tong-Starksen, S.E. J. Virol. (1997) [Pubmed]
  2. Maedi-visna virus and caprine arthritis encephalitis virus genomes encode a Vpr-like but no Tat protein. Villet, S., Bouzar, B.A., Morin, T., Verdier, G., Legras, C., Chebloune, Y. J. Virol. (2003) [Pubmed]
  3. Characterization of the caprine (Capra hircus) beta-2 integrin CD18-encoding cDNA and identification of mutations potentially responsible for the ruminant-specific virulence of Mannheimia haemolytica. Zecchinon, L., Fett, T., Baise, E., Desmecht, D. Mol. Membr. Biol. (2004) [Pubmed]
  4. A Rev protein is expressed in caprine arthritis encephalitis virus (CAEV)-infected cells and is required for efficient viral replication. Schoborg, R.V., Saltarelli, M.J., Clements, J.E. Virology (1994) [Pubmed]
  5. Cloning and expression of caprine interferon-gamma. Beyer, J.C., Stich, R.W., Hoover, D.S., Brown, W.C., Cheevers, W.P. Gene (1998) [Pubmed]
  6. Caprine arthritis-encephalitis lentivirus SU is the ligand for infection of caprine synovial membrane cells. Hullinger, G.A., Knowles, D.P., McGuire, T.C., Cheevers, W.P. Virology (1993) [Pubmed]
  7. Identification of caprine arthritis-encephalitis retrovirus proteins in immunodiffusion precipitin lines. Adams, D.S., Gogolewski, R.P., Barbet, A.F., Cheevers, W.P. J. Gen. Virol. (1985) [Pubmed]
  8. The MHC-haplotype influences primary, but not memory, immune responses to an immunodominant peptide containing T- and B-cell epitopes of the caprine arthritis encephalitis virus Gag protein. Fluri, A., Nenci, C., Zahno, M.L., Vogt, H.R., Charan, S., Busato, A., Pancino, G., Peterhans, E., Obexer-Ruff, G., Bertoni, G. Vaccine (2006) [Pubmed]
  9. Detection of elements responsible for stage- and tissue-specific expression of mouse Sry using an in vitro Cre/loxP system. Ito, M., Yokouchi, K., Naito, K., Endo, H., Hakamata, Y., Miyazaki, J., Tojo, H. Biochem. Biophys. Res. Commun. (2005) [Pubmed]
  10. Myostatin rapid sequence evolution in ruminants predates domestication. Tellgren, A., Berglund, A.C., Savolainen, P., Janis, C.M., Liberles, D.A. Mol. Phylogenet. Evol. (2004) [Pubmed]
  11. Cytokine production in vitro by macrophages of goats with caprine arthritis-encephalitis. Adeyemo, O., Gao, R.J., Lan, H.C. Cell. Mol. Biol. (Noisy-le-grand) (1997) [Pubmed]
  12. Effect of dehydration on the pharmacokinetics of oxytetracycline hydrochloride administered intravenously in goats (Capra hircus). Elsheikh, H.A., Osman Intisar, A.M., Eltayeb, I.B., Salam Abdullah, A. Gen. Pharmacol. (1998) [Pubmed]
  13. Immunisation of goats against contagious caprine pleuropneumonia using sonicated antigens of F-38 strain of mycoplasma. Rurangirwa, F.R., Masiga, W.N., Muthomi, E.K. Res. Vet. Sci. (1984) [Pubmed]
  14. Evidence for prostaglandin involvement in early luteal regression of the superovulated nanny goat (Capra hircus). Battye, K.M., Fairclough, R.J., Cameron, A.W., Trounson, A.O. J. Reprod. Fertil. (1988) [Pubmed]
  15. Oestrogen concentrations in systemic plasma of pregnant pygmy goats. Dhindsa, D.S., Metcalfe, J., Resko, J.A. J. Reprod. Fertil. (1981) [Pubmed]
  16. Why fuse the mandibular symphysis? A comparative analysis. Lieberman, D.E., Crompton, A.W. Am. J. Phys. Anthropol. (2000) [Pubmed]
  17. Comparative pharmacokinetics of amikacin following a single intramuscular or subcutaneous administration in goats (Capra hircus). Uppal, R.P., Verma, S.P., Verma, V., Garg, S.K. Vet. Res. (1997) [Pubmed]
  18. Chromosomal localization of omega and trophoblast interferon genes in goat and sheep by fluorescent in situ hybridization. Iannuzzi, L., Di Meo, G.P., Gallagher, D.S., Ryan, A.M., Ferrara, L., Womack, J.E. J. Hered. (1993) [Pubmed]
  19. Histochemical studies on steroid dehydrogenases in the testis of the goat (Capra hircus). Bilaspuri, G.S., Guraya, S.S. J. Endocrinol. (1984) [Pubmed]
  20. Potent and stage-specific action of glutathione on the development of goat early embryos in vitro. Lee, C.S., Koo, D.B., Fang, N., Lee, Y., Shin, S.T., Park, C.S., Lee, K.K. Mol. Reprod. Dev. (2000) [Pubmed]
  21. Caprine arthritis encephalitis virus infection changes caprine blood monocyte responsiveness to lipopolysaccharide stimulation in vitro. Werling, D., Langhans, W., Geary, N. Vet. Immunol. Immunopathol. (1994) [Pubmed]
  22. Molecular characterisation of the caprine (Capra hircus) lymphocyte function-associated antigen-1 alpha subunit-encoding cDNA. Fett, T., Zecchinon, L.L., Baise, E.A., Desmecht, D.J. BMC Vet. Res. (2005) [Pubmed]
  23. Luteinizing hormone and follicle stimulating hormone induce premature condensation of chromatin in goat (Capra hircus) oocytes. Kumar, J., Osborn, J.C., Cameron, A.W. Reprod. Fertil. Dev. (1991) [Pubmed]
  24. Evidence for linkage between the caprine leucocyte antigen (CLA) system and susceptibility to CAE virus-induced arthritis in goats. Ruff, G., Lazary, S. Immunogenetics (1988) [Pubmed]
  25. Crossreactive neutralizing antibodies induced by immunization with caprine arthritis-encephalitis virus surface glycoprotein. Kemp, R.K., Knowles, D.P., Perry, L.L., McGuire, T.C., Besser, T.E., Cheevers, W.P. Vaccine (2000) [Pubmed]
  26. Effects of oxytocin and an oxytocin antagonist on testosterone secretion during the oestrous cycle of the goat (Capra hircus). Homeida, A.M., Khalafalla, A.E. J. Reprod. Fertil. (1990) [Pubmed]
  27. Abolition of the seasonal release of luteinizing hormone and testosterone in Alpine male goats (Capra hircus) by short photoperiodic cycles. Delgadillo, J.A., Chemineau, P. J. Reprod. Fertil. (1992) [Pubmed]
  28. Photoperiod induction of fertile oestrus and changes in LH and progesterone concentrations in yearling dairy goats (Capra hircus). BonDurant, R.H., Darien, B.J., Munro, C.J., Stabenfeldt, G.H., Wang, P. J. Reprod. Fertil. (1981) [Pubmed]
  29. Automatic modeling of protein backbones in electron-density maps via prediction of Calpha coordinates. Ioerger, T.R., Sacchettini, J.C. Acta Crystallogr. D Biol. Crystallogr. (2002) [Pubmed]
  30. Mitochondrial gene sequences and the molecular systematics of the artiodactyl subfamily bovinae. Janecek, L.L., Honeycutt, R.L., Adkins, R.M., Davis, S.K. Mol. Phylogenet. Evol. (1996) [Pubmed]
  31. A sensitive peptide mapping method. Identification of three amino acid substitutions within two anti-azobenzenearsonate monoclonal antibody light chains. Chang, J.Y., Knecht, R., Ball, R., Alkan, S.S., Braun, D.G. Eur. J. Biochem. (1982) [Pubmed]
  32. Inducible nitric oxide synthase is expressed in joints of goats in the late stage of infection with caprine arthritis encephalitis virus. Lechner, F., Schütte, A., Von Bodungen, U., Bertoni, G., Pfister, H., Jungi, T.W., Peterhans, E. Clin. Exp. Immunol. (1999) [Pubmed]
  33. Comparative FISH-mapping of villin (VIL) gene in river buffalo, sheep and goat chromosomes. Iannuzzi, L., Skow, L., Di Meo, G.P., Gallagher, D.S., Womack, J.E. Chromosome Res. (1997) [Pubmed]
  34. Pharmacokinetics of carfentanil and naltrexone in domestic goats (Capra hircus). Mutlow, A., Isaza, R., Carpenter, J.W., Koch, D.E., Hunter, R.P. J. Zoo Wildl. Med. (2004) [Pubmed]
  35. Immobilization of domestic goats (Capra hircus) using orally administered carfentanil citrate and detomidine hydrochloride. Sleeman, J.M., Carter, W., Tobin, T., Ramsay, E.C. J. Zoo Wildl. Med. (1997) [Pubmed]
 
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