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MeSH Review

Keratoplasty, Penetrating

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Disease relevance of Keratoplasty, Penetrating


High impact information on Keratoplasty, Penetrating


Chemical compound and disease context of Keratoplasty, Penetrating


Biological context of Keratoplasty, Penetrating


Anatomical context of Keratoplasty, Penetrating


Associations of Keratoplasty, Penetrating with chemical compounds


Gene context of Keratoplasty, Penetrating

  • Group I consisted of the 147 penetrating keratoplasties with up to 13 triplet-string mismatches (the typical upper limit of foreign in case of a single HLA-A or HLA-B allele mismatch) and was compared to the remaining 398 patients with more triplet mismatches (group II) using the Kaplan-Meier method and log-rank statistics [7].
  • PARTICIPANTS: Chart review of 73 patients (110 eyes) with recently confirmed BIGH3 mutations who underwent a penetrating keratoplasty (PK) from 1978 through 1999 [28].
  • OBJECTIVE: To test CD-34 immunoreactivity in stromal cornea cells in normal and pathologic samples obtained from penetrating keratoplasty [29].
  • METHODS: Penetrating keratoplasty specimens removed from 5 patients with HSK were divided to provide adjacent sections that were incubated with control medium or the same medium containing IL-10 (100 U/ml) for 48 hours [30].
  • OBJECTIVE: To review our experience using tPA to revive previously functional but newly failing blebs following secondary surgical procedures (cataract extraction or penetrating keratoplasty) [31].

Analytical, diagnostic and therapeutic context of Keratoplasty, Penetrating


  1. Increased expression of inflammatory cytokines and matrix metalloproteinases in pseudophakic corneal edema. Shoshani, Y., Pe'er, J., Doviner, V., Frucht-Pery, J., Solomon, A. Invest. Ophthalmol. Vis. Sci. (2005) [Pubmed]
  2. Laser in situ keratomileusis for correction of myopia and astigmatism after penetrating keratoplasty. Donnenfeld, E.D., Kornstein, H.S., Amin, A., Speaker, M.D., Seedor, J.A., Sforza, P.D., Landrio, L.M., Perry, H.D. Ophthalmology (1999) [Pubmed]
  3. Risk factors in microbial keratitis leading to penetrating keratoplasty. Miedziak, A.I., Miller, M.R., Rapuano, C.J., Laibson, P.R., Cohen, E.J. Ophthalmology (1999) [Pubmed]
  4. Acyclovir-resistant herpes simplex virus keratouveitis after penetrating keratoplasty. Sonkin, P.L., Baratz, K.H., Frothingham, R., Cobo, L.M. Ophthalmology (1992) [Pubmed]
  5. Timolol therapy in secondary angle-closure glaucoma post penetrating keratoplasty. Lass, J.H., Pavan-Langston, D. Ophthalmology (1979) [Pubmed]
  6. Adhesion structures of amniotic membranes integrated into human corneas. Resch, M.D., Schlötzer-Schrehardt, U., Hofmann-Rummelt, C., Sauer, R., Cursiefen, C., Kruse, F.E., Beckmann, M.W., Seitz, B. Invest. Ophthalmol. Vis. Sci. (2006) [Pubmed]
  7. Beneficial effect of matching at the HLA-A and -B amino-acid triplet level on rejection-free clear graft survival in penetrating keratoplasty. Böhringer, D., Reinhard, T., Duquesnoy, R.J., Böhringer, S., Enczmann, J., Lange, P., Claas, F., Sundmacher, R. Transplantation (2004) [Pubmed]
  8. Two mutations in the TGFBI (BIGH3) gene associated with lattice corneal dystrophy in an extensively studied family. Klintworth, G.K., Bao, W., Afshari, N.A. Invest. Ophthalmol. Vis. Sci. (2004) [Pubmed]
  9. Fate of MHC-matched corneal allografts in Th1-deficient hosts. Hargrave, S.L., Hay, C., Mellon, J., Mayhew, E., Niederkorn, J.Y. Invest. Ophthalmol. Vis. Sci. (2004) [Pubmed]
  10. Th2-biased immune system promotion of allogeneic corneal epithelial cell survival after orthotopic limbal transplantation. Maruyama, K., Yamada, J., Sano, Y., Kinoshita, S. Invest. Ophthalmol. Vis. Sci. (2003) [Pubmed]
  11. Keratitis caused by Scedosporium apiospermum successfully treated with a cornea transplant and voriconazole. Nulens, E., Eggink, C., Rijs, A.J., Wesseling, P., Verweij, P.E. J. Clin. Microbiol. (2003) [Pubmed]
  12. Gentamicin-resistant Pseudomonas endophthalmitis after penetrating keratoplasty. Insler, M.S., Cavanagh, H.D., Wilson, L.A. The British journal of ophthalmology. (1985) [Pubmed]
  13. Penetrating keratoplasty in Africa: graft survival and visual outcome. Yorston, D., Wood, M., Foster, A. The British journal of ophthalmology. (1996) [Pubmed]
  14. Evaluation of hematoxylin and eosin and special stains for the detection of acanthamoeba keratitis in penetrating keratoplasties. Grossniklaus, H.E., Waring, G.O., Akor, C., Castellano-Sanchez, A.A., Bennett, K. Am. J. Ophthalmol. (2003) [Pubmed]
  15. Corneal argon laser photocoagulation for neovascularization in penetrating keratoplasty. Nirankari, V.S., Baer, J.C. Ophthalmology (1986) [Pubmed]
  16. Phototherapeutic keratectomy for macular corneal dystrophy. Wagoner, M.D., Badr, I.A. Journal of refractive surgery (Thorofare, N.J. : 1995) (1999) [Pubmed]
  17. A study of glaucoma after penetrating keratoplasty. França, E.T., Arcieri, E.S., Arcieri, R.S., Rocha, F.J. Cornea (2002) [Pubmed]
  18. The effect of indomethacin on prostaglandin E2 in human cornea and conjunctiva. Frucht-Pery, J., Zauberman, H. Arch. Ophthalmol. (1992) [Pubmed]
  19. Low-dose intraocular tissue plasminogen activator treatment for traumatic total hyphema, postcataract, and penetrating keratoplasty fibrinous membranes. Starck, T., Hopp, L., Held, K.S., Marouf, L.M., Yee, R.W. Journal of cataract and refractive surgery. (1995) [Pubmed]
  20. Soluble Fas ligand and transforming growth factor beta2 in the aqueous humor of patients with endothelial immune reactions after penetrating keratoplasty. Reinhard, T., Bönig, H., Mayweg, S., Böhringer, D., Göbel, U., Sundmacher, R. Arch. Ophthalmol. (2002) [Pubmed]
  21. The behaviour of ED1- and ED2-positive cells in the rat iris and choroid following penetrating keratoplasty and cyclosporin A therapy. Krause, L., Coupland, S.E., Hoffmann, F. Graefes Arch. Clin. Exp. Ophthalmol. (1996) [Pubmed]
  22. Resolution of epithelial ingrowth in a patient treated with 5-fluorouracil. Lai, M.M., Haller, J.A. Am. J. Ophthalmol. (2002) [Pubmed]
  23. Corneal herpes simplex virus type 1 superinfection in patients with recrudescent herpetic keratitis. Remeijer, L., Maertzdorf, J., Buitenwerf, J., Osterhaus, A.D., Verjans, G.M. Invest. Ophthalmol. Vis. Sci. (2002) [Pubmed]
  24. Promotion of corneal allograft survival with leflunomide. Niederkorn, J.Y., Lang, L.S., Ross, J., Mellon, J., Robertson, S.M. Invest. Ophthalmol. Vis. Sci. (1994) [Pubmed]
  25. Effect of oral acyclovir after penetrating keratoplasty for herpetic keratitis: a placebo-controlled multicenter trial. van Rooij, J., Rijneveld, W.J., Remeijer, L., Völker-Dieben, H.J., Eggink, C.A., Geerards, A.J., Mulder, P.G., Doornenbal, P., Beekhuis, W.H. Ophthalmology (2003) [Pubmed]
  26. Corneal stromal penetration of topical ciprofloxacin in humans. McDermott, M.L., Tran, T.D., Cowden, J.W., Buggé, C.J. Ophthalmology (1993) [Pubmed]
  27. Survival of corneal grafts from donors supported by mechanical ventilation. Seedor, J.A., Stulting, R.D., Epstein, R.J., Nay, R.E., Dreizen, N.G., Waring, G.O., Wilson, L.A., Cavanagh, H.D. Ophthalmology (1987) [Pubmed]
  28. Clinical outcome of eight BIGH3-linked corneal dystrophies. Ellies, P., Renard, G., Valleix, S., Boelle, P.Y., Dighiero, P. Ophthalmology (2002) [Pubmed]
  29. CD-34 stromal expression pattern in normal and altered human corneas. Toti, P., Tosi, G.M., Traversi, C., Schürfeld, K., Cardone, C., Caporossi, A. Ophthalmology (2002) [Pubmed]
  30. Interleukin-10 inhibition of HLA-DR expression in human herpes stromal keratitis. Boorstein, S.M., Elner, S.G., Meyer, R.F., Sugar, A., Strieter, R.M., Kunkel, S.L., Elner, V.M. Ophthalmology (1994) [Pubmed]
  31. Use of tissue plasminogen activator to revive blebs following intraocular surgery. Smith, M.F., Doyle, J.W. Arch. Ophthalmol. (2001) [Pubmed]
  32. Lattice corneal dystrophy associated with familial systemic amyloidosis (Meretoja's syndrome). Purcell, J.J., Rodrigues, M., Chishti, M.I., Riner, R.N., Dooley, J.M. Ophthalmology (1983) [Pubmed]
  33. Granular corneal dystrophy. Visual results and pattern of recurrence after lamellar or penetrating keratoplasty. Lyons, C.J., McCartney, A.C., Kirkness, C.M., Ficker, L.A., Steele, A.D., Rice, N.S. Ophthalmology (1994) [Pubmed]
  34. Clinical uses of collagen shields. Poland, D.E., Kaufman, H.E. Journal of cataract and refractive surgery. (1988) [Pubmed]
  35. Photorefractive keratectomy for post-penetrating keratoplasty myopia and astigmatism. Bilgihan, K., Ozdek, S.C., Akata, F., Hasanreisoğlu, B. Journal of cataract and refractive surgery. (2000) [Pubmed]
  36. Oral acyclovir reduces the incidence of recurrent herpes simplex keratitis in rabbits after penetrating keratoplasty. Beyer, C.F., Arens, M.Q., Hill, G.A., Rose, B.T., Beyer, L.R., Schanzlin, D.J. Arch. Ophthalmol. (1989) [Pubmed]
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