The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

hypotaurine     2-aminoethanesulfinic acid

Synonyms: Lopac-H-1384, Tocris-0208, H1384_ALDRICH, ACMC-1CMF0, AG-E-98503, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of hypotaurine


High impact information on hypotaurine


Chemical compound and disease context of hypotaurine


Biological context of hypotaurine


Anatomical context of hypotaurine


Associations of hypotaurine with other chemical compounds


Gene context of hypotaurine


Analytical, diagnostic and therapeutic context of hypotaurine


  1. Taurine, hypotaurine, and GABA uptake by cultured neuroblastoma cells. Holopainen, I., Kontro, P., Frey, H.J., Oja, S.S. J. Neurosci. Res. (1983) [Pubmed]
  2. Production of hypotaurine, taurine and sulfate in rats and mice injected with L: -cysteinesulfinate. Nakamura, H., Yatsuki, J., Ubuka, T. Amino Acids (2006) [Pubmed]
  3. Role of taurine as a possible transmitter in the thermoregulatory pathways of the rat. Kerwin, R.W., Pycock, C.J. J. Pharm. Pharmacol. (1979) [Pubmed]
  4. UDP-N-acetylhexosamines and hypotaurine in human glioblastoma, normal brain tissue and cell cultures: 1H/NMR spectroscopy study. Sonnewald, U., Isern, E., Gribbestad, I.S., Unsgård, G. Anticancer Res. (1994) [Pubmed]
  5. Lectin-coated agarose beads in the investigation of sperm capacitation in the hamster. Ahuja, K.K. Dev. Biol. (1984) [Pubmed]
  6. Metabolism of cysteine in astroglial cells: synthesis of hypotaurine and taurine. Brand, A., Leibfritz, D., Hamprecht, B., Dringen, R. J. Neurochem. (1998) [Pubmed]
  7. Characteristics of taurine transport in rat liver lysosomes. Vadgama, J.V., Chang, K., Kopple, J.D., Idriss, J.M., Jonas, A.J. J. Cell. Physiol. (1991) [Pubmed]
  8. Taurine and hypotaurine content of human leukocytes. Learn, D.B., Fried, V.A., Thomas, E.L. J. Leukoc. Biol. (1990) [Pubmed]
  9. Metabolism of cysteine in rat hepatocytes. Evidence for cysteinesulphinate-independent pathways. Drake, M.R., De La Rosa, J., Stipanuk, M.H. Biochem. J. (1987) [Pubmed]
  10. Taurine and hypotaurine transport by a single system in cultured neuroblastoma cells. Holopainen, I., Kontro, P. Acta Physiol. Scand. (1984) [Pubmed]
  11. Accumulation of hypotaurine in tissues and urine of rats fed an excess methionine diet. Kasai, T., Ogo, Y., Otobe, Y., Kiriyama, S. J. Nutr. Sci. Vitaminol. (1992) [Pubmed]
  12. Taurine and hypotaurine dynamics in activated C6 glioma: the effects of lipopolysaccharide (LPS) and taurine administration on intracellular hypotaurine and taurine dynamics in C6 glioma. Dominy, J., Dawson, R. Adv. Exp. Med. Biol. (2003) [Pubmed]
  13. Taurine, hypotaurine, epinephrine and albumin inhibit lipid peroxidation in rabbit spermatozoa and protect against loss of motility. Alvarez, J.G., Storey, B.T. Biol. Reprod. (1983) [Pubmed]
  14. Effect of hypotaurine on in vitro fertilization and production of term offspring from in vitro-fertilized ova of the Japanese field vole, Microtus montebelli. Wakayama, T., Suto, J.I., Imamura, K., Toyoda, Y., Kurohmaru, M., Hayashi, Y. Biol. Reprod. (1996) [Pubmed]
  15. Hypotaurine requirement for in vitro development of golden hamster one-cell embryos into morulae and blastocysts, and production of term offspring from in vitro-fertilized ova. Barnett, D.K., Bavister, B.D. Biol. Reprod. (1992) [Pubmed]
  16. Addition of hypotaurine can reactivate immotile golden hamster spermatozoa. Boatman, D.E., Bavister, B.D., Cruz, E. J. Androl. (1990) [Pubmed]
  17. Hypotaurine in spermatozoa and genital secretions and its production by oviduct epithelial cells in vitro. Guérin, P., Guillaud, J., Ménézo, Y. Hum. Reprod. (1995) [Pubmed]
  18. Cation dependence of hypotaurine uptake in mouse brain slices. Kontro, P., Oja, S.S. J. Neurochem. (1981) [Pubmed]
  19. Stimulation of somatostatin release from median eminence tissue incubated in vitro by taurine and related amino acids. Aguila, M.C., McCann, S.M. Endocrinology (1985) [Pubmed]
  20. Hypotaurine uptake by the retina. Pasantes-Morales, H., Morán, J., Fellman, J.H. J. Neurosci. Res. (1986) [Pubmed]
  21. Nuclear magnetic resonance studies of boar seminal plasma. Problems encountered in the identification of small molecules: hypotaurine and carnitine. Kalic, M., Kamp, G., Lauterwein, J. NMR in biomedicine. (1997) [Pubmed]
  22. Roles of cysteine sulfinate and transaminase on in vitro dark reversion of urocanase in Pseudomonas putida. Hug, D.H., Hunter, J.K. J. Bacteriol. (1982) [Pubmed]
  23. Metabolism of cysteine and cysteinesulfinate in rat and cat hepatocytes. de la Rosa, J., Drake, M.R., Stipanuk, M.H. J. Nutr. (1987) [Pubmed]
  24. Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses. Yancey, P.H. J. Exp. Biol. (2005) [Pubmed]
  25. Identification of low-molecular-weight compounds in goat epididymis using multinuclear nuclear magnetic resonance. Patel, A.B., Srivastava, S., Phadke, R.S., Govil, G. Anal. Biochem. (1999) [Pubmed]
  26. Effects of sperm treatments on the in vitro development of bovine oocytes in semidefined and defined media. Jaakma, U., Zhang, B.R., Larsson, B., Niwa, K., Rodriguez-Martinez, H. Theriogenology (1997) [Pubmed]
  27. Analysis of the impact of intracellular reactive oxygen species generation on the structural and functional integrity of human spermatozoa: lipid peroxidation, DNA fragmentation and effectiveness of antioxidants. Twigg, J., Fulton, N., Gomez, E., Irvine, D.S., Aitken, R.J. Hum. Reprod. (1998) [Pubmed]
  28. Specificity of cysteine sulfinate decarboxylase (CSD) for sulfur-containing amino-acids. Do, K.Q., Tappaz, M.L. Neurochem. Int. (1996) [Pubmed]
  29. The taurine and hypotaurine content of human semen. Holmes, R.P., Goodman, H.O., Shihabi, Z.K., Jarow, J.P. J. Androl. (1992) [Pubmed]
  30. Determination of cysteinesulfinate, hypotaurine and taurine in physiological samples by reversed-phase high-performance liquid chromatography. Hirschberger, L.L., De La Rosa, J., Stipanuk, M.H. J. Chromatogr. (1985) [Pubmed]
  31. Formation and accumulation of hypotaurine in rat liver regenerating after partial hepatectomy. Sturman, J.A. Life Sci. (1980) [Pubmed]
  32. Isolation, culture and characteristics of epididymal epithelial cells from adult cats. Buff, S., Lambert, V., Marchal, T., Guérin, P. Theriogenology (2005) [Pubmed]
WikiGenes - Universities