The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

CHEMBL1160563     (2R)-2-hydroxy-3- phosphonooxy-propanoic acid

Synonyms: CHEBI:17794, bmse000007, CTK1B7705, AC1L96U5, C00197, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of 3PG


Psychiatry related information on 3PG


High impact information on 3PG


Chemical compound and disease context of 3PG


Biological context of 3PG


Anatomical context of 3PG


Associations of 3PG with other chemical compounds


Gene context of 3PG


Analytical, diagnostic and therapeutic context of 3PG


  1. Regulation of serine biosynthesis in Arabidopsis. Crucial role of plastidic 3-phosphoglycerate dehydrogenase in non-photosynthetic tissues. Ho, C.L., Noji, M., Saito, M., Saito, K. J. Biol. Chem. (1999) [Pubmed]
  2. Mechanism of catalysis of the cofactor-independent phosphoglycerate mutase from Bacillus stearothermophilus. Crystal structure of the complex with 2-phosphoglycerate. Jedrzejas, M.J., Chander, M., Setlow, P., Krishnasamy, G. J. Biol. Chem. (2000) [Pubmed]
  3. A transport system for phosphoenolpyruvate, 2-phosphoglycerate, and 3-phosphoglycerate in Salmonella typhimurium. Saier, M.H., Wentzel, D.L., Feucht, B.U., Judice, J.J. J. Biol. Chem. (1975) [Pubmed]
  4. Novel role of 3-phosphoglycerate kinase, a glycolytic enzyme, in the activation of L-nucleoside analogs, a new class of anticancer and antiviral agents. Krishnan, P., Gullen, E.A., Lam, W., Dutschman, G.E., Grill, S.P., Cheng, Y.C. J. Biol. Chem. (2003) [Pubmed]
  5. Evaluation of GAL4/TATA in vivo. Induction of transgene expression by adenovirally mediated gene codelivery. Fang, B., Ji, L., Bouvet, M., Roth, J.A. J. Biol. Chem. (1998) [Pubmed]
  6. Cerebral folate deficiency. Ramaekers, V.T., Blau, N. Developmental medicine and child neurology. (2004) [Pubmed]
  7. Synergistic effects of substrate-induced conformational changes in phosphoglycerate kinase activation. Bernstein, B.E., Michels, P.A., Hol, W.G. Nature (1997) [Pubmed]
  8. A rectifying ATP-regulated solute channel in the chloroplastic outer envelope from pea. Bölter, B., Soll, J., Hill, K., Hemmler, R., Wagner, R. EMBO J. (1999) [Pubmed]
  9. Molecular characterization of 3-phosphoglycerate dehydrogenase deficiency--a neurometabolic disorder associated with reduced L-serine biosynthesis. Klomp, L.W., de Koning, T.J., Malingré, H.E., van Beurden, E.A., Brink, M., Opdam, F.L., Duran, M., Jaeken, J., Pineda, M., Van Maldergem, L., Poll-The, B.T., van den Berg, I.E., Berger, R. Am. J. Hum. Genet. (2000) [Pubmed]
  10. Generation of up-regulated allosteric variants of potato ADP-glucose pyrophosphorylase by reversion genetics. Greene, T.W., Kavakli, I.H., Kahn, M.L., Okita, T.W. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  11. A recombinant bisphosphoglycerate mutase variant with acid phosphatase homology degrades 2,3-diphosphoglycerate. Garel, M.C., Arous, N., Calvin, M.C., Craescu, C.T., Rosa, J., Rosa, R. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
  12. A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria. Zhao, G., Winkler, M.E. J. Bacteriol. (1996) [Pubmed]
  13. Interaction between D-glyceraldehyde-3-phosphate dehydrogenase and 3-phosphoglycerate kinase and its functional consequences. Khoroshilova, N.A., Muronetz, V.I., Nagradova, N.K. FEBS Lett. (1992) [Pubmed]
  14. Ultrasensitive behavior in the synthesis of storage polysaccharides in cyanobacteria. Gómez-Casati, D.F., Cortassa, S., Aon, M.A., Iglesias, A.A. Planta (2003) [Pubmed]
  15. Red-edge excitation fluorescence measurements of several two-tryptophan-containing proteins. Wasylewski, Z., Kołoczek, H., Waśniowska, A., Slizowska, K. Eur. J. Biochem. (1992) [Pubmed]
  16. Amplification of maize ribulose bisphosphate carboxylase large subunit synthesis in E. coli by transcriptional fusion with the lambda N operon. Gatenby, A.A., Castleton, J.A. Mol. Gen. Genet. (1982) [Pubmed]
  17. 3-Phosphoglycerate-dependent protein phosphorylation. Ueda, T., Plagens, D.G. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  18. Gene for the ribulose-1,5-bisphosphate carboxylase small subunit protein of the marine chromophyte Olisthodiscus luteus is similar to that of a chemoautotrophic bacterium. Boczar, B.A., Delaney, T.P., Cattolico, R.A. Proc. Natl. Acad. Sci. U.S.A. (1989) [Pubmed]
  19. Biogenesis of glycosomes of Trypanosoma brucei: an in vitro model of 3-phosphoglycerate kinase import. Dovey, H.F., Parsons, M., Wang, C.C. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  20. Parental imprinting studied by allele-specific primer extension after PCR: paternal X chromosome-linked genes are transcribed prior to preferential paternal X chromosome inactivation. Singer-Sam, J., Chapman, V., LeBon, J.M., Riggs, A.D. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  21. Saccharomyces cerevisiae secretes and correctly processes human interferon hybrid proteins containing yeast invertase signal peptides. Chang, C.N., Matteucci, M., Perry, L.J., Wulf, J.J., Chen, C.Y., Hitzeman, R.A. Mol. Cell. Biol. (1986) [Pubmed]
  22. Single gene for the large subunit of ribulosebisphosphate carboxylase in maize yields two differentially regulated mRNAs. Crossland, L.D., Rodermel, S.R., Bogorad, L. Proc. Natl. Acad. Sci. U.S.A. (1984) [Pubmed]
  23. Protein phosphorylation in pancreatic islets induced by 3-phosphoglycerate and 2-phosphoglycerate. Pek, S.B., Usami, M., Bilir, N., Fischer-Bovenkerk, C., Ueda, T. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  24. Enzyme activities at the surface of intact Ehrlich tumor cells with albumin in the isotonic assay medium. Wernstedt, C.O., Agren, G.K., Ronquist, G. Cancer Res. (1975) [Pubmed]
  25. D-serine in the developing human central nervous system. Fuchs, S.A., Dorland, L., De Sain-Van Der Velden, M.G., Hendriks, M., Klomp, L.W., Berger, R., De Koning, T.J. Ann. Neurol. (2006) [Pubmed]
  26. Antisense repression of the chloroplast triose phosphate translocator affects carbon partitioning in transgenic potato plants. Riesmeier, J.W., Flügge, U.I., Schulz, B., Heineke, D., Heldt, H.W., Willmitzer, L., Frommer, W.B. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  27. NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase from Thermoproteus tenax. The first identified archaeal member of the aldehyde dehydrogenase superfamily is a glycolytic enzyme with unusual regulatory properties. Brunner, N.A., Brinkmann, H., Siebers, B., Hensel, R. J. Biol. Chem. (1998) [Pubmed]
  28. The adenine nucleotide-binding site on yeast 3-phosphoglycerate kinase. Affinity labeling of Lys-131 by pyridoxal 5'-diphospho-5'-adenosine. LaDine, J.R., Cross, R.L. J. Biol. Chem. (1991) [Pubmed]
  29. The different large subunit isoforms of Arabidopsis thaliana ADP-glucose pyrophosphorylase confer distinct kinetic and regulatory properties to the heterotetrameric enzyme. Crevillén, P., Ballicora, M.A., Mérida, A., Preiss, J., Romero, J.M. J. Biol. Chem. (2003) [Pubmed]
  30. Genetics of the synthesis of serine from glycine and the utilization of glycine as sole nitrogen source by Saccharomyces cerevisiae. Sinclair, D.A., Dawes, I.W. Genetics (1995) [Pubmed]
  31. Identification, sequence analysis, and expression of a Corynebacterium glutamicum gene cluster encoding the three glycolytic enzymes glyceraldehyde-3-phosphate dehydrogenase, 3-phosphoglycerate kinase, and triosephosphate isomerase. Eikmanns, B.J. J. Bacteriol. (1992) [Pubmed]
  32. The glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase works as an arsenate reductase in human red blood cells and rat liver cytosol. Gregus, Z., Németi, B. Toxicol. Sci. (2005) [Pubmed]
  33. Analysis of allosteric effector binding sites of potato ADP-glucose pyrophosphorylase through reverse genetics. Kavakli, I.H., Park, J.S., Slattery, C.J., Salamone, P.R., Frohlick, J., Okita, T.W. J. Biol. Chem. (2001) [Pubmed]
  34. Immunological and structural relatedness of isozymes and genetic variants of 3-phosphoglycerate kinase from the mouse. Lee, C.Y., Niesel, D., Pegoraro, B., Erickson, R.P. J. Biol. Chem. (1980) [Pubmed]
  35. Chromatin structure of active and inactive human X chromosomes. Riley, D.E., Canfield, T.K., Gartler, S.M. Nucleic Acids Res. (1984) [Pubmed]
  36. Purification, crystallization and preliminary X-ray analysis of the 3-phosphoglycerate kinase from Bacillus stearothermophilus. Davies, G.J., Gamblin, S.J., Littlechild, J.A., Watson, H.C. J. Mol. Biol. (1992) [Pubmed]
  37. Hepatic nucleotide triphosphate regeneration after hypothermic reperfusion in the pig model: an in vitro P-NMR study. Changani, K.K., Fuller, B.J., Bell, J.D., Bryant, D.J., Moore, D.P., Taylor-Robinson, S.D., Davidson, B.R. Transplantation (1996) [Pubmed]
WikiGenes - Universities