Gene Review:
Gip - gastric inhibitory polypeptide
Rattus norvegicus
Synonyms:
GIP, Gastric inhibitory polypeptide, Glucose-dependent insulinotropic polypeptide, Gludins, RATGLUDINS
- Postprandial stimulation of insulin release by glucose-dependent insulinotropic polypeptide (GIP). Effect of a specific glucose-dependent insulinotropic polypeptide receptor antagonist in the rat. Tseng, C.C., Kieffer, T.J., Jarboe, L.A., Usdin, T.B., Wolfe, M.M. J. Clin. Invest. (1996)
- Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: ligand binding and intracellular signaling properties. Wheeler, M.B., Gelling, R.W., McIntosh, C.H., Georgiou, J., Brown, J.C., Pederson, R.A. Endocrinology (1995)
- Identification of a bioactive domain in the amino-terminus of glucose-dependent insulinotropic polypeptide (GIP). Hinke, S.A., Manhart, S., Pamir, N., Demuth, H., W Gelling, R., Pederson, R.A., McIntosh, C.H. Biochim. Biophys. Acta (2001)
- Effects of cholecystokinin, gastric inhibitory polypeptide, and secretin on insulin and glucagon secretion in rats. Szecówka, J., Lins, P.E., Efendić, S. Endocrinology (1982)
- Binding specificity and signal transduction of receptors for glucagon-like peptide-1(7-36)amide and gastric inhibitory polypeptide on RINm5F insulinoma cells. Gallwitz, B., Witt, M., Fölsch, U.R., Creutzfeldt, W., Schmidt, W.E. J. Mol. Endocrinol. (1993)
- Dietary regulation of glucose-dependent insulinotropic peptide (GIP) gene expression in rat small intestine. Higashimoto, Y., Opara, E.C., Liddle, R.A. Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. (1995)
- Release of gastric inhibitory polypeptide (GIP) by intraduodenal acidification in rats and humans and abolishment of the incretin effect of acid by GIP-antiserum in rats. Ebert, R., Illmer, K., Creutzfeldt, W. Gastroenterology (1979)
- Structure-activity relationships of gastrointestinal hormones: motilin, GIP, and [27-TYR]CCK-PZ. Yajima, H., Kai, Y., Ogawa, H., Kubota, M., Mori, Y. Gastroenterology (1977)
- Glucose-dependent insulinotropic peptide: structure of the precursor and tissue-specific expression in rat. Tseng, C.C., Jarboe, L.A., Landau, S.B., Williams, E.K., Wolfe, M.M. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Amylin (islet amyloid polypeptide) inhibition of insulin release in the perfused rat pancreas: implication of the adenylate cyclase/cAMP system. Silvestre, R.A., Salas, M., García-Hermida, O., Fontela, T., Dégano, P., Marco, J. Regul. Pept. (1994)
- Galanin inhibits glucagon-like peptide-1 secretion through pertussis toxin-sensitive G protein and ATP-dependent potassium channels in rat ileal L-cells. Saïfia, S., Chevrier, A.M., Bosshard, A., Cuber, J.C., Chayvialle, J.A., Abello, J. J. Endocrinol. (1998)
- Defective glucose-dependent insulinotropic polypeptide receptor expression in diabetic fatty Zucker rats. Lynn, F.C., Pamir, N., Ng, E.H., McIntosh, C.H., Kieffer, T.J., Pederson, R.A. Diabetes (2001)
- Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism. Ding, W.G., Renström, E., Rorsman, P., Buschard, K., Gromada, J. Diabetes (1997)
- Functional GIP receptors are present on adipocytes. Yip, R.G., Boylan, M.O., Kieffer, T.J., Wolfe, M.M. Endocrinology (1998)
- Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells. Nakagawa, A., Satake, H., Nakabayashi, H., Nishizawa, M., Furuya, K., Nakano, S., Kigoshi, T., Nakayama, K., Uchida, K. Autonomic neuroscience : basic & clinical. (2004)
- Gastric inhibitory polypeptide receptor, a member of the secretin-vasoactive intestinal peptide receptor family, is widely distributed in peripheral organs and the brain. Usdin, T.B., Mezey, E., Button, D.C., Brownstein, M.J., Bonner, T.I. Endocrinology (1993)
- Expression and functional activity of glucagon, glucagon-like peptide I, and glucose-dependent insulinotropic peptide receptors in rat pancreatic islet cells. Moens, K., Heimberg, H., Flamez, D., Huypens, P., Quartier, E., Ling, Z., Pipeleers, D., Gremlich, S., Thorens, B., Schuit, F. Diabetes (1996)
- Chronic desensitization of the glucose-dependent insulinotropic polypeptide receptor in diabetic rats. Tseng, C.C., Boylan, M.O., Jarboe, L.A., Usdin, T.B., Wolfe, M.M. Am. J. Physiol. (1996)
- Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway. Ehses, J.A., Pelech, S.L., Pederson, R.A., McIntosh, C.H. J. Biol. Chem. (2002)
- Effects of various gastrointestinal peptides on parietal cells and endocrine cells in the oxyntic mucosa of rat stomach. El Munshid, H.A., Håkanson, R., Liedberg, G., Sundler, F. J. Physiol. (Lond.) (1980)
- Molecular cloning of rat glucose-dependent insulinotropic peptide (GIP). Higashimoto, Y., Simchock, J., Liddle, R.A. Biochim. Biophys. Acta (1992)
- Glucose-dependent insulinotropic polypeptide confers early phase insulin release to oral glucose in rats: demonstration by a receptor antagonist. Lewis, J.T., Dayanandan, B., Habener, J.F., Kieffer, T.J. Endocrinology (2000)
- Inhibition of gastrin release by gastric inhibitory peptide mediated by somatostatin. Wolfe, M.M., Reel, G.M. Am. J. Physiol. (1986)
- Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV. Kieffer, T.J., McIntosh, C.H., Pederson, R.A. Endocrinology (1995)
- Investigations into the actions of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1(7-36)amide on lipoprotein lipase activity in explants of rat adipose tissue. Knapper, J.M., Puddicombe, S.M., Morgan, L.M., Fletcher, J.M. J. Nutr. (1995)
- Heterologous desensitization of insulin secretion by GIP (glucose-dependent insulinotropic peptide) in INS-1 cells: the significance of Galphai2 and investigations on the mechanism involved. Rucha, A., Verspohl, E.J. Cell Biochem. Funct. (2005)
- Release of bombesin-like immunoreactivity from the isolated perfused rat stomach. Schusdziarra, V., Bender, H., Pfeiffer, E.F. Regul. Pept. (1983)
- Inhibitory effect of nociceptin on somatostatin secretion of the isolated perfused rat stomach. Lippl, F., Schusdziarra, V., Huepgens, K., Allescher, H.D. Regul. Pept. (2002)
- Gastric inhibitory polypeptide (GIP) binding sites in rat brain. Kaplan, A.M., Vigna, S.R. Peptides (1994)
- Gastric inhibitory polypeptide and glucagon-like peptide-1(7-36) amide exert similar effects on somatostatin secretion but opposite effects on gastrin secretion from the rat stomach. Jia, X., Brown, J.C., Kwok, Y.N., Pederson, R.A., McIntosh, C.H. Can. J. Physiol. Pharmacol. (1994)
- Characterization of the carboxyl-terminal domain of the rat glucose-dependent insulinotropic polypeptide (GIP) receptor. A role for serines 426 and 427 in regulating the rate of internalization. Wheeler, M.B., Gelling, R.W., Hinke, S.A., Tu, B., Pederson, R.A., Lynn, F., Ehses, J., McIntosh, C.H. J. Biol. Chem. (1999)